Survival Analysis
Colorectal Cancer | Ferroptosis | Unique Genes per RCD Type | Log Fold Change
Mark Edward M. Gonzales1
Dr. Anish M.S. Shrestha2
I. Preliminaries
Loading libraries
library("tidyverse")
library("tibble")
library("msigdbr")
library("ggplot2")
library("TCGAbiolinks")
library("RNAseqQC")
library("DESeq2")
library("ensembldb")
library("purrr")
library("magrittr")
library("vsn")
library("matrixStats")
library("dplyr")
library("grex")
library("survminer")
library("survival")II. Downloading the TCGA gene expression data
Create a function for downloading TCGA gene expression data.
For more detailed documentation, refer to
2. Differential Gene Expression Analysis - TCGA.Rmd.
query_and_filter_samples <- function(project) {
query_tumor <- GDCquery(
project = project,
data.category = "Transcriptome Profiling",
data.type = "Gene Expression Quantification",
experimental.strategy = "RNA-Seq",
workflow.type = "STAR - Counts",
access = "open",
sample.type = "Primary Tumor"
)
tumor <- getResults(query_tumor)
query_normal <- GDCquery(
project = project,
data.category = "Transcriptome Profiling",
data.type = "Gene Expression Quantification",
experimental.strategy = "RNA-Seq",
workflow.type = "STAR - Counts",
access = "open",
sample.type = "Solid Tissue Normal"
)
normal <- getResults(query_normal)
submitter_ids <- inner_join(tumor, normal, by = "cases.submitter_id") %>%
dplyr::select(cases.submitter_id)
tumor <- tumor %>%
dplyr::filter(cases.submitter_id %in% submitter_ids$cases.submitter_id)
normal <- normal %>%
dplyr::filter(cases.submitter_id %in% submitter_ids$cases.submitter_id)
samples <- rbind(tumor, normal)
unique(samples$sample_type)
query_project <- GDCquery(
project = project,
data.category = "Transcriptome Profiling",
data.type = "Gene Expression Quantification",
experimental.strategy = "RNA-Seq",
workflow.type = "STAR - Counts",
access = "open",
sample.type = c("Solid Tissue Normal", "Primary Tumor"),
barcode = as.list(samples$sample.submitter_id)
)
# If this is your first time running this notebook (i.e., you have not yet downloaded the results of the query in the previous block),
# uncomment the line below
# GDCdownload(query_project)
return(list(samples = samples, query_project = query_project))
}Download the TCGA gene expression data for colorectal cancer (TCGA-COAD).
projects <- c("TCGA-COAD")
with_results_projects <- c()
samples <- list()
project_data <- list()
for (project in projects) {
result <- tryCatch(
{
result <- query_and_filter_samples(project)
samples[[project]] <- result$samples
project_data[[project]] <- result$query_project
with_results_projects <- c(with_results_projects, project)
},
error = function(e) {
}
)
}Running the code block above should generate and populate a directory
named GDCdata.
III. Data preprocessing
Construct the RNA-seq count matrix for each cancer type.
tcga_data <- list()
tcga_matrix <- list()
projects <- with_results_projects
for (project in projects) {
tcga_data[[project]] <- GDCprepare(project_data[[project]], summarizedExperiment = TRUE)
}for (project in projects) {
count_matrix <- assay(tcga_data[[project]], "unstranded")
# Remove duplicate entries
count_matrix_df <- data.frame(count_matrix)
count_matrix_df <- count_matrix_df[!duplicated(count_matrix_df), ]
count_matrix <- data.matrix(count_matrix_df)
rownames(count_matrix) <- cleanid(rownames(count_matrix))
count_matrix <- count_matrix[!(duplicated(rownames(count_matrix)) | duplicated(rownames(count_matrix), fromLast = TRUE)), ]
tcga_matrix[[project]] <- count_matrix
}Format the samples table so that it can be fed as input
to DESeq2.
for (project in projects) {
rownames(samples[[project]]) <- samples[[project]]$cases
samples[[project]] <- samples[[project]] %>%
dplyr::select(case = "cases.submitter_id", type = "sample_type")
samples[[project]]$type <- str_replace(samples[[project]]$type, "Solid Tissue Normal", "normal")
samples[[project]]$type <- str_replace(samples[[project]]$type, "Primary Tumor", "tumor")
}DESeq2 requires the row names of samples should be
identical to the column names of count_matrix.
for (project in projects) {
colnames(tcga_matrix[[project]]) <- gsub(x = colnames(tcga_matrix[[project]]), pattern = "\\.", replacement = "-")
tcga_matrix[[project]] <- tcga_matrix[[project]][, rownames(samples[[project]])]
# Sanity check
print(all(colnames(tcga_matrix[[project]]) == rownames(samples[[project]])))
}IV. Differential gene expression analysis
For more detailed documentation on obtaining the gene set, refer to
7. Differential Gene Expression Analysis - TCGA - Pan-cancer - Unique Genes.Rmd.
RCDdb <- "temp/unique_genes/necroptosis_ferroptosis_pyroptosis/"Write utility functions for filtering the gene sets, performing differential gene expression analysis, plotting the results, and performing variance-stabilizing transformation.
filter_gene_set_and_perform_dgea <- function(genes) {
tcga_rcd <- list()
for (project in projects) {
rownames(genes) <- genes$gene_id
tcga_rcd[[project]] <- tcga_matrix[[project]][rownames(tcga_matrix[[project]]) %in% genes$gene_id, ]
tcga_rcd[[project]] <- tcga_rcd[[project]][, rownames(samples[[project]])]
}
dds_rcd <- list()
res_rcd <- list()
for (project in projects) {
print(project)
print("=============")
dds <- DESeqDataSetFromMatrix(
countData = tcga_rcd[[project]],
colData = samples[[project]],
design = ~type
)
dds <- filter_genes(dds, min_count = 10)
dds$type <- relevel(dds$type, ref = "normal")
dds_rcd[[project]] <- DESeq(dds)
res_rcd[[project]] <- results(dds_rcd[[project]])
}
deseq.bbl.data <- list()
for (project in projects) {
deseq.results <- res_rcd[[project]]
deseq.bbl.data[[project]] <- data.frame(
row.names = rownames(deseq.results),
baseMean = deseq.results$baseMean,
log2FoldChange = deseq.results$log2FoldChange,
lfcSE = deseq.results$lfcSE,
stat = deseq.results$stat,
pvalue = deseq.results$pvalue,
padj = deseq.results$padj,
cancer_type = project,
gene_symbol = genes[rownames(deseq.results), "gene"]
)
}
deseq.bbl.data.combined <- bind_rows(deseq.bbl.data)
deseq.bbl.data.combined <- dplyr::filter(deseq.bbl.data.combined, abs(log2FoldChange) >= 1.5 & padj < 0.05)
return(deseq.bbl.data.combined)
}plot_dgea <- function(deseq.bbl.data.combined) {
sizes <- c("<10^-15" = 4, "10^-10" = 3, "10^-5" = 2, "0.05" = 1)
deseq.bbl.data.combined <- deseq.bbl.data.combined %>%
mutate(fdr_category = cut(padj,
breaks = c(-Inf, 1e-15, 1e-10, 1e-5, 0.05),
labels = c("<10^-15", "10^-10", "10^-5", "0.05"),
right = FALSE
))
top_genes <- deseq.bbl.data.combined %>%
group_by(cancer_type) %>%
mutate(rank = rank(-abs(log2FoldChange))) %>%
dplyr::filter(rank <= 10) %>%
ungroup()
ggplot(top_genes, aes(y = cancer_type, x = gene_symbol, size = fdr_category, fill = log2FoldChange)) +
geom_point(alpha = 0.5, shape = 21, color = "black") +
scale_size_manual(values = sizes) +
scale_fill_gradient2(low = "blue", mid = "white", high = "red", limits = c(min(deseq.bbl.data.combined$log2FoldChange), max(deseq.bbl.data.combined$log2FoldChange))) +
theme_minimal() +
theme(
axis.text.x = element_text(size = 9, angle = 90, hjust = 1)
) +
theme(legend.position = "bottom") +
theme(legend.position = "bottom") +
labs(size = "Adjusted p-value", fill = "log2 FC", y = "Cancer type", x = "Gene")
}perform_vsd <- function(genes) {
tcga_rcd <- list()
for (project in projects) {
rownames(genes) <- genes$gene_id
tcga_rcd[[project]] <- tcga_matrix[[project]][rownames(tcga_matrix[[project]]) %in% genes$gene_id, ]
tcga_rcd[[project]] <- tcga_rcd[[project]][, rownames(samples[[project]])]
}
vsd_rcd <- list()
for (project in projects) {
print(project)
print("=============")
dds <- DESeqDataSetFromMatrix(
countData = tcga_rcd[[project]],
colData = samples[[project]],
design = ~type
)
dds <- filter_genes(dds, min_count = 10)
# Perform variance stabilization
dds <- estimateSizeFactors(dds)
nsub <- sum(rowMeans(counts(dds, normalized = TRUE)) > 10)
vsd <- vst(dds, nsub = nsub)
vsd_rcd[[project]] <- assay(vsd)
}
return(vsd_rcd)
}Ferroptosis
Fetch the gene set of interest.
genes <- read.csv(paste0(RCDdb, "Ferroptosis.csv"))
print(genes)genes$gene_id <- cleanid(genes$gene_id)
genes <- distinct(genes, gene_id, .keep_all = TRUE)
genes <- subset(genes, gene_id != "")
genesFilter the genes to include only those in the gene set of interest, and then perform differential gene expression analysis.
deseq.bbl.data.combined <- filter_gene_set_and_perform_dgea(genes)[1] "TCGA-COAD"
[1] "============="Warning: some variables in design formula are characters, converting to factorsestimating size factors
estimating dispersions
gene-wise dispersion estimates
mean-dispersion relationship
final dispersion estimates
fitting model and testing
-- replacing outliers and refitting for 21 genes
-- DESeq argument 'minReplicatesForReplace' = 7
-- original counts are preserved in counts(dds)
estimating dispersions
fitting model and testingdeseq.bbl.data.combinedPlot the results.
plot_dgea(deseq.bbl.data.combined)
Perform variance-stabilizing transformation for further downstream analysis (i.e., for survival analysis).
vsd <- perform_vsd(genes)[1] "TCGA-COAD"
[1] "============="V. Downloading the clinical data
Download clinical data from TCGA, and perform some preprocessing: -
The deceased column should be FALSE if the
patient is alive and TRUE otherwise - The
overall_survival column should reflect the follow-up time
if the patient is alive and the days to death otherwise
download_clinical_data <- function(project) {
clinical_data <- GDCquery_clinic(project)
clinical_data$deceased <- ifelse(clinical_data$vital_status == "Alive", FALSE, TRUE)
clinical_data$overall_survival <- ifelse(clinical_data$vital_status == "Alive",
clinical_data$days_to_last_follow_up,
clinical_data$days_to_death
)
return(clinical_data)
}tcga_clinical <- list()
for (project in projects) {
tcga_clinical[[project]] <- download_clinical_data(project)
}VI. Performing survival analysis
Write utility functions for performing survival analysis.
construct_gene_df <- function(gene_of_interest, project) {
normal_df <- tcga_matrix[[project]] %>%
as.data.frame() %>%
rownames_to_column(var = "gene_id") %>%
gather(key = "case_id", value = "counts", -gene_id) %>%
left_join(., genes, by = "gene_id") %>%
dplyr::filter(gene == gene_of_interest) %>%
dplyr::filter(case_id %in% rownames(samples[[project]] %>% dplyr::filter(type == "normal")))
normal_df$case_id <- paste0(sapply(strsplit(as.character(normal_df$case_id), "-"), `[`, 1), '-',
sapply(strsplit(as.character(normal_df$case_id), "-"), `[`, 2), '-',
sapply(strsplit(as.character(normal_df$case_id), "-"), `[`, 3))
tumor_df <- tcga_matrix[[project]] %>%
as.data.frame() %>%
rownames_to_column(var = "gene_id") %>%
gather(key = "case_id", value = "counts", -gene_id) %>%
left_join(., genes, by = "gene_id") %>%
dplyr::filter(gene == gene_of_interest) %>%
dplyr::filter(case_id %in% rownames(samples[[project]] %>% dplyr::filter(type == "tumor")))
tumor_df$case_id <- paste0(sapply(strsplit(as.character(tumor_df$case_id), "-"), `[`, 1), '-',
sapply(strsplit(as.character(tumor_df$case_id), "-"), `[`, 2), '-',
sapply(strsplit(as.character(tumor_df$case_id), "-"), `[`, 3))
gene_df <- inner_join(normal_df, tumor_df, by = c("gene_id", "case_id", "deathtype", "gene", "description", "gene_biotype", "pmid", "comment"))
gene_df$log_fold = log2(gene_df$counts.y / gene_df$counts.x)
gene_df$strata <- ifelse(abs(gene_df$log_fold) >= 1.5, "HIGH", "LOW")
gene_df <- merge(gene_df, tcga_clinical[[project]], by.x = "case_id", by.y = "submitter_id")
return(gene_df)
}compute_surival_fit <- function(gene_df) {
return (survfit(Surv(overall_survival, deceased) ~ strata, data = gene_df))
}compute_cox <- function(gene_df) {
return (coxph(Surv(overall_survival, deceased) ~ strata, data=gene_df))
}plot_survival <- function(fit) {
return(ggsurvplot(fit,
data = gene_df,
pval = T,
risk.table = T,
risk.table.height = 0.3
))
}compute_survival_diff <- function(gene_df) {
return(survdiff(Surv(overall_survival, deceased) ~ strata, data = gene_df))
}Perform survival analysis by testing for the difference in the Kaplan-Meier curves using the G-rho family of Harrington and Fleming tests: https://rdrr.io/cran/survival/man/survdiff.html
Our genes of interest are the differentially expressed genes.
significant_projects <- c()
significant_genes <- c()
ctr <- 1
for (project in projects) {
for (gene in c(genes$gene)) {
cat(project, gene, "\n\n")
error <- tryCatch (
{
gene_df <- construct_gene_df(gene, project)
},
error = function(e) {
cat("\n\n============================\n\n")
e
}
)
if(inherits(error, "error")) next
if (nrow(gene_df) > 0) {
fit <- compute_surival_fit(gene_df)
tryCatch (
{
survival <- compute_survival_diff(gene_df)
cox <- compute_cox(gene_df)
print(ctr)
ctr <- ctr + 1
print(survival)
cat("\n")
print(cox)
print(plot_survival(fit))
if (pchisq(survival$chisq, length(survival$n)-1, lower.tail = FALSE) < 0.05) {
significant_projects <- c(significant_projects, project)
significant_genes <- c(significant_genes, gene)
}
},
error = function(e) {
}
)
}
cat("\n\n============================\n\n")
}
}TCGA-COAD MIR212
============================
TCGA-COAD NR5A2
[1] 1
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 38 9 10.62 0.246 2.25
strata=LOW 8 3 1.38 1.891 2.25
Chisq= 2.3 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.0275 2.7940 0.7142 1.439 0.15
Likelihood ratio test=1.81 on 1 df, p=0.1791
n= 46, number of events= 12
============================
TCGA-COAD TFAM
[1] 2
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.82 0.2362 0.334
strata=LOW 34 10 9.18 0.0724 0.334
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4556 1.5771 0.7952 0.573 0.567
Likelihood ratio test=0.36 on 1 df, p=0.55
n= 46, number of events= 12
============================
TCGA-COAD CREB5
[1] 3
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 20 3 4.95 0.766 1.52
strata=LOW 26 9 7.05 0.538 1.52
Chisq= 1.5 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.9363 2.5505 0.7856 1.192 0.233
Likelihood ratio test=1.69 on 1 df, p=0.1931
n= 46, number of events= 12
============================
TCGA-COAD NOS2
[1] 4
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 26 7 6.93 0.000614 0.00158
strata=LOW 20 5 5.07 0.000840 0.00158
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.02426 0.97604 0.61006 -0.04 0.968
Likelihood ratio test=0 on 1 df, p=0.9683
n= 46, number of events= 12
============================
TCGA-COAD HULC
[1] 5
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 18 3 3.95 0.229 0.365
strata=LOW 28 9 8.05 0.112 0.365
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4104 1.5075 0.6837 0.6 0.548
Likelihood ratio test=0.38 on 1 df, p=0.5373
n= 46, number of events= 12
============================
TCGA-COAD PLXNB2
[1] 6
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 14 3 3.52 0.0774 0.122
strata=LOW 32 9 8.48 0.0321 0.122
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2435 1.2757 0.6974 0.349 0.727
Likelihood ratio test=0.13 on 1 df, p=0.7232
n= 46, number of events= 12
============================
TCGA-COAD KIF20A
[1] 7
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 23 7 6.89 0.00167 0.00442
strata=LOW 23 5 5.11 0.00225 0.00442
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.04123 0.95961 0.62022 -0.066 0.947
Likelihood ratio test=0 on 1 df, p=0.947
n= 46, number of events= 12
============================
TCGA-COAD TIMP1
[1] 8
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 26 8 7.08 0.119 0.319
strata=LOW 20 4 4.92 0.171 0.319
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3566 0.7001 0.6345 -0.562 0.574
Likelihood ratio test=0.32 on 1 df, p=0.5693
n= 46, number of events= 12
============================
TCGA-COAD MIR615
============================
TCGA-COAD MIR93
[1] 9
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
n=43, 3 observations deleted due to missingness.
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 26 5 6.5 0.347 0.9
strata=LOW 17 7 5.5 0.411 0.9
Chisq= 0.9 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5806 1.7871 0.6195 0.937 0.349
Likelihood ratio test=0.88 on 1 df, p=0.3488
n= 43, number of events= 12
(3 observations deleted due to missingness)
============================
TCGA-COAD ENO3
[1] 10
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 7 2 1.28 0.4003 0.461
strata=LOW 39 10 10.72 0.0479 0.461
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5314 0.5878 0.7922 -0.671 0.502
Likelihood ratio test=0.4 on 1 df, p=0.5253
n= 46, number of events= 12
============================
TCGA-COAD MMD
[1] 11
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.39 0.1573 0.209
strata=LOW 34 9 9.61 0.0391 0.209
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3157 0.7293 0.6940 -0.455 0.649
Likelihood ratio test=0.2 on 1 df, p=0.6563
n= 46, number of events= 12
============================
TCGA-COAD NQO1
[1] 12
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 21 6 4.49 0.510 0.872
strata=LOW 25 6 7.51 0.304 0.872
Chisq= 0.9 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5629 0.5696 0.6103 -0.922 0.356
Likelihood ratio test=0.85 on 1 df, p=0.3552
n= 46, number of events= 12
============================
TCGA-COAD MARCHF5
[1] 13
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 10 3 2.45 0.1240 0.165
strata=LOW 36 9 9.55 0.0318 0.165
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2796 0.7561 0.6912 -0.405 0.686
Likelihood ratio test=0.16 on 1 df, p=0.6916
n= 46, number of events= 12
============================
TCGA-COAD JUN
[1] 14
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 17 4 2.99 0.344 0.503
strata=LOW 29 8 9.01 0.114 0.503
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4606 0.6309 0.6551 -0.703 0.482
Likelihood ratio test=0.48 on 1 df, p=0.4897
n= 46, number of events= 12
============================
TCGA-COAD ALDH3A2
[1] 15
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 16 3 4.34 0.412 0.699
strata=LOW 30 9 7.66 0.233 0.699
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5650 1.7595 0.6843 0.826 0.409
Likelihood ratio test=0.73 on 1 df, p=0.3921
n= 46, number of events= 12
============================
TCGA-COAD ALOX5
[1] 16
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 21 6 6.86 0.107 0.268
strata=LOW 25 6 5.14 0.142 0.268
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3128 1.3672 0.6066 0.516 0.606
Likelihood ratio test=0.27 on 1 df, p=0.6051
n= 46, number of events= 12
============================
TCGA-COAD PARP9
[1] 17
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 13 3 4.92 0.751 1.55
strata=LOW 33 9 7.08 0.523 1.55
Chisq= 1.6 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.9637 2.6213 0.7998 1.205 0.228
Likelihood ratio test=1.72 on 1 df, p=0.1892
n= 46, number of events= 12
============================
TCGA-COAD GLRX5
[1] 18
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 14 3 3.39 0.0457 0.0695
strata=LOW 32 9 8.61 0.0180 0.0695
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1820 1.1997 0.6916 0.263 0.792
Likelihood ratio test=0.07 on 1 df, p=0.79
n= 46, number of events= 12
============================
TCGA-COAD METTL14
[1] 19
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 16 3 3.8 0.1691 0.275
strata=LOW 30 9 8.2 0.0784 0.275
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3615 1.4354 0.6927 0.522 0.602
Likelihood ratio test=0.28 on 1 df, p=0.5939
n= 46, number of events= 12
============================
TCGA-COAD TOR2A
[1] 20
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.98 0.320 0.462
strata=LOW 35 10 9.02 0.106 0.462
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5339 1.7056 0.7944 0.672 0.502
Likelihood ratio test=0.5 on 1 df, p=0.4802
n= 46, number of events= 12
============================
TCGA-COAD PARP14
[1] 21
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 19 3 4.83 0.691 1.23
strata=LOW 27 9 7.17 0.465 1.23
Chisq= 1.2 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7368 2.0893 0.6780 1.087 0.277
Likelihood ratio test=1.3 on 1 df, p=0.2547
n= 46, number of events= 12
============================
TCGA-COAD MIR130B
============================
TCGA-COAD CERS6-AS1
[1] 22
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 13 5 5.52 0.0481 0.134
strata=LOW 33 7 6.48 0.0410 0.134
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2735 1.3145 0.7482 0.365 0.715
Likelihood ratio test=0.14 on 1 df, p=0.7098
n= 46, number of events= 12
============================
TCGA-COAD NFS1
[1] 23
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 13 3 2.65 0.0465 0.0641
strata=LOW 33 9 9.35 0.0132 0.0641
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1759 0.8387 0.6955 -0.253 0.8
Likelihood ratio test=0.06 on 1 df, p=0.8026
n= 46, number of events= 12
============================
TCGA-COAD SLC3A2
[1] 24
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 13 3 2.5 0.0990 0.13
strata=LOW 33 9 9.5 0.0261 0.13
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2454 0.7824 0.6824 -0.36 0.719
Likelihood ratio test=0.12 on 1 df, p=0.7242
n= 46, number of events= 12
============================
TCGA-COAD ZFAS1
[1] 25
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 25 7 5.34 0.514 1.01
strata=LOW 21 5 6.66 0.412 1.01
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6252 0.5352 0.6309 -0.991 0.322
Likelihood ratio test=1.02 on 1 df, p=0.3118
n= 46, number of events= 12
============================
TCGA-COAD PANX1
[1] 26
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 8 2 1.67 0.0645 0.0777
strata=LOW 38 10 10.33 0.0104 0.0777
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2202 0.8023 0.7920 -0.278 0.781
Likelihood ratio test=0.07 on 1 df, p=0.7856
n= 46, number of events= 12
============================
TCGA-COAD HSPB1
[1] 27
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 16 4 4.87 0.155 0.312
strata=LOW 30 8 7.13 0.106 0.312
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3813 1.4642 0.6864 0.555 0.579
Likelihood ratio test=0.32 on 1 df, p=0.5691
n= 46, number of events= 12
============================
TCGA-COAD CREB1
[1] 28
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 13 2 3.02 0.347 0.507
strata=LOW 33 10 8.98 0.117 0.507
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5594 1.7497 0.7957 0.703 0.482
Likelihood ratio test=0.55 on 1 df, p=0.4594
n= 46, number of events= 12
============================
TCGA-COAD EZH2
[1] 29
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 20 6 6.03 0.000141 0.000316
strata=LOW 26 6 5.97 0.000142 0.000316
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.01085 1.01091 0.61035 0.018 0.986
Likelihood ratio test=0 on 1 df, p=0.9858
n= 46, number of events= 12
============================
TCGA-COAD SLC40A1
[1] 30
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 19 4 4.11 0.00290 0.00498
strata=LOW 27 8 7.89 0.00151 0.00498
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.04581 1.04687 0.64894 0.071 0.944
Likelihood ratio test=0 on 1 df, p=0.9436
n= 46, number of events= 12
============================
TCGA-COAD PAQR3
[1] 31
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.5 0.0994 0.134
strata=LOW 35 10 9.5 0.0261 0.134
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2901 1.3366 0.7948 0.365 0.715
Likelihood ratio test=0.14 on 1 df, p=0.7075
n= 46, number of events= 12
============================
TCGA-COAD MIR545
============================
TCGA-COAD MIR6077
============================
TCGA-COAD MIR424
============================
TCGA-COAD NOX5
[1] 32
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 26 3 6.23 1.67 3.94
strata=LOW 20 9 5.77 1.80 3.94
Chisq= 3.9 on 1 degrees of freedom, p= 0.05
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.2699 3.5606 0.6818 1.863 0.0625
Likelihood ratio test=3.96 on 1 df, p=0.04665
n= 46, number of events= 12
============================
TCGA-COAD DHODH
[1] 33
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 7 1 1.72 0.30 0.363
strata=LOW 39 11 10.28 0.05 0.363
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6263 1.8707 1.0558 0.593 0.553
Likelihood ratio test=0.42 on 1 df, p=0.5193
n= 46, number of events= 12
============================
TCGA-COAD PTPN18
[1] 34
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 17 3 3.77 0.1588 0.263
strata=LOW 29 9 8.23 0.0729 0.263
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3561 1.4277 0.6982 0.51 0.61
Likelihood ratio test=0.27 on 1 df, p=0.6028
n= 46, number of events= 12
============================
TCGA-COAD IARS1
[1] 35
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 13 2 2.89 0.2754 0.376
strata=LOW 33 10 9.11 0.0875 0.376
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4763 1.6101 0.7838 0.608 0.543
Likelihood ratio test=0.41 on 1 df, p=0.5237
n= 46, number of events= 12
============================
TCGA-COAD IL4R
[1] 36
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 20 4 4.49 0.0533 0.0981
strata=LOW 26 8 7.51 0.0318 0.0981
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2032 1.2254 0.6500 0.313 0.755
Likelihood ratio test=0.1 on 1 df, p=0.7532
n= 46, number of events= 12
============================
TCGA-COAD SENP1
[1] 37
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 10 2 2.18 0.01503 0.0195
strata=LOW 36 10 9.82 0.00334 0.0195
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1109 1.1173 0.7952 0.139 0.889
Likelihood ratio test=0.02 on 1 df, p=0.8879
n= 46, number of events= 12
============================
TCGA-COAD IFNA16
============================
TCGA-COAD SOX2
[1] 38
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 33 10 8.77 0.173 0.675
strata=LOW 13 2 3.23 0.469 0.675
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6354 0.5297 0.7860 -0.808 0.419
Likelihood ratio test=0.74 on 1 df, p=0.3897
n= 46, number of events= 12
============================
TCGA-COAD LIFR
[1] 39
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 39 11 10.56 0.0179 0.157
strata=LOW 7 1 1.44 0.1319 0.157
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4177 0.6585 1.0613 -0.394 0.694
Likelihood ratio test=0.17 on 1 df, p=0.6779
n= 46, number of events= 12
============================
TCGA-COAD MIR199A2
============================
TCGA-COAD COX4I2
[1] 40
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 14 3 3.45 0.0597 0.0895
strata=LOW 32 9 8.55 0.0241 0.0895
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2046 1.2270 0.6851 0.299 0.765
Likelihood ratio test=0.09 on 1 df, p=0.762
n= 46, number of events= 12
============================
TCGA-COAD ATF2
[1] 41
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 3 3.61 0.1030 0.162
strata=LOW 31 9 8.39 0.0443 0.162
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2783 1.3209 0.6927 0.402 0.688
Likelihood ratio test=0.17 on 1 df, p=0.6827
n= 46, number of events= 12
============================
TCGA-COAD ABCC5
[1] 42
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 17 5 3.8 0.381 0.586
strata=LOW 29 7 8.2 0.177 0.586
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4610 0.6307 0.6074 -0.759 0.448
Likelihood ratio test=0.56 on 1 df, p=0.4529
n= 46, number of events= 12
============================
TCGA-COAD CCDC6
[1] 43
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.98 0.353 0.503
strata=LOW 34 8 9.02 0.116 0.503
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4546 0.6347 0.6462 -0.703 0.482
Likelihood ratio test=0.48 on 1 df, p=0.49
n= 46, number of events= 12
============================
TCGA-COAD OTUB1
[1] 44
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 3 0 0.781 0.7811 0.857
strata=LOW 43 12 11.219 0.0544 0.857
Chisq= 0.9 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.815e+01 7.607e+07 9.423e+03 0.002 0.998
Likelihood ratio test=1.64 on 1 df, p=0.201
n= 46, number of events= 12
============================
TCGA-COAD ALOXE3
[1] 45
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
n=41, 5 observations deleted due to missingness.
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 29 9 9.23 0.00597 0.0268
strata=LOW 12 3 2.77 0.01993 0.0268
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1113 1.1178 0.6800 0.164 0.87
Likelihood ratio test=0.03 on 1 df, p=0.871
n= 41, number of events= 12
(5 observations deleted due to missingness)
============================
TCGA-COAD SCP2
[1] 46
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 21 5 5.15 0.00431 0.00839
strata=LOW 25 7 6.85 0.00324 0.00839
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.05643 1.05805 0.61604 0.092 0.927
Likelihood ratio test=0.01 on 1 df, p=0.927
n= 46, number of events= 12
============================
TCGA-COAD PHKG2
[1] 47
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 5 1 1.27 0.05751 0.0662
strata=LOW 41 11 10.73 0.00681 0.0662
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.271 1.311 1.056 0.257 0.798
Likelihood ratio test=0.07 on 1 df, p=0.7903
n= 46, number of events= 12
============================
TCGA-COAD MTDH
[1] 48
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.86 0.2576 0.349
strata=LOW 34 10 9.14 0.0806 0.349
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4586 1.5819 0.7828 0.586 0.558
Likelihood ratio test=0.38 on 1 df, p=0.5393
n= 46, number of events= 12
============================
TCGA-COAD ACO1
[1] 49
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.31 0.0288 0.042
strata=LOW 35 9 8.69 0.0110 0.042
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1397 1.1499 0.6825 0.205 0.838
Likelihood ratio test=0.04 on 1 df, p=0.8362
n= 46, number of events= 12
============================
TCGA-COAD MIR137
============================
TCGA-COAD OIP5-AS1
[1] 50
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 14 3 3.61 0.1030 0.162
strata=LOW 32 9 8.39 0.0443 0.162
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2783 1.3209 0.6927 0.402 0.688
Likelihood ratio test=0.17 on 1 df, p=0.6827
n= 46, number of events= 12
============================
TCGA-COAD MIR494
============================
TCGA-COAD MLLT1
[1] 51
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 9 2 1.63 0.0826 0.099
strata=LOW 37 10 10.37 0.0130 0.099
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2484 0.7801 0.7915 -0.314 0.754
Likelihood ratio test=0.09 on 1 df, p=0.7596
n= 46, number of events= 12
============================
TCGA-COAD MIR19B1
============================
TCGA-COAD RPTOR
[1] 52
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 8 1 2.2 0.653 0.842
strata=LOW 38 11 9.8 0.146 0.842
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.9346 2.5463 1.0557 0.885 0.376
Likelihood ratio test=1 on 1 df, p=0.317
n= 46, number of events= 12
============================
TCGA-COAD GCH1
[1] 53
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 4 3.42 0.0986 0.15
strata=LOW 31 8 8.58 0.0393 0.15
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2503 0.7786 0.6469 -0.387 0.699
Likelihood ratio test=0.15 on 1 df, p=0.7016
n= 46, number of events= 12
============================
TCGA-COAD PARP16
[1] 54
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.72 0.02852 0.0396
strata=LOW 35 9 9.28 0.00837 0.0396
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1381 0.8710 0.6943 -0.199 0.842
Likelihood ratio test=0.04 on 1 df, p=0.8438
n= 46, number of events= 12
============================
TCGA-COAD MIR9-3
============================
TCGA-COAD CISD3
[1] 55
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 21 4 5.79 0.552 1.23
strata=LOW 25 8 6.21 0.514 1.23
Chisq= 1.2 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6972 2.0081 0.6396 1.09 0.276
Likelihood ratio test=1.23 on 1 df, p=0.2667
n= 46, number of events= 12
============================
TCGA-COAD USP35
[1] 56
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 4 1 0.909 0.009191 0.0103
strata=LOW 42 11 11.091 0.000753 0.0103
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1076 0.8980 1.0630 -0.101 0.919
Likelihood ratio test=0.01 on 1 df, p=0.9204
n= 46, number of events= 12
============================
TCGA-COAD PRKAA1
[1] 57
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 14 4 3.37 0.1163 0.176
strata=LOW 32 8 8.63 0.0455 0.176
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2706 0.7629 0.6467 -0.418 0.676
Likelihood ratio test=0.17 on 1 df, p=0.6788
n= 46, number of events= 12
============================
TCGA-COAD MAPK14
[1] 58
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 9 3 1.56 1.328 1.58
strata=LOW 37 9 10.44 0.198 1.58
Chisq= 1.6 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8440 0.4300 0.6918 -1.22 0.222
Likelihood ratio test=1.31 on 1 df, p=0.2527
n= 46, number of events= 12
============================
TCGA-COAD GRIA3
[1] 59
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 38 9 10.38 0.184 1.45
strata=LOW 8 3 1.62 1.179 1.45
Chisq= 1.4 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8305 2.2945 0.7103 1.169 0.242
Likelihood ratio test=1.22 on 1 df, p=0.2685
n= 46, number of events= 12
============================
TCGA-COAD KDM5C
[1] 60
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 10 3 2.6 0.0624 0.0851
strata=LOW 36 9 9.4 0.0172 0.0851
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2019 0.8171 0.6935 -0.291 0.771
Likelihood ratio test=0.08 on 1 df, p=0.774
n= 46, number of events= 12
============================
TCGA-COAD DECR1
[1] 61
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 19 3 4.37 0.430 0.733
strata=LOW 27 9 7.63 0.247 0.733
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5775 1.7816 0.6834 0.845 0.398
Likelihood ratio test=0.77 on 1 df, p=0.3807
n= 46, number of events= 12
============================
TCGA-COAD VCP
[1] 62
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 10 1 2.97 1.303 1.79
strata=LOW 36 11 9.03 0.428 1.79
Chisq= 1.8 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.311 3.710 1.050 1.249 0.212
Likelihood ratio test=2.21 on 1 df, p=0.1368
n= 46, number of events= 12
============================
TCGA-COAD MIR129-1
============================
TCGA-COAD PARP10
[1] 63
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 9 2 4.08 1.060 2
strata=LOW 37 10 7.92 0.546 2
Chisq= 2 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.382 3.982 1.055 1.31 0.19
Likelihood ratio test=2.46 on 1 df, p=0.1166
n= 46, number of events= 12
============================
TCGA-COAD ULK2
[1] 64
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.23 0.01610 0.0229
strata=LOW 34 9 8.77 0.00592 0.0229
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1026 1.1081 0.6786 0.151 0.88
Likelihood ratio test=0.02 on 1 df, p=0.8789
n= 46, number of events= 12
============================
TCGA-COAD CISD1
[1] 65
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.66 0.0440 0.06
strata=LOW 35 9 9.34 0.0125 0.06
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1690 0.8445 0.6907 -0.245 0.807
Likelihood ratio test=0.06 on 1 df, p=0.8089
n= 46, number of events= 12
============================
TCGA-COAD MIR147A
============================
TCGA-COAD BBOX1-AS1
[1] 66
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 43 12 11.287 0.045 0.799
strata=LOW 3 0 0.713 0.713 0.799
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.819e+01 1.263e-08 9.926e+03 -0.002 0.999
Likelihood ratio test=1.51 on 1 df, p=0.2189
n= 46, number of events= 12
============================
TCGA-COAD RB1
[1] 67
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.5 0.0994 0.134
strata=LOW 35 10 9.5 0.0261 0.134
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2901 1.3366 0.7948 0.365 0.715
Likelihood ratio test=0.14 on 1 df, p=0.7075
n= 46, number of events= 12
============================
TCGA-COAD TTPA
[1] 68
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 27 9 7.84 0.172 0.535
strata=LOW 19 3 4.16 0.324 0.535
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4973 0.6082 0.6861 -0.725 0.469
Likelihood ratio test=0.56 on 1 df, p=0.4538
n= 46, number of events= 12
============================
TCGA-COAD CDC25A
[1] 69
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 16 4 5.45 0.387 0.822
strata=LOW 30 8 6.55 0.322 0.822
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6144 1.8485 0.6875 0.894 0.372
Likelihood ratio test=0.86 on 1 df, p=0.3528
n= 46, number of events= 12
============================
TCGA-COAD PCAT1
[1] 70
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 29 7 7.36 0.0180 0.055
strata=LOW 17 5 4.64 0.0286 0.055
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1477 1.1592 0.6305 0.234 0.815
Likelihood ratio test=0.05 on 1 df, p=0.816
n= 46, number of events= 12
============================
TCGA-COAD DAZAP1
[1] 71
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 6 1 1.52 0.1807 0.214
strata=LOW 40 11 10.48 0.0263 0.214
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4832 1.6212 1.0551 0.458 0.647
Likelihood ratio test=0.24 on 1 df, p=0.6253
n= 46, number of events= 12
============================
TCGA-COAD PEX2
[1] 72
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.5 0.0993 0.133
strata=LOW 35 9 9.5 0.0262 0.133
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2509 0.7781 0.6906 -0.363 0.716
Likelihood ratio test=0.13 on 1 df, p=0.7212
n= 46, number of events= 12
============================
TCGA-COAD MIR124-3
============================
TCGA-COAD TRIM21
[1] 73
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 9 2 2.05 0.001286 0.00163
strata=LOW 37 10 9.95 0.000265 0.00163
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.03196 1.03247 0.79247 0.04 0.968
Likelihood ratio test=0 on 1 df, p=0.9677
n= 46, number of events= 12
============================
TCGA-COAD MEG3
[1] 74
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 19 7 3.99 2.27 3.66
strata=LOW 27 5 8.01 1.13 3.66
Chisq= 3.7 on 1 degrees of freedom, p= 0.06
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.1588 0.3139 0.6371 -1.819 0.0689
Likelihood ratio test=3.48 on 1 df, p=0.06198
n= 46, number of events= 12
============================
TCGA-COAD GCLC
[1] 75
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.14 0.00861 0.0111
strata=LOW 35 10 9.86 0.00186 0.0111
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.08357 1.08716 0.79463 0.105 0.916
Likelihood ratio test=0.01 on 1 df, p=0.9156
n= 46, number of events= 12
============================
TCGA-COAD IDH2
[1] 76
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 8 1 3.73 1.996 3.65
strata=LOW 38 11 8.27 0.899 3.65
Chisq= 3.6 on 1 degrees of freedom, p= 0.06
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.947e+01 2.869e+08 8.858e+03 0.002 0.998
Likelihood ratio test=6.29 on 1 df, p=0.01213
n= 46, number of events= 12
============================
TCGA-COAD FNDC5
[1] 77
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 24 6 7.52 0.308 0.98
strata=LOW 22 6 4.48 0.518 0.98
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6492 1.9140 0.6660 0.975 0.33
Likelihood ratio test=0.98 on 1 df, p=0.3221
n= 46, number of events= 12
============================
TCGA-COAD FANCD2
[1] 78
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 20 4 4.67 0.0958 0.167
strata=LOW 26 8 7.33 0.0610 0.167
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2555 1.2911 0.6273 0.407 0.684
Likelihood ratio test=0.17 on 1 df, p=0.6807
n= 46, number of events= 12
============================
TCGA-COAD LCN2
[1] 79
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 28 7 7.33 0.0148 0.0405
strata=LOW 18 5 4.67 0.0232 0.0405
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1220 1.1297 0.6065 0.201 0.841
Likelihood ratio test=0.04 on 1 df, p=0.841
n= 46, number of events= 12
============================
TCGA-COAD TFR2
[1] 80
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 28 8 7.83 0.00377 0.0123
strata=LOW 18 4 4.17 0.00707 0.0123
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.07187 0.93065 0.64912 -0.111 0.912
Likelihood ratio test=0.01 on 1 df, p=0.9116
n= 46, number of events= 12
============================
TCGA-COAD PARP12
[1] 81
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 20 4 4.13 0.00391 0.00689
strata=LOW 26 8 7.87 0.00205 0.00689
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.05449 1.05600 0.65647 0.083 0.934
Likelihood ratio test=0.01 on 1 df, p=0.9337
n= 46, number of events= 12
============================
TCGA-COAD NR1D1
[1] 82
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 14 2 2.86 0.2597 0.383
strata=LOW 32 10 9.14 0.0813 0.383
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4920 1.6356 0.8033 0.612 0.54
Likelihood ratio test=0.41 on 1 df, p=0.5229
n= 46, number of events= 12
============================
TCGA-COAD ATG13
[1] 83
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 2 3.47 0.621 0.975
strata=LOW 31 10 8.53 0.252 0.975
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7685 2.1564 0.7968 0.964 0.335
Likelihood ratio test=1.06 on 1 df, p=0.3022
n= 46, number of events= 12
============================
TCGA-COAD TMSB4X
[1] 84
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 16 2 3.16 0.424 0.632
strata=LOW 30 10 8.84 0.151 0.632
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6231 1.8648 0.7961 0.783 0.434
Likelihood ratio test=0.69 on 1 df, p=0.4077
n= 46, number of events= 12
============================
TCGA-COAD CDK14
[1] 85
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 23 4 5.35 0.340 0.688
strata=LOW 23 8 6.65 0.273 0.688
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5217 1.6849 0.6359 0.82 0.412
Likelihood ratio test=0.7 on 1 df, p=0.4043
n= 46, number of events= 12
============================
TCGA-COAD RP1-228H13.5
[1] 86
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 19 6 3.64 1.537 2.48
strata=LOW 27 6 8.36 0.668 2.48
Chisq= 2.5 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.9992 0.3682 0.6591 -1.516 0.13
Likelihood ratio test=2.37 on 1 df, p=0.1236
n= 46, number of events= 12
============================
TCGA-COAD NOX3
[1] 87
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
n=18, 28 observations deleted due to missingness.
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 17 5 4.9412 0.0007 0.0625
strata=LOW 1 0 0.0588 0.0588 0.0625
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.710e+01 3.760e-08 2.063e+04 -0.001 0.999
Likelihood ratio test=0.12 on 1 df, p=0.7277
n= 18, number of events= 5
(28 observations deleted due to missingness)
============================
TCGA-COAD IFNA17
============================
TCGA-COAD ALOX12B
[1] 88
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 33 7 6.95 0.000435 0.00124
strata=LOW 13 5 5.05 0.000598 0.00124
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.02263 0.97763 0.64250 -0.035 0.972
Likelihood ratio test=0 on 1 df, p=0.9719
n= 46, number of events= 12
============================
TCGA-COAD PGRMC1
[1] 89
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 5 3.2 1.008 1.5
strata=LOW 31 7 8.8 0.367 1.5
Chisq= 1.5 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7632 0.4662 0.6376 -1.197 0.231
Likelihood ratio test=1.4 on 1 df, p=0.2364
n= 46, number of events= 12
============================
TCGA-COAD ULK1
[1] 90
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 8 2 2.19 0.01732 0.0223
strata=LOW 38 10 9.81 0.00388 0.0223
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1183 1.1256 0.7925 0.149 0.881
Likelihood ratio test=0.02 on 1 df, p=0.8799
n= 46, number of events= 12
============================
TCGA-COAD TRIM26
[1] 91
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.26 0.03004 0.039
strata=LOW 35 10 9.74 0.00697 0.039
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1564 1.1693 0.7926 0.197 0.844
Likelihood ratio test=0.04 on 1 df, p=0.8412
n= 46, number of events= 12
============================
TCGA-COAD QSOX1
[1] 92
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 20 4 5.2 0.276 0.543
strata=LOW 26 8 6.8 0.211 0.543
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4646 1.5913 0.6359 0.731 0.465
Likelihood ratio test=0.55 on 1 df, p=0.4582
n= 46, number of events= 12
============================
TCGA-COAD ATM
[1] 93
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 20 6 5 0.198 0.374
strata=LOW 26 6 7 0.142 0.374
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3752 0.6872 0.6164 -0.609 0.543
Likelihood ratio test=0.37 on 1 df, p=0.5414
n= 46, number of events= 12
============================
TCGA-COAD MIB2
[1] 94
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.33 0.0459 0.0621
strata=LOW 35 10 9.67 0.0111 0.0621
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1997 1.2210 0.8026 0.249 0.804
Likelihood ratio test=0.06 on 1 df, p=0.8
n= 46, number of events= 12
============================
TCGA-COAD SLC1A5
[1] 95
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 14 5 2.62 2.170 3.12
strata=LOW 32 7 9.38 0.605 3.12
Chisq= 3.1 on 1 degrees of freedom, p= 0.08
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.1438 0.3186 0.6819 -1.677 0.0935
Likelihood ratio test=2.8 on 1 df, p=0.09428
n= 46, number of events= 12
============================
TCGA-COAD MIR2115
============================
TCGA-COAD LINC00336
[1] 96
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 20 5 6.18 0.225 0.515
strata=LOW 26 7 5.82 0.239 0.515
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4498 1.5681 0.6317 0.712 0.476
Likelihood ratio test=0.52 on 1 df, p=0.4692
n= 46, number of events= 12
============================
TCGA-COAD NDRG1
[1] 97
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 25 5 5.89 0.135 0.316
strata=LOW 21 7 6.11 0.130 0.316
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.351 1.421 0.627 0.56 0.576
Likelihood ratio test=0.31 on 1 df, p=0.5754
n= 46, number of events= 12
============================
TCGA-COAD TAFAZZIN
[1] 98
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 10 3 3.66 0.1196 0.221
strata=LOW 36 9 8.34 0.0525 0.221
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3685 1.4456 0.7880 0.468 0.64
Likelihood ratio test=0.24 on 1 df, p=0.6275
n= 46, number of events= 12
============================
TCGA-COAD MIR135B
============================
TCGA-COAD GLS2
[1] 99
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 29 7 6.58 0.0271 0.0685
strata=LOW 17 5 5.42 0.0329 0.0685
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1651 0.8478 0.6316 -0.261 0.794
Likelihood ratio test=0.07 on 1 df, p=0.7924
n= 46, number of events= 12
============================
TCGA-COAD HELLS
[1] 100
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 25 5 6.56 0.373 0.896
strata=LOW 21 7 5.44 0.450 0.896
Chisq= 0.9 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5874 1.7993 0.6292 0.934 0.351
Likelihood ratio test=0.91 on 1 df, p=0.341
n= 46, number of events= 12
============================
TCGA-COAD KLF2
[1] 101
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 19 4 5.2 0.278 0.53
strata=LOW 27 8 6.8 0.213 0.53
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4533 1.5735 0.6280 0.722 0.47
Likelihood ratio test=0.54 on 1 df, p=0.463
n= 46, number of events= 12
============================
TCGA-COAD TFAP2A
[1] 102
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 31 8 7.94 0.000519 0.00163
strata=LOW 15 4 4.06 0.001013 0.00163
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.02552 0.97480 0.63173 -0.04 0.968
Likelihood ratio test=0 on 1 df, p=0.9677
n= 46, number of events= 12
============================
TCGA-COAD FURIN
[1] 103
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 16 4 4.03 0.000207 0.000359
strata=LOW 30 8 7.97 0.000105 0.000359
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.01244 1.01252 0.65655 0.019 0.985
Likelihood ratio test=0 on 1 df, p=0.9849
n= 46, number of events= 12
============================
TCGA-COAD CDH1
[1] 104
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 21 8 4.32 3.12 5.56
strata=LOW 25 4 7.68 1.76 5.56
Chisq= 5.6 on 1 degrees of freedom, p= 0.02
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.6773 0.1869 0.7946 -2.111 0.0348
Likelihood ratio test=5.74 on 1 df, p=0.01663
n= 46, number of events= 12
============================
TCGA-COAD MIR6852
============================
TCGA-COAD MIR670
============================
TCGA-COAD TYRO3
[1] 105
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 20 3 4.93 0.757 1.39
strata=LOW 26 9 7.07 0.528 1.39
Chisq= 1.4 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7826 2.1872 0.6806 1.15 0.25
Likelihood ratio test=1.46 on 1 df, p=0.2274
n= 46, number of events= 12
============================
TCGA-COAD MIR4715
============================
TCGA-COAD ABHD12
[1] 106
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 18 3 3.55 0.0857 0.142
strata=LOW 28 9 8.45 0.0360 0.142
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2668 1.3057 0.7089 0.376 0.707
Likelihood ratio test=0.15 on 1 df, p=0.7029
n= 46, number of events= 12
============================
TCGA-COAD ATG7
[1] 107
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 9 2 1.88 0.00754 0.00935
strata=LOW 37 10 10.12 0.00140 0.00935
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.07666 0.92621 0.79318 -0.097 0.923
Likelihood ratio test=0.01 on 1 df, p=0.9236
n= 46, number of events= 12
============================
TCGA-COAD MT1G
[1] 108
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 44 12 11.683 0.00861 0.33
strata=LOW 2 0 0.317 0.31718 0.33
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.706e+01 3.888e-08 8.828e+03 -0.002 0.998
Likelihood ratio test=0.65 on 1 df, p=0.4212
n= 46, number of events= 12
============================
TCGA-COAD SAT1
[1] 109
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.34 0.1873 0.248
strata=LOW 34 9 9.66 0.0453 0.248
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3454 0.7079 0.6966 -0.496 0.62
Likelihood ratio test=0.23 on 1 df, p=0.6282
n= 46, number of events= 12
============================
TCGA-COAD MIR182
============================
TCGA-COAD HOTAIR
[1] 110
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
n=35, 11 observations deleted due to missingness.
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 26 8 7.52 0.0309 0.199
strata=LOW 9 1 1.48 0.1569 0.199
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4782 0.6199 1.0809 -0.442 0.658
Likelihood ratio test=0.22 on 1 df, p=0.64
n= 35, number of events= 9
(11 observations deleted due to missingness)
============================
TCGA-COAD PIR
[1] 111
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 17 3 4.5 0.499 0.849
strata=LOW 29 9 7.5 0.299 0.849
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6154 1.8505 0.6784 0.907 0.364
Likelihood ratio test=0.89 on 1 df, p=0.3449
n= 46, number of events= 12
============================
TCGA-COAD ELAVL1
[1] 112
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 3 1 0.891 0.01344 0.0148
strata=LOW 43 11 11.109 0.00108 0.0148
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1287 0.8793 1.0573 -0.122 0.903
Likelihood ratio test=0.01 on 1 df, p=0.9048
n= 46, number of events= 12
============================
TCGA-COAD ACADSB
[1] 113
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 18 5 4.31 0.1121 0.199
strata=LOW 28 7 7.69 0.0627 0.199
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2833 0.7533 0.6367 -0.445 0.656
Likelihood ratio test=0.2 on 1 df, p=0.6568
n= 46, number of events= 12
============================
TCGA-COAD NCOA4
[1] 114
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 19 4 4.51 0.0587 0.102
strata=LOW 27 8 7.49 0.0354 0.102
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2013 1.2230 0.6326 0.318 0.75
Likelihood ratio test=0.1 on 1 df, p=0.7484
n= 46, number of events= 12
============================
TCGA-COAD IFNA10
============================
TCGA-COAD IFNA13
============================
TCGA-COAD MIR9-2
============================
TCGA-COAD RRM2
[1] 115
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 22 5 6.33 0.278 0.647
strata=LOW 24 7 5.67 0.310 0.647
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5016 1.6514 0.6299 0.796 0.426
Likelihood ratio test=0.66 on 1 df, p=0.4176
n= 46, number of events= 12
============================
TCGA-COAD EPSTI1
[1] 116
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 19 5 4.83 0.00589 0.0115
strata=LOW 27 7 7.17 0.00397 0.0115
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.06725 0.93497 0.62846 -0.107 0.915
Likelihood ratio test=0.01 on 1 df, p=0.9151
n= 46, number of events= 12
============================
TCGA-COAD LINC00551
[1] 117
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 25 5 4.82 0.00649 0.0128
strata=LOW 21 7 7.18 0.00436 0.0128
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.07235 0.93020 0.63941 -0.113 0.91
Likelihood ratio test=0.01 on 1 df, p=0.9099
n= 46, number of events= 12
============================
TCGA-COAD SLC25A28
[1] 118
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 7 1 1.8 0.3533 0.433
strata=LOW 39 11 10.2 0.0622 0.433
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6815 1.9769 1.0558 0.645 0.519
Likelihood ratio test=0.5 on 1 df, p=0.48
n= 46, number of events= 12
============================
TCGA-COAD LINC00973
[1] 119
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
n=21, 25 observations deleted due to missingness.
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 19 6 5.646 0.0222 0.381
strata=LOW 2 0 0.354 0.3539 0.381
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.812e+01 1.352e-08 1.393e+04 -0.001 0.999
Likelihood ratio test=0.73 on 1 df, p=0.3914
n= 21, number of events= 6
(25 observations deleted due to missingness)
============================
TCGA-COAD MIR378A
[1] 120
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
n=41, 5 observations deleted due to missingness.
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 30 8 7.43 0.0433 0.145
strata=LOW 11 3 3.57 0.0903 0.145
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2668 0.7659 0.7016 -0.38 0.704
Likelihood ratio test=0.15 on 1 df, p=0.6993
n= 41, number of events= 11
(5 observations deleted due to missingness)
============================
TCGA-COAD MGST1
[1] 121
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 22 4 5.52 0.419 0.88
strata=LOW 24 8 6.48 0.358 0.88
Chisq= 0.9 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5897 1.8034 0.6369 0.926 0.355
Likelihood ratio test=0.89 on 1 df, p=0.3461
n= 46, number of events= 12
============================
TCGA-COAD MIB1
[1] 122
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 18 3 4.33 0.408 0.729
strata=LOW 28 9 7.67 0.230 0.729
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5844 1.7939 0.6939 0.842 0.4
Likelihood ratio test=0.76 on 1 df, p=0.3844
n= 46, number of events= 12
============================
TCGA-COAD SRC
[1] 123
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 13 3 3.17 0.00935 0.0132
strata=LOW 33 9 8.83 0.00336 0.0132
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.07822 1.08136 0.67975 0.115 0.908
Likelihood ratio test=0.01 on 1 df, p=0.9079
n= 46, number of events= 12
============================
TCGA-COAD ATG5
[1] 124
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 16 4 4.03 0.000281 0.00045
strata=LOW 30 8 7.97 0.000142 0.00045
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.01339 1.01348 0.63144 0.021 0.983
Likelihood ratio test=0 on 1 df, p=0.9831
n= 46, number of events= 12
============================
TCGA-COAD ACVR1B
[1] 125
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 20 4 4.53 0.0630 0.117
strata=LOW 26 8 7.47 0.0382 0.117
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2221 1.2487 0.6503 0.341 0.733
Likelihood ratio test=0.12 on 1 df, p=0.7312
n= 46, number of events= 12
============================
TCGA-COAD NT5DC2
[1] 126
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 17 3 4.31 0.397 0.747
strata=LOW 29 9 7.69 0.222 0.747
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6661 1.9466 0.7847 0.849 0.396
Likelihood ratio test=0.82 on 1 df, p=0.3648
n= 46, number of events= 12
============================
TCGA-COAD PIK3CA
[1] 127
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 16 2 3.34 0.539 0.828
strata=LOW 30 10 8.66 0.208 0.828
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7098 2.0336 0.7961 0.892 0.373
Likelihood ratio test=0.9 on 1 df, p=0.3423
n= 46, number of events= 12
============================
TCGA-COAD NUPR1
[1] 128
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 19 3 3.94 0.225 0.355
strata=LOW 27 9 8.06 0.110 0.355
Chisq= 0.4 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4029 1.4962 0.6808 0.592 0.554
Likelihood ratio test=0.37 on 1 df, p=0.543
n= 46, number of events= 12
============================
TCGA-COAD AKT1S1
[1] 129
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 8 1 2.37 0.791 1.05
strata=LOW 38 11 9.63 0.194 1.05
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.035 2.814 1.057 0.979 0.327
Likelihood ratio test=1.25 on 1 df, p=0.2627
n= 46, number of events= 12
============================
TCGA-COAD MIR19A
============================
TCGA-COAD USP7
[1] 130
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 14 4 2.53 0.847 1.15
strata=LOW 32 8 9.47 0.227 1.15
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6842 0.5045 0.6508 -1.051 0.293
Likelihood ratio test=1.04 on 1 df, p=0.3076
n= 46, number of events= 12
============================
TCGA-COAD TMSB4Y
[1] 131
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
n=34, 12 observations deleted due to missingness.
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 20 4 4.63 0.0859 0.258
strata=LOW 14 4 3.37 0.1181 0.258
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3893 1.4759 0.7709 0.505 0.614
Likelihood ratio test=0.25 on 1 df, p=0.6177
n= 34, number of events= 8
(12 observations deleted due to missingness)
============================
TCGA-COAD SIAH2
[1] 132
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 9 2 1.99 6.23e-05 7.81e-05
strata=LOW 37 10 10.01 1.24e-05 7.81e-05
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.006999 0.993025 0.792041 -0.009 0.993
Likelihood ratio test=0 on 1 df, p=0.993
n= 46, number of events= 12
============================
TCGA-COAD MIR29A
============================
TCGA-COAD CHAC1
[1] 133
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 19 5 5.31 0.0182 0.0379
strata=LOW 27 7 6.69 0.0144 0.0379
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1238 1.1318 0.6358 0.195 0.846
Likelihood ratio test=0.04 on 1 df, p=0.8449
n= 46, number of events= 12
============================
TCGA-COAD LINC00616
============================
TCGA-COAD PRKAA2
[1] 134
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 39 11 10.83 0.00257 0.0276
strata=LOW 7 1 1.17 0.02383 0.0276
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1766 0.8381 1.0645 -0.166 0.868
Likelihood ratio test=0.03 on 1 df, p=0.8652
n= 46, number of events= 12
============================
TCGA-COAD LONP1
[1] 135
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 1 2.02 0.514 0.668
strata=LOW 35 11 9.98 0.104 0.668
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8433 2.3241 1.0628 0.794 0.427
Likelihood ratio test=0.78 on 1 df, p=0.3774
n= 46, number of events= 12
============================
TCGA-COAD PPARG
[1] 136
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 22 7 4.51 1.368 2.53
strata=LOW 24 5 7.49 0.825 2.53
Chisq= 2.5 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.0588 0.3469 0.6956 -1.522 0.128
Likelihood ratio test=2.56 on 1 df, p=0.1097
n= 46, number of events= 12
============================
TCGA-COAD MAPK1
[1] 137
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 3 3.55 0.0844 0.132
strata=LOW 31 9 8.45 0.0354 0.132
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2503 1.2844 0.6918 0.362 0.718
Likelihood ratio test=0.13 on 1 df, p=0.7133
n= 46, number of events= 12
============================
TCGA-COAD PEX6
[1] 138
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.74 0.1476 0.228
strata=LOW 35 9 8.26 0.0669 0.228
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3247 1.3836 0.6827 0.476 0.634
Likelihood ratio test=0.24 on 1 df, p=0.6268
n= 46, number of events= 12
============================
TCGA-COAD PPARA
[1] 139
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 17 4 3.65 0.0345 0.0546
strata=LOW 29 8 8.35 0.0151 0.0546
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1510 0.8598 0.6471 -0.233 0.815
Likelihood ratio test=0.05 on 1 df, p=0.8165
n= 46, number of events= 12
============================
TCGA-COAD ACSL4
[1] 140
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 4 3.64 0.0358 0.0541
strata=LOW 31 8 8.36 0.0156 0.0541
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1466 0.8636 0.6308 -0.232 0.816
Likelihood ratio test=0.05 on 1 df, p=0.8175
n= 46, number of events= 12
============================
TCGA-COAD ANO6
[1] 141
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 16 2 3.38 0.563 0.874
strata=LOW 30 10 8.62 0.221 0.874
Chisq= 0.9 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7293 2.0737 0.7970 0.915 0.36
Likelihood ratio test=0.95 on 1 df, p=0.3292
n= 46, number of events= 12
============================
TCGA-COAD YTHDC2
[1] 142
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 16 5 3.87 0.329 0.54
strata=LOW 30 7 8.13 0.157 0.54
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4626 0.6297 0.6348 -0.729 0.466
Likelihood ratio test=0.53 on 1 df, p=0.4681
n= 46, number of events= 12
============================
TCGA-COAD MIR103A1
============================
TCGA-COAD INTS2
[1] 143
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 2 3.13 0.406 0.607
strata=LOW 31 10 8.87 0.143 0.607
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6127 1.8455 0.7982 0.768 0.443
Likelihood ratio test=0.66 on 1 df, p=0.4175
n= 46, number of events= 12
============================
TCGA-COAD PTPN6
[1] 144
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 16 3 3.21 0.01386 0.0208
strata=LOW 30 9 8.79 0.00506 0.0208
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1003 1.1055 0.6959 0.144 0.885
Likelihood ratio test=0.02 on 1 df, p=0.8847
n= 46, number of events= 12
============================
TCGA-COAD SMAD7
[1] 145
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 21 6 5.15 0.141 0.274
strata=LOW 25 6 6.85 0.106 0.274
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3221 0.7246 0.6178 -0.521 0.602
Likelihood ratio test=0.27 on 1 df, p=0.6009
n= 46, number of events= 12
============================
TCGA-COAD ATG16L1
[1] 146
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 7 1 1.72 0.30 0.363
strata=LOW 39 11 10.28 0.05 0.363
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6263 1.8707 1.0558 0.593 0.553
Likelihood ratio test=0.42 on 1 df, p=0.5193
n= 46, number of events= 12
============================
TCGA-COAD LINC00976
[1] 147
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 28 10 7.59 0.763 2.22
strata=LOW 18 2 4.41 1.315 2.22
Chisq= 2.2 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.1127 0.3287 0.7846 -1.418 0.156
Likelihood ratio test=2.47 on 1 df, p=0.116
n= 46, number of events= 12
============================
TCGA-COAD H19
[1] 148
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 28 5 5.43 0.0334 0.07
strata=LOW 18 7 6.57 0.0275 0.07
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1646 1.1790 0.6229 0.264 0.792
Likelihood ratio test=0.07 on 1 df, p=0.7913
n= 46, number of events= 12
============================
TCGA-COAD FADS1
[1] 149
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 21 5 5.25 0.01188 0.0229
strata=LOW 25 7 6.75 0.00924 0.0229
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.09183 1.09617 0.60740 0.151 0.88
Likelihood ratio test=0.02 on 1 df, p=0.8797
n= 46, number of events= 12
============================
TCGA-COAD CHP1
[1] 150
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 25 6 6.14 0.00302 0.00734
strata=LOW 21 6 5.86 0.00316 0.00734
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.05376 1.05524 0.62749 0.086 0.932
Likelihood ratio test=0.01 on 1 df, p=0.9318
n= 46, number of events= 12
============================
TCGA-COAD PRR5
[1] 151
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.05 0.4390 0.555
strata=LOW 34 9 9.95 0.0905 0.555
Chisq= 0.6 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5099 0.6005 0.6921 -0.737 0.461
Likelihood ratio test=0.5 on 1 df, p=0.4777
n= 46, number of events= 12
============================
TCGA-COAD CFL1
[1] 152
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 19 4 4.49 0.0533 0.0981
strata=LOW 27 8 7.51 0.0318 0.0981
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2032 1.2254 0.6500 0.313 0.755
Likelihood ratio test=0.1 on 1 df, p=0.7532
n= 46, number of events= 12
============================
TCGA-COAD MIR382
============================
TCGA-COAD LAMP2
[1] 153
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 17 3 3.53 0.0788 0.129
strata=LOW 29 9 8.47 0.0328 0.129
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2535 1.2885 0.7073 0.358 0.72
Likelihood ratio test=0.13 on 1 df, p=0.7164
n= 46, number of events= 12
============================
TCGA-COAD PTPN14
[1] 154
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 14 3 3.32 0.0312 0.0477
strata=LOW 32 9 8.68 0.0119 0.0477
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1520 1.1641 0.6965 0.218 0.827
Likelihood ratio test=0.05 on 1 df, p=0.8257
n= 46, number of events= 12
============================
TCGA-COAD AGPAT3
[1] 155
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 18 5 4.6 0.0354 0.0667
strata=LOW 28 7 7.4 0.0220 0.0667
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1649 0.8480 0.6390 -0.258 0.796
Likelihood ratio test=0.07 on 1 df, p=0.7964
n= 46, number of events= 12
============================
TCGA-COAD STING1
[1] 156
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 1 2.54 0.935 1.22
strata=LOW 35 11 9.46 0.251 1.22
Chisq= 1.2 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.103 3.014 1.050 1.051 0.293
Likelihood ratio test=1.49 on 1 df, p=0.2227
n= 46, number of events= 12
============================
TCGA-COAD ABCC1
[1] 157
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 3 3.16 0.00791 0.0112
strata=LOW 31 9 8.84 0.00282 0.0112
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.0720 1.0747 0.6803 0.106 0.916
Likelihood ratio test=0.01 on 1 df, p=0.9153
n= 46, number of events= 12
============================
TCGA-COAD IFNA5
============================
TCGA-COAD MIR140
[1] 158
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
n=21, 25 observations deleted due to missingness.
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 20 4 3.74 0.0180 0.278
strata=LOW 1 1 1.26 0.0534 0.278
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.811e+01 1.368e-08 1.623e+04 -0.001 0.999
Likelihood ratio test=0.54 on 1 df, p=0.4639
n= 21, number of events= 5
(25 observations deleted due to missingness)
============================
TCGA-COAD MYB
[1] 159
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 14 4 2.22 1.419 1.84
strata=LOW 32 8 9.78 0.323 1.84
Chisq= 1.8 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8530 0.4261 0.6485 -1.315 0.188
Likelihood ratio test=1.6 on 1 df, p=0.2064
n= 46, number of events= 12
============================
TCGA-COAD IFNA6
============================
TCGA-COAD IFNA14
============================
TCGA-COAD BDNF-AS
[1] 160
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 16 4 3.76 0.0158 0.0255
strata=LOW 30 8 8.24 0.0072 0.0255
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1033 0.9018 0.6477 -0.16 0.873
Likelihood ratio test=0.03 on 1 df, p=0.8737
n= 46, number of events= 12
============================
TCGA-COAD TRIB2
[1] 161
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 13 3 3.23 0.01648 0.0248
strata=LOW 33 9 8.77 0.00607 0.0248
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1096 1.1158 0.6961 0.157 0.875
Likelihood ratio test=0.03 on 1 df, p=0.8741
n= 46, number of events= 12
============================
TCGA-COAD MALAT1
[1] 162
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 18 4 4.92 0.171 0.316
strata=LOW 28 8 7.08 0.119 0.316
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3539 1.4247 0.6328 0.559 0.576
Likelihood ratio test=0.32 on 1 df, p=0.5708
n= 46, number of events= 12
============================
TCGA-COAD FH
[1] 163
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 13 2 3.04 0.357 0.521
strata=LOW 33 10 8.96 0.121 0.521
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5661 1.7614 0.7947 0.712 0.476
Likelihood ratio test=0.56 on 1 df, p=0.4531
n= 46, number of events= 12
============================
TCGA-COAD PEX10
[1] 164
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 8 1 1.64 0.2477 0.304
strata=LOW 38 11 10.36 0.0391 0.304
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.577 1.781 1.062 0.543 0.587
Likelihood ratio test=0.34 on 1 df, p=0.5584
n= 46, number of events= 12
============================
TCGA-COAD SCD
[1] 165
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 30 7 7.05 0.000295 0.000825
strata=LOW 16 5 4.95 0.000420 0.000825
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.01803 1.01820 0.62793 0.029 0.977
Likelihood ratio test=0 on 1 df, p=0.9771
n= 46, number of events= 12
============================
TCGA-COAD FTL
[1] 166
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 22 6 4.41 0.576 1.07
strata=LOW 24 6 7.59 0.334 1.07
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6777 0.5078 0.6654 -1.019 0.308
Likelihood ratio test=1.07 on 1 df, p=0.3007
n= 46, number of events= 12
============================
TCGA-COAD TSC1
[1] 167
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 14 3 2.89 0.00383 0.00521
strata=LOW 32 9 9.11 0.00122 0.00521
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.04897 0.95221 0.67834 -0.072 0.942
Likelihood ratio test=0.01 on 1 df, p=0.9427
n= 46, number of events= 12
============================
TCGA-COAD BRD3
[1] 168
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 9 2 2.1 0.00488 0.0062
strata=LOW 37 10 9.9 0.00104 0.0062
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.0624 1.0644 0.7923 0.079 0.937
Likelihood ratio test=0.01 on 1 df, p=0.9368
n= 46, number of events= 12
============================
TCGA-COAD SLC16A1
[1] 169
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 24 5 5.54 0.0530 0.123
strata=LOW 22 7 6.46 0.0454 0.123
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2258 1.2533 0.6439 0.351 0.726
Likelihood ratio test=0.12 on 1 df, p=0.7262
n= 46, number of events= 12
============================
TCGA-COAD MIR132
============================
TCGA-COAD MIR375
============================
TCGA-COAD MIOX
[1] 170
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
n=43, 3 observations deleted due to missingness.
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 34 10 9.65 0.0128 0.0671
strata=LOW 9 2 2.35 0.0525 0.0671
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2025 0.8167 0.7833 -0.259 0.796
Likelihood ratio test=0.07 on 1 df, p=0.7918
n= 43, number of events= 12
(3 observations deleted due to missingness)
============================
TCGA-COAD ATXN8OS
============================
TCGA-COAD KLHDC3
[1] 171
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 9 1 2.31 0.740 0.968
strata=LOW 37 11 9.69 0.176 0.968
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.9971 2.7105 1.0558 0.944 0.345
Likelihood ratio test=1.16 on 1 df, p=0.282
n= 46, number of events= 12
============================
TCGA-COAD MICU1
[1] 172
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 4 3.65 0.0345 0.0546
strata=LOW 31 8 8.35 0.0151 0.0546
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1510 0.8598 0.6471 -0.233 0.815
Likelihood ratio test=0.05 on 1 df, p=0.8165
n= 46, number of events= 12
============================
TCGA-COAD CBS
[1] 173
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 29 6 7.77 0.405 1.39
strata=LOW 17 6 4.23 0.745 1.39
Chisq= 1.4 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7032 2.0203 0.6084 1.156 0.248
Likelihood ratio test=1.28 on 1 df, p=0.2571
n= 46, number of events= 12
============================
TCGA-COAD HUWE1
[1] 174
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 2 3.85 0.893 1.38
strata=LOW 31 10 8.15 0.422 1.38
Chisq= 1.4 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8911 2.4377 0.7832 1.138 0.255
Likelihood ratio test=1.54 on 1 df, p=0.2151
n= 46, number of events= 12
============================
TCGA-COAD LINC00472
[1] 175
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 37 10 9.76 0.0057 0.0314
strata=LOW 9 2 2.24 0.0249 0.0314
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1386 0.8705 0.7834 -0.177 0.86
Likelihood ratio test=0.03 on 1 df, p=0.8575
n= 46, number of events= 12
============================
TCGA-COAD FGF21
[1] 176
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
n=11, 35 observations deleted due to missingness.
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 10 2 1.675 0.0631 0.392
strata=LOW 1 0 0.325 0.3250 0.392
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.930e+01 4.137e-09 2.481e+04 -0.001 0.999
Likelihood ratio test=0.71 on 1 df, p=0.3983
n= 11, number of events= 2
(35 observations deleted due to missingness)
============================
TCGA-COAD MIR34A
============================
TCGA-COAD IDH1
[1] 177
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 17 5 4.16 0.1689 0.293
strata=LOW 29 7 7.84 0.0897 0.293
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3429 0.7097 0.6367 -0.539 0.59
Likelihood ratio test=0.29 on 1 df, p=0.591
n= 46, number of events= 12
============================
TCGA-COAD GSK3B
[1] 178
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 14 3 3.11 0.00367 0.00542
strata=LOW 32 9 8.89 0.00128 0.00542
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.05127 1.05261 0.69651 0.074 0.941
Likelihood ratio test=0.01 on 1 df, p=0.9411
n= 46, number of events= 12
============================
TCGA-COAD KDM4A
[1] 179
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 20 4 4.35 0.0276 0.0508
strata=LOW 26 8 7.65 0.0156 0.0508
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1483 1.1598 0.6581 0.225 0.822
Likelihood ratio test=0.05 on 1 df, p=0.8211
n= 46, number of events= 12
============================
TCGA-COAD PEX12
[1] 180
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.71 0.1849 0.258
strata=LOW 35 10 9.29 0.0539 0.258
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4013 1.4937 0.7956 0.504 0.614
Likelihood ratio test=0.27 on 1 df, p=0.6006
n= 46, number of events= 12
============================
TCGA-COAD IDO1
[1] 181
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 23 8 5.36 1.30 2.71
strata=LOW 23 4 6.64 1.05 2.71
Chisq= 2.7 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.0107 0.3640 0.6376 -1.585 0.113
Likelihood ratio test=2.65 on 1 df, p=0.1037
n= 46, number of events= 12
============================
TCGA-COAD BCAT2
[1] 182
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 16 2 4.08 1.058 1.86
strata=LOW 30 10 7.92 0.545 1.86
Chisq= 1.9 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.0411 2.8324 0.7978 1.305 0.192
Likelihood ratio test=2.02 on 1 df, p=0.1549
n= 46, number of events= 12
============================
TCGA-COAD ADAM23
[1] 183
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 21 6 5.22 0.1174 0.225
strata=LOW 25 6 6.78 0.0903 0.225
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2870 0.7505 0.6075 -0.472 0.637
Likelihood ratio test=0.22 on 1 df, p=0.6357
n= 46, number of events= 12
============================
TCGA-COAD PEX3
[1] 184
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 9 2 1.93 0.002815 0.00351
strata=LOW 37 10 10.07 0.000538 0.00351
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.04701 0.95408 0.79343 -0.059 0.953
Likelihood ratio test=0 on 1 df, p=0.953
n= 46, number of events= 12
============================
TCGA-COAD ATP5MC3
[1] 185
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 3 3.93 0.219 0.365
strata=LOW 31 9 8.07 0.106 0.365
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4167 1.5170 0.6943 0.6 0.548
Likelihood ratio test=0.38 on 1 df, p=0.5386
n= 46, number of events= 12
============================
TCGA-COAD AQP5
[1] 186
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 33 9 8.22 0.0734 0.295
strata=LOW 13 3 3.78 0.1598 0.295
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4243 0.6542 0.7867 -0.539 0.59
Likelihood ratio test=0.32 on 1 df, p=0.5736
n= 46, number of events= 12
============================
TCGA-COAD ADAMTS9-AS1
[1] 187
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 39 12 9.99 0.406 2.47
strata=LOW 7 0 2.01 2.013 2.47
Chisq= 2.5 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.933e+01 4.021e-09 1.003e+04 -0.002 0.998
Likelihood ratio test=4.45 on 1 df, p=0.0348
n= 46, number of events= 12
============================
TCGA-COAD ACSL3
[1] 188
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.77 0.2140 0.3
strata=LOW 34 10 9.23 0.0642 0.3
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4317 1.5399 0.7944 0.543 0.587
Likelihood ratio test=0.32 on 1 df, p=0.5715
n= 46, number of events= 12
============================
TCGA-COAD DDR2
[1] 189
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 33 10 9.32 0.0494 0.23
strata=LOW 13 2 2.68 0.1719 0.23
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3745 0.6877 0.7854 -0.477 0.634
Likelihood ratio test=0.25 on 1 df, p=0.6205
n= 46, number of events= 12
============================
TCGA-COAD TERT
[1] 190
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 17 6 3.49 1.801 2.66
strata=LOW 29 6 8.51 0.739 2.66
Chisq= 2.7 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.9570 0.3840 0.6089 -1.572 0.116
Likelihood ratio test=2.45 on 1 df, p=0.1174
n= 46, number of events= 12
============================
TCGA-COAD IFNA7
============================
TCGA-COAD ECH1
[1] 191
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 17 4 4.97 0.188 0.353
strata=LOW 29 8 7.03 0.132 0.353
Chisq= 0.4 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3752 1.4553 0.6350 0.591 0.555
Likelihood ratio test=0.36 on 1 df, p=0.5494
n= 46, number of events= 12
============================
TCGA-COAD CS
[1] 192
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.89 0.277 0.396
strata=LOW 34 10 9.11 0.088 0.396
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4953 1.6410 0.7952 0.623 0.533
Likelihood ratio test=0.43 on 1 df, p=0.5144
n= 46, number of events= 12
============================
TCGA-COAD AMN
[1] 193
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 36 8 8.96 0.103 0.584
strata=LOW 10 4 3.04 0.305 0.584
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5251 1.6906 0.6943 0.756 0.449
Likelihood ratio test=0.53 on 1 df, p=0.4675
n= 46, number of events= 12
============================
TCGA-COAD DUOX2
[1] 194
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 30 8 7.92 0.000861 0.00315
strata=LOW 16 4 4.08 0.001669 0.00315
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.03846 0.96227 0.68532 -0.056 0.955
Likelihood ratio test=0 on 1 df, p=0.9551
n= 46, number of events= 12
============================
TCGA-COAD MBOAT1
[1] 195
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 23 4 5.42 0.372 0.768
strata=LOW 23 8 6.58 0.307 0.768
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5526 1.7377 0.6379 0.866 0.386
Likelihood ratio test=0.78 on 1 df, p=0.3783
n= 46, number of events= 12
============================
TCGA-COAD RNF113A
[1] 196
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 9 2 1.61 0.0934 0.115
strata=LOW 37 10 10.39 0.0145 0.115
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2733 0.7608 0.8080 -0.338 0.735
Likelihood ratio test=0.11 on 1 df, p=0.7415
n= 46, number of events= 12
============================
TCGA-COAD MIR138-1
============================
TCGA-COAD MIR144
============================
TCGA-COAD P4HB
[1] 197
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 9 2 2.14 0.00861 0.0111
strata=LOW 37 10 9.86 0.00186 0.0111
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.08357 1.08716 0.79463 0.105 0.916
Likelihood ratio test=0.01 on 1 df, p=0.9156
n= 46, number of events= 12
============================
TCGA-COAD MIR338
============================
TCGA-COAD PTGS2
[1] 198
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 23 6 6.38 0.0226 0.0528
strata=LOW 23 6 5.62 0.0256 0.0528
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1395 1.1497 0.6076 0.23 0.818
Likelihood ratio test=0.05 on 1 df, p=0.8181
n= 46, number of events= 12
============================
TCGA-COAD ASAH2
[1] 199
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 14 2 3.42 0.587 0.902
strata=LOW 32 10 8.58 0.234 0.902
Chisq= 0.9 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7373 2.0903 0.7937 0.929 0.353
Likelihood ratio test=0.99 on 1 df, p=0.3207
n= 46, number of events= 12
============================
TCGA-COAD MIR522
============================
TCGA-COAD GALNT14
[1] 200
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 21 5 6.89 0.519 1.31
strata=LOW 25 7 5.11 0.700 1.31
Chisq= 1.3 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7058 2.0255 0.6284 1.123 0.261
Likelihood ratio test=1.32 on 1 df, p=0.2508
n= 46, number of events= 12
============================
TCGA-COAD KDM4C
[1] 201
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 5 3.42 0.731 1.12
strata=LOW 31 7 8.58 0.291 1.12
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6585 0.5176 0.6343 -1.038 0.299
Likelihood ratio test=1.06 on 1 df, p=0.3034
n= 46, number of events= 12
============================
TCGA-COAD FXN
[1] 202
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 9 2 2.04 0.000845 0.00107
strata=LOW 37 10 9.96 0.000173 0.00107
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.02585 1.02618 0.79188 0.033 0.974
Likelihood ratio test=0 on 1 df, p=0.9739
n= 46, number of events= 12
============================
TCGA-COAD MEF2C
[1] 203
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 28 7 6.73 0.011 0.0284
strata=LOW 18 5 5.27 0.014 0.0284
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1060 0.8995 0.6287 -0.169 0.866
Likelihood ratio test=0.03 on 1 df, p=0.8656
n= 46, number of events= 12
============================
TCGA-COAD MDM2
[1] 204
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 18 3 3.73 0.1431 0.237
strata=LOW 28 9 8.27 0.0645 0.237
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3399 1.4048 0.7010 0.485 0.628
Likelihood ratio test=0.24 on 1 df, p=0.6212
n= 46, number of events= 12
============================
TCGA-COAD MAP3K14
[1] 205
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.61 0.1440 0.197
strata=LOW 35 10 9.39 0.0401 0.197
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3508 1.4203 0.7941 0.442 0.659
Likelihood ratio test=0.21 on 1 df, p=0.6479
n= 46, number of events= 12
============================
TCGA-COAD MDM4
[1] 206
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 2.38 1.107 1.46
strata=LOW 34 8 9.62 0.274 1.46
Chisq= 1.5 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7643 0.4657 0.6478 -1.18 0.238
Likelihood ratio test=1.3 on 1 df, p=0.2547
n= 46, number of events= 12
============================
TCGA-COAD ASMTL-AS1
[1] 207
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 19 5 4.82 0.00688 0.0131
strata=LOW 27 7 7.18 0.00462 0.0131
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.0718 0.9307 0.6265 -0.115 0.909
Likelihood ratio test=0.01 on 1 df, p=0.9089
n= 46, number of events= 12
============================
TCGA-COAD NEAT1
[1] 208
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 21 4 4.62 0.0823 0.142
strata=LOW 25 8 7.38 0.0514 0.142
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2358 1.2660 0.6273 0.376 0.707
Likelihood ratio test=0.14 on 1 df, p=0.7043
n= 46, number of events= 12
============================
TCGA-COAD COPZ1
[1] 209
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 6 2 1.05 0.8481 0.956
strata=LOW 40 10 10.95 0.0817 0.956
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7611 0.4672 0.7969 -0.955 0.34
Likelihood ratio test=0.78 on 1 df, p=0.3766
n= 46, number of events= 12
============================
TCGA-COAD PLIN2
[1] 210
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 16 4 2.83 0.483 0.713
strata=LOW 30 8 9.17 0.149 0.713
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5634 0.5693 0.6759 -0.834 0.405
Likelihood ratio test=0.67 on 1 df, p=0.4119
n= 46, number of events= 12
============================
TCGA-COAD FADS2
[1] 211
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 20 4 4.64 0.0888 0.154
strata=LOW 26 8 7.36 0.0561 0.154
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2453 1.2780 0.6270 0.391 0.696
Likelihood ratio test=0.16 on 1 df, p=0.6927
n= 46, number of events= 12
============================
TCGA-COAD MIR7-1
============================
TCGA-COAD TXN
[1] 212
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 3 3.69 0.130 0.208
strata=LOW 31 9 8.31 0.058 0.208
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3149 1.3701 0.6926 0.455 0.649
Likelihood ratio test=0.21 on 1 df, p=0.6431
n= 46, number of events= 12
============================
TCGA-COAD MIR302A
============================
TCGA-COAD EGLN2
[1] 213
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 3 3.29 0.02560 0.0368
strata=LOW 31 9 8.71 0.00967 0.0368
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1301 1.1389 0.6789 0.192 0.848
Likelihood ratio test=0.04 on 1 df, p=0.8466
n= 46, number of events= 12
============================
TCGA-COAD NCOA3
[1] 214
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 21 5 3.92 0.295 0.509
strata=LOW 25 7 8.08 0.143 0.509
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4604 0.6310 0.6506 -0.708 0.479
Likelihood ratio test=0.5 on 1 df, p=0.4801
n= 46, number of events= 12
============================
TCGA-COAD SREBF1
[1] 215
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 10 1 3.13 1.449 2.04
strata=LOW 36 11 8.87 0.511 2.04
Chisq= 2 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.385 3.996 1.050 1.32 0.187
Likelihood ratio test=2.52 on 1 df, p=0.1125
n= 46, number of events= 12
============================
TCGA-COAD LINC01134
[1] 216
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 18 7 3.8 2.69 4.47
strata=LOW 28 5 8.2 1.25 4.47
Chisq= 4.5 on 1 degrees of freedom, p= 0.03
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.3915 0.2487 0.7074 -1.967 0.0492
Likelihood ratio test=4.35 on 1 df, p=0.037
n= 46, number of events= 12
============================
TCGA-COAD MYCN
[1] 217
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 19 1 4.4 2.63 4.4
strata=LOW 27 11 7.6 1.52 4.4
Chisq= 4.4 on 1 degrees of freedom, p= 0.04
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.902 6.697 1.049 1.812 0.0699
Likelihood ratio test=5.37 on 1 df, p=0.02054
n= 46, number of events= 12
============================
TCGA-COAD IFNA4
============================
TCGA-COAD DPEP1
[1] 218
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 41 11 11.264 0.0062 0.104
strata=LOW 5 1 0.736 0.0950 0.104
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.341 1.406 1.063 0.321 0.748
Likelihood ratio test=0.09 on 1 df, p=0.7588
n= 46, number of events= 12
============================
TCGA-COAD VDAC2
[1] 219
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 17 4 4.56 0.0688 0.12
strata=LOW 29 8 7.44 0.0422 0.12
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2188 1.2446 0.6327 0.346 0.73
Likelihood ratio test=0.12 on 1 df, p=0.7273
n= 46, number of events= 12
============================
TCGA-COAD PCBP2-OT1
[1] 220
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
n=40, 6 observations deleted due to missingness.
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 28 6 5.51 0.0433 0.148
strata=LOW 12 3 3.49 0.0684 0.148
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3229 0.7240 0.8421 -0.383 0.701
Likelihood ratio test=0.15 on 1 df, p=0.6945
n= 40, number of events= 9
(6 observations deleted due to missingness)
============================
TCGA-COAD KEAP1
[1] 221
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 7 1 1.93 0.4455 0.556
strata=LOW 39 11 10.07 0.0852 0.556
Chisq= 0.6 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7683 2.1562 1.0561 0.728 0.467
Likelihood ratio test=0.65 on 1 df, p=0.4209
n= 46, number of events= 12
============================
TCGA-COAD RPL8
[1] 222
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 14 1 3.29 1.595 2.33
strata=LOW 32 11 8.71 0.603 2.33
Chisq= 2.3 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.471 4.355 1.053 1.398 0.162
Likelihood ratio test=2.87 on 1 df, p=0.09032
n= 46, number of events= 12
============================
TCGA-COAD ALOX12
[1] 223
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 16 2 3.6 0.714 1.15
strata=LOW 30 10 8.4 0.307 1.15
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8296 2.2925 0.7964 1.042 0.298
Likelihood ratio test=1.25 on 1 df, p=0.2629
n= 46, number of events= 12
============================
TCGA-COAD ACSF2
[1] 224
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 31 7 7.23 0.00708 0.0214
strata=LOW 15 5 4.77 0.01072 0.0214
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.09352 1.09803 0.63878 0.146 0.884
Likelihood ratio test=0.02 on 1 df, p=0.8841
n= 46, number of events= 12
============================
TCGA-COAD KDM5A
[1] 225
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 17 3 3.78 0.1620 0.251
strata=LOW 29 9 8.22 0.0746 0.251
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3394 1.4040 0.6811 0.498 0.618
Likelihood ratio test=0.26 on 1 df, p=0.6101
n= 46, number of events= 12
============================
TCGA-COAD NRAS
[1] 226
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 16 4 3.46 0.0827 0.127
strata=LOW 30 8 8.54 0.0336 0.127
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2300 0.7945 0.6469 -0.356 0.722
Likelihood ratio test=0.12 on 1 df, p=0.7244
n= 46, number of events= 12
============================
TCGA-COAD MIR30E
============================
TCGA-COAD OGFRP1
[1] 227
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 4 3.83 0.00768 0.0141
strata=LOW 34 8 8.17 0.00360 0.0141
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.08058 0.92258 0.67915 -0.119 0.906
Likelihood ratio test=0.01 on 1 df, p=0.9061
n= 46, number of events= 12
============================
TCGA-COAD TF
[1] 228
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 32 7 8.32 0.208 0.715
strata=LOW 14 5 3.68 0.471 0.715
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5104 1.6659 0.6097 0.837 0.403
Likelihood ratio test=0.68 on 1 df, p=0.4083
n= 46, number of events= 12
============================
TCGA-COAD ETV4
[1] 229
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 44 12 11.683 0.00861 0.33
strata=LOW 2 0 0.317 0.31718 0.33
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.706e+01 3.888e-08 8.828e+03 -0.002 0.998
Likelihood ratio test=0.65 on 1 df, p=0.4212
n= 46, number of events= 12
============================
TCGA-COAD PLA2G6
[1] 230
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 14 4 3.54 0.0611 0.0951
strata=LOW 32 8 8.46 0.0255 0.0951
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1995 0.8192 0.6477 -0.308 0.758
Likelihood ratio test=0.09 on 1 df, p=0.7598
n= 46, number of events= 12
============================
TCGA-COAD POR
[1] 231
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.18 0.3093 0.411
strata=LOW 34 9 9.82 0.0686 0.411
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4511 0.6369 0.7098 -0.635 0.525
Likelihood ratio test=0.38 on 1 df, p=0.5365
n= 46, number of events= 12
============================
TCGA-COAD BRPF1
[1] 232
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 10 2 2.39 0.0631 0.0834
strata=LOW 36 10 9.61 0.0157 0.0834
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2285 1.2567 0.7928 0.288 0.773
Likelihood ratio test=0.09 on 1 df, p=0.7683
n= 46, number of events= 12
============================
TCGA-COAD TMBIM4
[1] 233
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 4 3.33 0.136 0.204
strata=LOW 31 8 8.67 0.052 0.204
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2910 0.7475 0.6466 -0.45 0.653
Likelihood ratio test=0.2 on 1 df, p=0.6563
n= 46, number of events= 12
============================
TCGA-COAD KRAS
[1] 234
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 3 3.29 0.02598 0.0389
strata=LOW 31 9 8.71 0.00982 0.0389
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1363 1.1460 0.6915 0.197 0.844
Likelihood ratio test=0.04 on 1 df, p=0.8424
n= 46, number of events= 12
============================
TCGA-COAD AHCY
[1] 235
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 20 5 5.05 0.000564 0.00113
strata=LOW 26 7 6.95 0.000411 0.00113
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.02114 1.02137 0.63011 0.034 0.973
Likelihood ratio test=0 on 1 df, p=0.9732
n= 46, number of events= 12
============================
TCGA-COAD MIR34C
============================
TCGA-COAD ATG3
[1] 236
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 8 2 1.63 0.0859 0.103
strata=LOW 38 10 10.37 0.0135 0.103
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2535 0.7761 0.7922 -0.32 0.749
Likelihood ratio test=0.1 on 1 df, p=0.7551
n= 46, number of events= 12
============================
TCGA-COAD MIR30B
============================
TCGA-COAD LYRM1
[1] 237
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.7 0.0245 0.0448
strata=LOW 35 8 8.3 0.0109 0.0448
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1435 0.8664 0.6787 -0.211 0.833
Likelihood ratio test=0.04 on 1 df, p=0.8344
n= 46, number of events= 12
============================
TCGA-COAD SIRT6
[1] 238
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 18 3 4.94 0.762 1.43
strata=LOW 28 9 7.06 0.533 1.43
Chisq= 1.4 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.797 2.219 0.684 1.165 0.244
Likelihood ratio test=1.49 on 1 df, p=0.2219
n= 46, number of events= 12
============================
TCGA-COAD KMT2D
[1] 239
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 16 3 3.46 0.0620 0.0913
strata=LOW 30 9 8.54 0.0252 0.0913
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2051 1.2276 0.6797 0.302 0.763
Likelihood ratio test=0.09 on 1 df, p=0.7595
n= 46, number of events= 12
============================
TCGA-COAD LPIN1
[1] 240
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 14 2 3.85 0.893 1.38
strata=LOW 32 10 8.15 0.422 1.38
Chisq= 1.4 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8911 2.4377 0.7832 1.138 0.255
Likelihood ratio test=1.54 on 1 df, p=0.2151
n= 46, number of events= 12
============================
TCGA-COAD MBOAT2
[1] 241
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 18 3 4.09 0.291 0.498
strata=LOW 28 9 7.91 0.150 0.498
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4851 1.6243 0.6937 0.699 0.484
Likelihood ratio test=0.52 on 1 df, p=0.4722
n= 46, number of events= 12
============================
TCGA-COAD KDM3B
[1] 242
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 13 3 2.81 0.01333 0.0188
strata=LOW 33 9 9.19 0.00407 0.0188
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.09516 0.90923 0.69478 -0.137 0.891
Likelihood ratio test=0.02 on 1 df, p=0.8917
n= 46, number of events= 12
============================
TCGA-COAD ARHGEF26-AS1
[1] 243
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 35 10 10.27 0.00687 0.0508
strata=LOW 11 2 1.73 0.04066 0.0508
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1814 1.1989 0.8058 0.225 0.822
Likelihood ratio test=0.05 on 1 df, p=0.8248
n= 46, number of events= 12
============================
TCGA-COAD MIR9-1
============================
TCGA-COAD AIFM2
[1] 244
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 1 2.93 1.275 1.84
strata=LOW 35 11 9.07 0.412 1.84
Chisq= 1.8 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.333 3.793 1.057 1.261 0.207
Likelihood ratio test=2.23 on 1 df, p=0.1353
n= 46, number of events= 12
============================
TCGA-COAD PRDX1
[1] 245
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 13 1 2.84 1.191 1.7
strata=LOW 33 11 9.16 0.369 1.7
Chisq= 1.7 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.289 3.630 1.058 1.218 0.223
Likelihood ratio test=2.06 on 1 df, p=0.1512
n= 46, number of events= 12
============================
TCGA-COAD FOXO4
[1] 246
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 23 4 5.01 0.202 0.414
strata=LOW 23 8 6.99 0.145 0.414
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4164 1.5164 0.6517 0.639 0.523
Likelihood ratio test=0.42 on 1 df, p=0.5189
n= 46, number of events= 12
============================
TCGA-COAD BMAL1
[1] 247
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 21 7 4.7 1.124 2.01
strata=LOW 25 5 7.3 0.724 2.01
Chisq= 2 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8761 0.4164 0.6367 -1.376 0.169
Likelihood ratio test=1.99 on 1 df, p=0.158
n= 46, number of events= 12
============================
TCGA-COAD MIR127
============================
TCGA-COAD TGFBR1
[1] 248
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 10 1 2.38 0.804 1.07
strata=LOW 36 11 9.62 0.199 1.07
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.044 2.840 1.057 0.988 0.323
Likelihood ratio test=1.28 on 1 df, p=0.2579
n= 46, number of events= 12
============================
TCGA-COAD NR1D2
[1] 249
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 18 4 3.57 0.0510 0.0802
strata=LOW 28 8 8.43 0.0216 0.0802
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1835 0.8324 0.6489 -0.283 0.777
Likelihood ratio test=0.08 on 1 df, p=0.7788
n= 46, number of events= 12
============================
TCGA-COAD FZD7
[1] 250
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 19 6 4.38 0.596 1.01
strata=LOW 27 6 7.62 0.343 1.01
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6059 0.5456 0.6123 -0.989 0.322
Likelihood ratio test=0.98 on 1 df, p=0.3212
n= 46, number of events= 12
============================
TCGA-COAD G6PD
[1] 251
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 10 1 4.2 2.44 4.55
strata=LOW 36 11 7.8 1.31 4.55
Chisq= 4.6 on 1 degrees of freedom, p= 0.03
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.958e+01 3.191e+08 8.354e+03 0.002 0.998
Likelihood ratio test=7.6 on 1 df, p=0.005825
n= 46, number of events= 12
============================
TCGA-COAD HRAS
[1] 252
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 5 0 1.42 1.415 1.68
strata=LOW 41 12 10.58 0.189 1.68
Chisq= 1.7 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.928e+01 2.360e+08 1.184e+04 0.002 0.999
Likelihood ratio test=3.08 on 1 df, p=0.07905
n= 46, number of events= 12
============================
TCGA-COAD SLC38A1
[1] 253
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 14 2 3.19 0.443 0.665
strata=LOW 32 10 8.81 0.160 0.665
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6391 1.8947 0.7965 0.802 0.422
Likelihood ratio test=0.72 on 1 df, p=0.3955
n= 46, number of events= 12
============================
TCGA-COAD SLC39A14
[1] 254
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 4 3.75 0.01622 0.0261
strata=LOW 31 8 8.25 0.00738 0.0261
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1047 0.9006 0.6479 -0.162 0.872
Likelihood ratio test=0.03 on 1 df, p=0.8721
n= 46, number of events= 12
============================
TCGA-COAD MIR21
============================
TCGA-COAD MIR1-1
============================
TCGA-COAD PROM2
[1] 255
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 33 10 8.72 0.189 0.758
strata=LOW 13 2 3.28 0.502 0.758
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6874 0.5029 0.8026 -0.857 0.392
Likelihood ratio test=0.83 on 1 df, p=0.3614
n= 46, number of events= 12
============================
TCGA-COAD NFE2L2
[1] 256
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 16 4 3.44 0.0925 0.141
strata=LOW 30 8 8.56 0.0371 0.141
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2427 0.7845 0.6467 -0.375 0.707
Likelihood ratio test=0.14 on 1 df, p=0.71
n= 46, number of events= 12
============================
TCGA-COAD GABARAPL1
[1] 257
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 19 4 4.36 0.0294 0.0496
strata=LOW 27 8 7.64 0.0168 0.0496
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1405 1.1509 0.6318 0.222 0.824
Likelihood ratio test=0.05 on 1 df, p=0.823
n= 46, number of events= 12
============================
TCGA-COAD MIR335
============================
TCGA-COAD PTEN
[1] 258
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 18 4 4.22 0.01119 0.0196
strata=LOW 28 8 7.78 0.00606 0.0196
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.09071 1.09495 0.64888 0.14 0.889
Likelihood ratio test=0.02 on 1 df, p=0.8885
n= 46, number of events= 12
============================
TCGA-COAD PARP4
[1] 259
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 18 5 3.36 0.803 1.24
strata=LOW 28 7 8.64 0.312 1.24
Chisq= 1.2 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7048 0.4942 0.6444 -1.094 0.274
Likelihood ratio test=1.18 on 1 df, p=0.2779
n= 46, number of events= 12
============================
TCGA-COAD MS4A15
[1] 260
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 34 9 10.4 0.189 1.53
strata=LOW 12 3 1.6 1.232 1.53
Chisq= 1.5 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8670 2.3798 0.7218 1.201 0.23
Likelihood ratio test=1.3 on 1 df, p=0.2548
n= 46, number of events= 12
============================
TCGA-COAD TIMM9
[1] 261
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 10 2 2.16 0.01118 0.0144
strata=LOW 36 10 9.84 0.00245 0.0144
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.0951 1.0998 0.7936 0.12 0.905
Likelihood ratio test=0.01 on 1 df, p=0.9037
n= 46, number of events= 12
============================
TCGA-COAD PARP3
[1] 262
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 9 3 2.43 0.134 0.173
strata=LOW 37 9 9.57 0.034 0.173
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2811 0.7549 0.6790 -0.414 0.679
Likelihood ratio test=0.16 on 1 df, p=0.6855
n= 46, number of events= 12
============================
TCGA-COAD WIPI1
[1] 263
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 20 6 5.65 0.0219 0.0472
strata=LOW 26 6 6.35 0.0195 0.0472
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1331 0.8754 0.6131 -0.217 0.828
Likelihood ratio test=0.05 on 1 df, p=0.8285
n= 46, number of events= 12
============================
TCGA-COAD SNX5
[1] 264
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 14 3 3.32 0.0317 0.049
strata=LOW 32 9 8.68 0.0122 0.049
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1547 1.1673 0.6997 0.221 0.825
Likelihood ratio test=0.05 on 1 df, p=0.8234
n= 46, number of events= 12
============================
TCGA-COAD LINC00239
[1] 265
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 18 5 6.31 0.273 0.634
strata=LOW 28 7 5.69 0.303 0.634
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4967 1.6433 0.6301 0.788 0.43
Likelihood ratio test=0.64 on 1 df, p=0.4223
n= 46, number of events= 12
============================
TCGA-COAD PIEZO1
[1] 266
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 3 3.36 0.0387 0.056
strata=LOW 31 9 8.64 0.0150 0.056
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1605 1.1741 0.6788 0.236 0.813
Likelihood ratio test=0.06 on 1 df, p=0.811
n= 46, number of events= 12
============================
TCGA-COAD AKR1C2
[1] 267
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 37 10 10.36 0.0123 0.0952
strata=LOW 9 2 1.64 0.0772 0.0952
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2478 1.2812 0.8052 0.308 0.758
Likelihood ratio test=0.09 on 1 df, p=0.7637
n= 46, number of events= 12
============================
TCGA-COAD MIR4443
============================
TCGA-COAD SLC16A1-AS1
[1] 268
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 24 3 5.16 0.905 1.73
strata=LOW 22 9 6.84 0.683 1.73
Chisq= 1.7 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8699 2.3867 0.6814 1.277 0.202
Likelihood ratio test=1.81 on 1 df, p=0.1785
n= 46, number of events= 12
============================
TCGA-COAD FAR1
[1] 269
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 13 2 3.04 0.357 0.521
strata=LOW 33 10 8.96 0.121 0.521
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5661 1.7614 0.7947 0.712 0.476
Likelihood ratio test=0.56 on 1 df, p=0.4531
n= 46, number of events= 12
============================
TCGA-COAD CISD2
[1] 270
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 3.02 0.347 0.507
strata=LOW 34 10 8.98 0.117 0.507
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5594 1.7497 0.7957 0.703 0.482
Likelihood ratio test=0.55 on 1 df, p=0.4594
n= 46, number of events= 12
============================
TCGA-COAD MAPK3
[1] 271
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 22 5 5.47 0.0398 0.0828
strata=LOW 24 7 6.53 0.0333 0.0828
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1778 1.1946 0.6187 0.287 0.774
Likelihood ratio test=0.08 on 1 df, p=0.7735
n= 46, number of events= 12
============================
TCGA-COAD CYGB
[1] 272
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 22 5 5.3 0.0171 0.0332
strata=LOW 24 7 6.7 0.0135 0.0332
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1107 1.1171 0.6079 0.182 0.855
Likelihood ratio test=0.03 on 1 df, p=0.8552
n= 46, number of events= 12
============================
TCGA-COAD MLST8
[1] 273
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 4 0 1.04 1.0358 1.18
strata=LOW 42 12 10.96 0.0978 1.18
Chisq= 1.2 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.820e+01 8.043e+07 8.269e+03 0.002 0.998
Likelihood ratio test=2.21 on 1 df, p=0.1375
n= 46, number of events= 12
============================
TCGA-COAD PANX2
[1] 274
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 23 6 6.79 0.0927 0.232
strata=LOW 23 6 5.21 0.1209 0.232
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2922 1.3394 0.6087 0.48 0.631
Likelihood ratio test=0.23 on 1 df, p=0.6303
n= 46, number of events= 12
============================
TCGA-COAD PEBP1
[1] 275
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 9 1 2.47 0.875 1.17
strata=LOW 37 11 9.53 0.227 1.17
Chisq= 1.2 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.089 2.971 1.056 1.031 0.302
Likelihood ratio test=1.41 on 1 df, p=0.2349
n= 46, number of events= 12
============================
TCGA-COAD PARP8
[1] 276
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 3 3.45 0.0585 0.0915
strata=LOW 31 9 8.55 0.0236 0.0915
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2106 1.2344 0.6973 0.302 0.763
Likelihood ratio test=0.09 on 1 df, p=0.7598
n= 46, number of events= 12
============================
TCGA-COAD GJA1
[1] 277
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.26 0.2386 0.31
strata=LOW 35 9 9.74 0.0555 0.31
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3835 0.6815 0.6926 -0.554 0.58
Likelihood ratio test=0.29 on 1 df, p=0.59
n= 46, number of events= 12
============================
TCGA-COAD BAP1
[1] 278
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 7 1 2.05 0.539 0.681
strata=LOW 39 11 9.95 0.111 0.681
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8459 2.3300 1.0555 0.801 0.423
Likelihood ratio test=0.8 on 1 df, p=0.3704
n= 46, number of events= 12
============================
TCGA-COAD MAP3K11
[1] 279
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 17 4 4.49 0.0533 0.0981
strata=LOW 29 8 7.51 0.0318 0.0981
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2032 1.2254 0.6500 0.313 0.755
Likelihood ratio test=0.1 on 1 df, p=0.7532
n= 46, number of events= 12
============================
TCGA-COAD TTBK2
[1] 280
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 22 4 5.62 0.468 1.01
strata=LOW 24 8 6.38 0.413 1.01
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6342 1.8856 0.6400 0.991 0.322
Likelihood ratio test=1.02 on 1 df, p=0.3129
n= 46, number of events= 12
============================
TCGA-COAD MIR214
============================
TCGA-COAD PARP15
[1] 281
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 25 6 4.94 0.227 0.434
strata=LOW 21 6 7.06 0.159 0.434
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4082 0.6648 0.6233 -0.655 0.513
Likelihood ratio test=0.43 on 1 df, p=0.511
n= 46, number of events= 12
============================
TCGA-COAD HDDC3
[1] 282
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 5 1 1.21 0.03697 0.043
strata=LOW 41 11 10.79 0.00415 0.043
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2201 1.2462 1.0636 0.207 0.836
Likelihood ratio test=0.05 on 1 df, p=0.8314
n= 46, number of events= 12
============================
TCGA-COAD MIR10A
============================
TCGA-COAD CGAS
[1] 283
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 21 5 3.8 0.382 0.592
strata=LOW 25 7 8.2 0.177 0.592
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4656 0.6277 0.6107 -0.763 0.446
Likelihood ratio test=0.57 on 1 df, p=0.4506
n= 46, number of events= 12
============================
TCGA-COAD SIRT2
[1] 284
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 13 2 2.6 0.1370 0.188
strata=LOW 33 10 9.4 0.0378 0.188
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3426 1.4086 0.7949 0.431 0.666
Likelihood ratio test=0.2 on 1 df, p=0.6562
n= 46, number of events= 12
============================
TCGA-COAD PPARD
[1] 285
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 23 5 5.48 0.0419 0.0961
strata=LOW 23 7 6.52 0.0352 0.0961
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1992 1.2204 0.6433 0.31 0.757
Likelihood ratio test=0.1 on 1 df, p=0.7571
n= 46, number of events= 12
============================
TCGA-COAD EGR1
[1] 286
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 20 6 6.69 0.0710 0.174
strata=LOW 26 6 5.31 0.0894 0.174
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2526 1.2874 0.6073 0.416 0.677
Likelihood ratio test=0.17 on 1 df, p=0.6767
n= 46, number of events= 12
============================
TCGA-COAD AQP3
[1] 287
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 24 7 7.54 0.0388 0.111
strata=LOW 22 5 4.46 0.0655 0.111
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2022 1.2241 0.6079 0.333 0.739
Likelihood ratio test=0.11 on 1 df, p=0.7404
n= 46, number of events= 12
============================
TCGA-COAD HSF1
[1] 288
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 9 0 2.82 2.816 3.81
strata=LOW 37 12 9.18 0.863 3.81
Chisq= 3.8 on 1 degrees of freedom, p= 0.05
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.949e+01 2.926e+08 8.752e+03 0.002 0.998
Likelihood ratio test=6.53 on 1 df, p=0.0106
n= 46, number of events= 12
============================
TCGA-COAD MIR18A
============================
TCGA-COAD OSBPL9
[1] 289
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 14 2 2.88 0.2678 0.382
strata=LOW 32 10 9.12 0.0845 0.382
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4865 1.6265 0.7949 0.612 0.541
Likelihood ratio test=0.41 on 1 df, p=0.5221
n= 46, number of events= 12
============================
TCGA-COAD SESN2
[1] 290
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 27 5 6.25 0.249 0.622
strata=LOW 19 7 5.75 0.270 0.622
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4887 1.6301 0.6247 0.782 0.434
Likelihood ratio test=0.61 on 1 df, p=0.434
n= 46, number of events= 12
============================
TCGA-COAD BECN1
[1] 291
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 17 3 3.19 0.0108 0.0161
strata=LOW 29 9 8.81 0.0039 0.0161
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.08831 1.09232 0.69600 0.127 0.899
Likelihood ratio test=0.02 on 1 df, p=0.8985
n= 46, number of events= 12
============================
TCGA-COAD FTMT
============================
TCGA-COAD HCAR1
[1] 292
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 36 8 8.15 0.00289 0.0114
strata=LOW 10 4 3.85 0.00612 0.0114
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.07288 1.07560 0.68359 0.107 0.915
Likelihood ratio test=0.01 on 1 df, p=0.9156
n= 46, number of events= 12
============================
TCGA-COAD HILPDA
[1] 293
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 30 8 8.67 0.0518 0.203
strata=LOW 16 4 3.33 0.1348 0.203
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2911 1.3380 0.6477 0.45 0.653
Likelihood ratio test=0.2 on 1 df, p=0.6567
n= 46, number of events= 12
============================
TCGA-COAD GSTM1
[1] 294
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
n=45, 1 observation deleted due to missingness.
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 27 6 7.38 0.258 0.711
strata=LOW 18 6 4.62 0.412 0.711
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5058 1.6583 0.6062 0.834 0.404
Likelihood ratio test=0.7 on 1 df, p=0.4029
n= 45, number of events= 12
(1 observation deleted due to missingness)
============================
TCGA-COAD MIR222
[1] 295
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
n=23, 23 observations deleted due to missingness.
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 21 2 2.584 0.132 0.965
strata=LOW 2 1 0.416 0.818 0.965
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.158 3.182 1.242 0.932 0.351
Likelihood ratio test=0.74 on 1 df, p=0.3887
n= 23, number of events= 3
(23 observations deleted due to missingness)
============================
TCGA-COAD RARRES2
[1] 296
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 23 6 7.04 0.154 0.417
strata=LOW 23 6 4.96 0.219 0.417
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3983 1.4893 0.6208 0.642 0.521
Likelihood ratio test=0.41 on 1 df, p=0.5195
n= 46, number of events= 12
============================
TCGA-COAD BRD4
[1] 297
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 7 2 1.24 0.4588 0.525
strata=LOW 39 10 10.76 0.0531 0.525
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5665 0.5675 0.7921 -0.715 0.474
Likelihood ratio test=0.46 on 1 df, p=0.4998
n= 46, number of events= 12
============================
TCGA-COAD SOCS1
[1] 298
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 1.99 0.512 0.658
strata=LOW 34 9 10.01 0.102 0.658
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5665 0.5675 0.7077 -0.8 0.423
Likelihood ratio test=0.6 on 1 df, p=0.4401
n= 46, number of events= 12
============================
TCGA-COAD MIR17
============================
TCGA-COAD GDF15
[1] 299
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 35 11 7.02 2.26 6.54
strata=LOW 11 1 4.98 3.19 6.54
Chisq= 6.5 on 1 degrees of freedom, p= 0.01
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.986e+01 2.372e-09 7.863e+03 -0.003 0.998
Likelihood ratio test=10.22 on 1 df, p=0.001387
n= 46, number of events= 12
============================
TCGA-COAD ARF6
[1] 300
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 17 3 3.71 0.136 0.218
strata=LOW 29 9 8.29 0.061 0.218
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3216 1.3794 0.6919 0.465 0.642
Likelihood ratio test=0.22 on 1 df, p=0.6355
n= 46, number of events= 12
============================
TCGA-COAD CDO1
[1] 301
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 32 8 8.93 0.096 0.412
strata=LOW 14 4 3.07 0.279 0.412
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4173 1.5178 0.6545 0.638 0.524
Likelihood ratio test=0.39 on 1 df, p=0.5303
n= 46, number of events= 12
============================
TCGA-COAD CAMKK2
[1] 302
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.2 0.0179 0.023
strata=LOW 35 10 9.8 0.0040 0.023
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1202 1.1278 0.7928 0.152 0.879
Likelihood ratio test=0.02 on 1 df, p=0.8781
n= 46, number of events= 12
============================
TCGA-COAD LINC01606
[1] 303
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
n=26, 20 observations deleted due to missingness.
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 23 6 6.448 0.0311 0.423
strata=LOW 3 1 0.552 0.3632 0.423
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7358 2.0872 1.1574 0.636 0.525
Likelihood ratio test=0.35 on 1 df, p=0.5517
n= 26, number of events= 7
(20 observations deleted due to missingness)
============================
TCGA-COAD BACH1
[1] 304
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 4 3.63 0.0381 0.0602
strata=LOW 31 8 8.37 0.0165 0.0602
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1587 0.8532 0.6478 -0.245 0.806
Likelihood ratio test=0.06 on 1 df, p=0.8075
n= 46, number of events= 12
============================
TCGA-COAD DPP4
[1] 305
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 25 7 6.57 0.0287 0.069
strata=LOW 21 5 5.43 0.0347 0.069
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1595 0.8526 0.6077 -0.262 0.793
Likelihood ratio test=0.07 on 1 df, p=0.7926
n= 46, number of events= 12
============================
TCGA-COAD PPP1R13L
[1] 306
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 13 4 3.08 0.275 0.507
strata=LOW 33 8 8.92 0.095 0.507
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4801 0.6187 0.6809 -0.705 0.481
Likelihood ratio test=0.46 on 1 df, p=0.4974
n= 46, number of events= 12
============================
TCGA-COAD MIR150
============================
TCGA-COAD FLT3
[1] 307
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 30 6 7.01 0.145 0.402
strata=LOW 16 6 4.99 0.204 0.402
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3824 1.4657 0.6069 0.63 0.529
Likelihood ratio test=0.39 on 1 df, p=0.5322
n= 46, number of events= 12
============================
TCGA-COAD MAP1LC3A
[1] 308
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 16 4 4.05 0.000734 0.00119
strata=LOW 30 8 7.95 0.000375 0.00119
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.02179 1.02203 0.63278 0.034 0.973
Likelihood ratio test=0 on 1 df, p=0.9725
n= 46, number of events= 12
============================
TCGA-COAD A2M-AS1
[1] 309
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 29 7 6.52 0.0357 0.0883
strata=LOW 17 5 5.48 0.0424 0.0883
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1867 0.8297 0.6291 -0.297 0.767
Likelihood ratio test=0.09 on 1 df, p=0.7649
n= 46, number of events= 12
============================
TCGA-COAD PDSS2
[1] 310
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 13 4 3.35 0.1240 0.188
strata=LOW 33 8 8.65 0.0481 0.188
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2804 0.7555 0.6484 -0.432 0.665
Likelihood ratio test=0.18 on 1 df, p=0.6688
n= 46, number of events= 12
============================
TCGA-COAD DNAJB6
[1] 311
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 7 0 0.969 0.9694 1.08
strata=LOW 39 12 11.031 0.0852 1.08
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.817e+01 7.812e+07 8.500e+03 0.002 0.998
Likelihood ratio test=2.05 on 1 df, p=0.1526
n= 46, number of events= 12
============================
TCGA-COAD SUV39H1
[1] 312
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 1 3.1 1.423 2.01
strata=LOW 35 11 8.9 0.496 2.01
Chisq= 2 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.379 3.971 1.052 1.311 0.19
Likelihood ratio test=2.48 on 1 df, p=0.1156
n= 46, number of events= 12
============================
TCGA-COAD LPCAT3
[1] 313
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 26 5 6.08 0.192 0.458
strata=LOW 20 7 5.92 0.197 0.458
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4180 1.5189 0.6216 0.672 0.501
Likelihood ratio test=0.45 on 1 df, p=0.501
n= 46, number of events= 12
============================
TCGA-COAD MIR761
============================
TCGA-COAD CDCA3
[1] 314
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 18 6 5.34 0.0825 0.174
strata=LOW 28 6 6.66 0.0661 0.174
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2569 0.7734 0.6170 -0.416 0.677
Likelihood ratio test=0.17 on 1 df, p=0.6787
n= 46, number of events= 12
============================
TCGA-COAD EPAS1
[1] 315
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 27 7 6.38 0.0599 0.154
strata=LOW 19 5 5.62 0.0680 0.154
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2566 0.7737 0.6545 -0.392 0.695
Likelihood ratio test=0.16 on 1 df, p=0.6919
n= 46, number of events= 12
============================
TCGA-COAD SLC11A2
[1] 316
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.82 0.2380 0.324
strata=LOW 35 10 9.18 0.0731 0.324
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4434 1.5580 0.7852 0.565 0.572
Likelihood ratio test=0.35 on 1 df, p=0.555
n= 46, number of events= 12
============================
TCGA-COAD CREB3
[1] 317
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.45 0.0836 0.112
strata=LOW 35 10 9.55 0.0215 0.112
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2649 1.3033 0.7941 0.334 0.739
Likelihood ratio test=0.12 on 1 df, p=0.7322
n= 46, number of events= 12
============================
TCGA-COAD ATF3
[1] 318
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 20 7 4.57 1.288 2.23
strata=LOW 26 5 7.43 0.793 2.23
Chisq= 2.2 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.9118 0.4018 0.6305 -1.446 0.148
Likelihood ratio test=2.2 on 1 df, p=0.1384
n= 46, number of events= 12
============================
TCGA-COAD TGFB1
[1] 319
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 14 3 3.75 0.152 0.233
strata=LOW 32 9 8.25 0.069 0.233
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3269 1.3867 0.6804 0.48 0.631
Likelihood ratio test=0.24 on 1 df, p=0.6231
n= 46, number of events= 12
============================
TCGA-COAD SMG9
[1] 320
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 8 2 2.15 0.01082 0.0139
strata=LOW 38 10 9.85 0.00237 0.0139
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.09344 1.09795 0.79317 0.118 0.906
Likelihood ratio test=0.01 on 1 df, p=0.9054
n= 46, number of events= 12
============================
TCGA-COAD NOX4
[1] 321
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 35 10 9.44 0.0333 0.164
strata=LOW 11 2 2.56 0.1227 0.164
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3182 0.7274 0.7898 -0.403 0.687
Likelihood ratio test=0.17 on 1 df, p=0.6774
n= 46, number of events= 12
============================
TCGA-COAD MIR27A
============================
TCGA-COAD FOXP1
[1] 322
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 17 3 3.67 0.1239 0.202
strata=LOW 29 9 8.33 0.0547 0.202
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3126 1.3669 0.6985 0.447 0.655
Likelihood ratio test=0.21 on 1 df, p=0.6487
n= 46, number of events= 12
============================
TCGA-COAD SNCA
[1] 323
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 29 7 8.17 0.167 0.595
strata=LOW 17 5 3.83 0.357 0.595
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4924 1.6362 0.6446 0.764 0.445
Likelihood ratio test=0.58 on 1 df, p=0.4463
n= 46, number of events= 12
============================
TCGA-COAD ENPP2
[1] 324
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 30 6 7.17 0.189 0.546
strata=LOW 16 6 4.83 0.281 0.546
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4453 1.5610 0.6073 0.733 0.463
Likelihood ratio test=0.53 on 1 df, p=0.4681
n= 46, number of events= 12
============================
TCGA-COAD BRD2
[1] 325
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 13 2 2.83 0.2447 0.346
strata=LOW 33 10 9.17 0.0756 0.346
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4629 1.5887 0.7942 0.583 0.56
Likelihood ratio test=0.37 on 1 df, p=0.5428
n= 46, number of events= 12
============================
TCGA-COAD ISCU
[1] 326
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.77 0.01978 0.0274
strata=LOW 35 9 9.23 0.00593 0.0274
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1144 0.8919 0.6913 -0.166 0.869
Likelihood ratio test=0.03 on 1 df, p=0.8695
n= 46, number of events= 12
============================
TCGA-COAD PHF21A
[1] 327
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.55 0.0790 0.108
strata=LOW 34 9 9.45 0.0213 0.108
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2277 0.7963 0.6956 -0.327 0.743
Likelihood ratio test=0.1 on 1 df, p=0.7472
n= 46, number of events= 12
============================
TCGA-COAD PARP6
[1] 328
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 8 2 2.5 0.0984 0.128
strata=LOW 38 10 9.5 0.0258 0.128
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2793 1.3223 0.7835 0.357 0.721
Likelihood ratio test=0.13 on 1 df, p=0.7137
n= 46, number of events= 12
============================
TCGA-COAD ZEB1
[1] 329
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 29 9 8.56 0.0226 0.0843
strata=LOW 17 3 3.44 0.0562 0.0843
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1989 0.8196 0.6861 -0.29 0.772
Likelihood ratio test=0.09 on 1 df, p=0.7689
n= 46, number of events= 12
============================
TCGA-COAD LIG3
[1] 330
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 10 2 2.25 0.02735 0.0358
strata=LOW 36 10 9.75 0.00631 0.0358
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1502 1.1621 0.7953 0.189 0.85
Likelihood ratio test=0.04 on 1 df, p=0.848
n= 46, number of events= 12
============================
TCGA-COAD PEDS1
[1] 331
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 8 1 1.89 0.422 0.515
strata=LOW 38 11 10.11 0.079 0.515
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7391 2.0941 1.0527 0.702 0.483
Likelihood ratio test=0.6 on 1 df, p=0.4381
n= 46, number of events= 12
============================
TCGA-COAD RPPH1
============================
TCGA-COAD GFRA1
[1] 332
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 36 11 9.68 0.181 1.02
strata=LOW 10 1 2.32 0.754 1.02
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.0266 0.3582 1.0615 -0.967 0.334
Likelihood ratio test=1.21 on 1 df, p=0.2711
n= 46, number of events= 12
============================
TCGA-COAD AQP8
[1] 333
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 45 12 11.745 0.00552 0.263
strata=LOW 1 0 0.255 0.25468 0.263
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.705e+01 3.926e-08 9.835e+03 -0.002 0.999
Likelihood ratio test=0.52 on 1 df, p=0.4717
n= 46, number of events= 12
============================
TCGA-COAD SIRT1
[1] 334
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 3 3.44 0.0561 0.0859
strata=LOW 31 9 8.56 0.0225 0.0859
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2023 1.2242 0.6915 0.293 0.77
Likelihood ratio test=0.09 on 1 df, p=0.767
n= 46, number of events= 12
============================
TCGA-COAD MIR15A
============================
TCGA-COAD AKR1C3
[1] 335
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 29 5 7.32 0.733 2.22
strata=LOW 17 7 4.68 1.146 2.22
Chisq= 2.2 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8822 2.4163 0.6103 1.446 0.148
Likelihood ratio test=2.08 on 1 df, p=0.1493
n= 46, number of events= 12
============================
TCGA-COAD DLD
[1] 336
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 17 4 3.71 0.0230 0.0368
strata=LOW 29 8 8.29 0.0103 0.0368
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1242 0.8832 0.6478 -0.192 0.848
Likelihood ratio test=0.04 on 1 df, p=0.8486
n= 46, number of events= 12
============================
TCGA-COAD USP11
[1] 337
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 10 2 2.97 0.315 0.433
strata=LOW 36 10 9.03 0.103 0.433
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5101 1.6655 0.7834 0.651 0.515
Likelihood ratio test=0.47 on 1 df, p=0.493
n= 46, number of events= 12
============================
TCGA-COAD SREBF2
[1] 338
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 13 4 3.66 0.0311 0.0495
strata=LOW 33 8 8.34 0.0137 0.0495
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1441 0.8658 0.6481 -0.222 0.824
Likelihood ratio test=0.05 on 1 df, p=0.825
n= 46, number of events= 12
============================
TCGA-COAD MIR190A
============================
TCGA-COAD IFNA8
============================
TCGA-COAD KDM6B
[1] 339
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 16 3 3.96 0.235 0.402
strata=LOW 30 9 8.04 0.116 0.402
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4398 1.5525 0.6990 0.629 0.529
Likelihood ratio test=0.42 on 1 df, p=0.5192
n= 46, number of events= 12
============================
TCGA-COAD ACOT1
[1] 340
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 19 5 4.08 0.208 0.356
strata=LOW 27 7 7.92 0.107 0.356
Chisq= 0.4 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3785 0.6849 0.6378 -0.593 0.553
Likelihood ratio test=0.35 on 1 df, p=0.554
n= 46, number of events= 12
============================
TCGA-COAD RELA
[1] 341
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 9 2 1.94 0.001648 0.00205
strata=LOW 37 10 10.06 0.000318 0.00205
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.03587 0.96477 0.79191 -0.045 0.964
Likelihood ratio test=0 on 1 df, p=0.964
n= 46, number of events= 12
============================
TCGA-COAD SLC39A7
[1] 342
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 3.19 0.0108 0.0161
strata=LOW 34 9 8.81 0.0039 0.0161
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.08831 1.09232 0.69600 0.127 0.899
Likelihood ratio test=0.02 on 1 df, p=0.8985
n= 46, number of events= 12
============================
TCGA-COAD POM121L12
============================
TCGA-COAD MIR101-1
============================
TCGA-COAD GABPB1-AS1
[1] 343
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 14 2 3.49 0.638 0.942
strata=LOW 32 10 8.51 0.262 0.942
Chisq= 0.9 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7435 2.1032 0.7837 0.949 0.343
Likelihood ratio test=1.04 on 1 df, p=0.3076
n= 46, number of events= 12
============================
TCGA-COAD EGFR
[1] 344
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 22 5 4.75 0.01307 0.0254
strata=LOW 24 7 7.25 0.00857 0.0254
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1016 0.9034 0.6384 -0.159 0.874
Likelihood ratio test=0.03 on 1 df, p=0.8735
n= 46, number of events= 12
============================
TCGA-COAD BRD7
[1] 345
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 13 3 3.28 0.0232 0.0346
strata=LOW 33 9 8.72 0.0087 0.0346
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1287 1.1374 0.6920 0.186 0.852
Likelihood ratio test=0.04 on 1 df, p=0.8512
n= 46, number of events= 12
============================
TCGA-COAD MIR1287
============================
TCGA-COAD MIR23A
============================
TCGA-COAD LCE2C
============================
TCGA-COAD ADAMTS13
[1] 346
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 4 3.63 0.0383 0.0579
strata=LOW 31 8 8.37 0.0166 0.0579
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1517 0.8592 0.6311 -0.24 0.81
Likelihood ratio test=0.06 on 1 df, p=0.8114
n= 46, number of events= 12
============================
TCGA-COAD SIRT3
[1] 347
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 4 3.91 0.00217 0.00343
strata=LOW 31 8 8.09 0.00105 0.00343
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.03701 0.96366 0.63219 -0.059 0.953
Likelihood ratio test=0 on 1 df, p=0.9534
n= 46, number of events= 12
============================
TCGA-COAD CIRBP
[1] 348
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 14 4 3.65 0.0345 0.0546
strata=LOW 32 8 8.35 0.0151 0.0546
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1510 0.8598 0.6471 -0.233 0.815
Likelihood ratio test=0.05 on 1 df, p=0.8165
n= 46, number of events= 12
============================
TCGA-COAD BRDT
[1] 349
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
n=23, 23 observations deleted due to missingness.
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 18 7 5.79 0.255 0.927
strata=LOW 5 1 2.21 0.666 0.927
Chisq= 0.9 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.9906 0.3714 1.0711 -0.925 0.355
Likelihood ratio test=1.08 on 1 df, p=0.2979
n= 23, number of events= 8
(23 observations deleted due to missingness)
============================
TCGA-COAD KIF4A
[1] 350
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 22 5 6.28 0.262 0.607
strata=LOW 24 7 5.72 0.288 0.607
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4865 1.6266 0.6303 0.772 0.44
Likelihood ratio test=0.62 on 1 df, p=0.4323
n= 46, number of events= 12
============================
TCGA-COAD CPEB1
[1] 351
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 38 12 10.08 0.368 2.46
strata=LOW 8 0 1.92 1.925 2.46
Chisq= 2.5 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.940e+01 3.766e-09 1.038e+04 -0.002 0.999
Likelihood ratio test=4.34 on 1 df, p=0.03718
n= 46, number of events= 12
============================
TCGA-COAD LINC01833
[1] 352
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
n=39, 7 observations deleted due to missingness.
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 31 10 7.86 0.583 2.83
strata=LOW 8 0 2.14 2.141 2.83
Chisq= 2.8 on 1 degrees of freedom, p= 0.09
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.946e+01 3.547e-09 9.962e+03 -0.002 0.998
Likelihood ratio test=4.91 on 1 df, p=0.02664
n= 39, number of events= 10
(7 observations deleted due to missingness)
============================
TCGA-COAD MAPKAP1
[1] 353
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 7 2 1.61 0.0966 0.115
strata=LOW 39 10 10.39 0.0149 0.115
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2683 0.7647 0.7921 -0.339 0.735
Likelihood ratio test=0.11 on 1 df, p=0.7416
n= 46, number of events= 12
============================
TCGA-COAD ATF4
[1] 354
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 7 3 1.8 0.806 0.988
strata=LOW 39 9 10.2 0.142 0.988
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6755 0.5089 0.6925 -0.975 0.329
Likelihood ratio test=0.86 on 1 df, p=0.3537
n= 46, number of events= 12
============================
TCGA-COAD SLC7A11
[1] 355
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 35 9 8.7 0.0106 0.0409
strata=LOW 11 3 3.3 0.0280 0.0409
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1381 0.8710 0.6836 -0.202 0.84
Likelihood ratio test=0.04 on 1 df, p=0.8383
n= 46, number of events= 12
============================
TCGA-COAD EMC2
[1] 356
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 9 2 1.99 6.23e-05 7.81e-05
strata=LOW 37 10 10.01 1.24e-05 7.81e-05
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.006999 0.993025 0.792041 -0.009 0.993
Likelihood ratio test=0 on 1 df, p=0.993
n= 46, number of events= 12
============================
TCGA-COAD WWTR1
[1] 357
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 24 8 6.33 0.442 1.05
strata=LOW 22 4 5.67 0.493 1.05
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6842 0.5045 0.6799 -1.006 0.314
Likelihood ratio test=1.1 on 1 df, p=0.2932
n= 46, number of events= 12
============================
TCGA-COAD HSPA5
[1] 358
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.76 0.2112 0.283
strata=LOW 35 10 9.24 0.0632 0.283
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4139 1.5128 0.7831 0.529 0.597
Likelihood ratio test=0.3 on 1 df, p=0.5814
n= 46, number of events= 12
============================
TCGA-COAD BEX1
[1] 359
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 39 10 10.14 0.00185 0.0127
strata=LOW 7 2 1.86 0.01007 0.0127
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.09056 1.09479 0.80296 0.113 0.91
Likelihood ratio test=0.01 on 1 df, p=0.9109
n= 46, number of events= 12
============================
TCGA-COAD PML
[1] 360
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 4 1 1.51 0.1696 0.201
strata=LOW 42 11 10.49 0.0243 0.201
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4711 1.6017 1.0588 0.445 0.656
Likelihood ratio test=0.22 on 1 df, p=0.6359
n= 46, number of events= 12
============================
TCGA-COAD MIR142
============================
TCGA-COAD AEBP2
[1] 361
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 10 2 2.45 0.0836 0.112
strata=LOW 36 10 9.55 0.0215 0.112
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2649 1.3033 0.7941 0.334 0.739
Likelihood ratio test=0.12 on 1 df, p=0.7322
n= 46, number of events= 12
============================
TCGA-COAD GPAT4
[1] 362
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 10 3 2.23 0.262 0.34
strata=LOW 36 9 9.77 0.060 0.34
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4019 0.6690 0.6936 -0.579 0.562
Likelihood ratio test=0.32 on 1 df, p=0.5733
n= 46, number of events= 12
============================
TCGA-COAD CA9
[1] 363
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 39 10 10.38 0.0139 0.105
strata=LOW 7 2 1.62 0.0888 0.105
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2546 1.2900 0.7870 0.324 0.746
Likelihood ratio test=0.1 on 1 df, p=0.7527
n= 46, number of events= 12
============================
TCGA-COAD STK11
[1] 364
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 8 1 2.2 0.653 0.842
strata=LOW 38 11 9.8 0.146 0.842
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.9346 2.5463 1.0557 0.885 0.376
Likelihood ratio test=1 on 1 df, p=0.317
n= 46, number of events= 12
============================
TCGA-COAD TBK1
[1] 365
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 13 3 2.85 0.00778 0.0111
strata=LOW 33 9 9.15 0.00242 0.0111
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.07343 0.92920 0.69723 -0.105 0.916
Likelihood ratio test=0.01 on 1 df, p=0.9165
n= 46, number of events= 12
============================
TCGA-COAD CDKN2A
[1] 366
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 30 10 8.21 0.392 1.3
strata=LOW 16 2 3.79 0.848 1.3
Chisq= 1.3 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8678 0.4199 0.7836 -1.107 0.268
Likelihood ratio test=1.45 on 1 df, p=0.2286
n= 46, number of events= 12
============================
TCGA-COAD DCAF7
[1] 367
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.47 0.0894 0.12
strata=LOW 34 10 9.53 0.0232 0.12
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2737 1.3148 0.7934 0.345 0.73
Likelihood ratio test=0.13 on 1 df, p=0.7233
n= 46, number of events= 12
============================
TCGA-COAD MTF1
[1] 368
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 19 4 4.17 0.00707 0.0123
strata=LOW 27 8 7.83 0.00377 0.0123
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.07181 1.07445 0.64876 0.111 0.912
Likelihood ratio test=0.01 on 1 df, p=0.9117
n= 46, number of events= 12
============================
TCGA-COAD MEG8
[1] 369
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
n=45, 1 observation deleted due to missingness.
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 26 9 8.05 0.112 0.356
strata=LOW 19 3 3.95 0.228 0.356
Chisq= 0.4 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.402 0.669 0.678 -0.593 0.553
Likelihood ratio test=0.37 on 1 df, p=0.5421
n= 45, number of events= 12
(1 observation deleted due to missingness)
============================
TCGA-COAD CLTRN
[1] 370
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 3 4.66 0.591 1.14
strata=LOW 31 9 7.34 0.375 1.14
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8161 2.2617 0.7849 1.04 0.298
Likelihood ratio test=1.27 on 1 df, p=0.2607
n= 46, number of events= 12
============================
TCGA-COAD PARP11
[1] 371
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 18 3 4.78 0.662 1.21
strata=LOW 28 9 7.22 0.438 1.21
Chisq= 1.2 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7354 2.0864 0.6839 1.075 0.282
Likelihood ratio test=1.26 on 1 df, p=0.2609
n= 46, number of events= 12
============================
TCGA-COAD GABARAPL2
[1] 372
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 4 3.65 0.0345 0.0546
strata=LOW 31 8 8.35 0.0151 0.0546
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1510 0.8598 0.6471 -0.233 0.815
Likelihood ratio test=0.05 on 1 df, p=0.8165
n= 46, number of events= 12
============================
TCGA-COAD CDKN1A
[1] 373
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 32 7 7.61 0.0495 0.17
strata=LOW 14 5 4.39 0.0859 0.17
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2657 1.3043 0.6452 0.412 0.681
Likelihood ratio test=0.17 on 1 df, p=0.6843
n= 46, number of events= 12
============================
TCGA-COAD NEDD4L
[1] 374
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 25 6 7 0.142 0.369
strata=LOW 21 6 5 0.198 0.369
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3693 1.4467 0.6108 0.605 0.545
Likelihood ratio test=0.37 on 1 df, p=0.5444
n= 46, number of events= 12
============================
TCGA-COAD AR
[1] 375
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 28 8 8.31 0.0117 0.0412
strata=LOW 18 4 3.69 0.0264 0.0412
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1298 1.1386 0.6398 0.203 0.839
Likelihood ratio test=0.04 on 1 df, p=0.8401
n= 46, number of events= 12
============================
TCGA-COAD MIR20A
============================
TCGA-COAD HMOX1
[1] 376
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 31 5 6.96 0.553 1.7
strata=LOW 15 7 5.04 0.765 1.7
Chisq= 1.7 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8058 2.2385 0.6315 1.276 0.202
Likelihood ratio test=1.61 on 1 df, p=0.2047
n= 46, number of events= 12
============================
TCGA-COAD ZFP36
[1] 377
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 24 6 5.72 0.0139 0.0304
strata=LOW 22 6 6.28 0.0126 0.0304
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1083 0.8974 0.6213 -0.174 0.862
Likelihood ratio test=0.03 on 1 df, p=0.8615
n= 46, number of events= 12
============================
TCGA-COAD MIR744
[1] 378
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
n=33, 13 observations deleted due to missingness.
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 23 6 7.32 0.238 0.936
strata=LOW 10 4 2.68 0.651 0.936
Chisq= 0.9 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6417 1.8998 0.6745 0.951 0.341
Likelihood ratio test=0.87 on 1 df, p=0.3508
n= 33, number of events= 10
(13 observations deleted due to missingness)
============================
TCGA-COAD CTSB
[1] 379
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 7 3 3.01 7.02e-05 0.00013
strata=LOW 39 9 8.99 2.35e-05 0.00013
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.00895 1.00899 0.78553 0.011 0.991
Likelihood ratio test=0 on 1 df, p=0.9909
n= 46, number of events= 12
============================
TCGA-COAD AGPS
[1] 380
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 14 4 3.55 0.0578 0.0901
strata=LOW 32 8 8.45 0.0243 0.0901
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1940 0.8236 0.6474 -0.3 0.764
Likelihood ratio test=0.09 on 1 df, p=0.766
n= 46, number of events= 12
============================
TCGA-COAD MT1DP
[1] 381
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 38 8 9.63 0.277 2.26
strata=LOW 8 4 2.37 1.130 2.26
Chisq= 2.3 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.9853 2.6785 0.6823 1.444 0.149
Likelihood ratio test=1.77 on 1 df, p=0.1836
n= 46, number of events= 12
============================
TCGA-COAD SNX4
[1] 382
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 16 4 3.44 0.0925 0.141
strata=LOW 30 8 8.56 0.0371 0.141
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2427 0.7845 0.6467 -0.375 0.707
Likelihood ratio test=0.14 on 1 df, p=0.71
n= 46, number of events= 12
============================
TCGA-COAD NR4A1
[1] 383
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 17 6 4.75 0.328 0.585
strata=LOW 29 6 7.25 0.215 0.585
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4625 0.6297 0.6097 -0.759 0.448
Likelihood ratio test=0.58 on 1 df, p=0.447
n= 46, number of events= 12
============================
TCGA-COAD MFN2
[1] 384
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 18 4 3.42 0.0983 0.153
strata=LOW 28 8 8.58 0.0392 0.153
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2553 0.7747 0.6544 -0.39 0.696
Likelihood ratio test=0.15 on 1 df, p=0.699
n= 46, number of events= 12
============================
TCGA-COAD SELENOI
[1] 385
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 18 3 3.57 0.0901 0.145
strata=LOW 28 9 8.43 0.0381 0.145
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2651 1.3036 0.6994 0.379 0.705
Likelihood ratio test=0.15 on 1 df, p=0.7003
n= 46, number of events= 12
============================
TCGA-COAD AGAP2-AS1
[1] 386
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 25 8 5.38 1.28 2.52
strata=LOW 21 4 6.62 1.04 2.52
Chisq= 2.5 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.0322 0.3562 0.6789 -1.521 0.128
Likelihood ratio test=2.61 on 1 df, p=0.1065
n= 46, number of events= 12
============================
TCGA-COAD TRIM46
[1] 387
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 5 2.5 2.485 3.48
strata=LOW 31 7 9.5 0.656 3.48
Chisq= 3.5 on 1 degrees of freedom, p= 0.06
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.1915 0.3038 0.6757 -1.763 0.0778
Likelihood ratio test=3.07 on 1 df, p=0.07966
n= 46, number of events= 12
============================
TCGA-COAD CYB5R1
[1] 388
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 13 4 3.01 0.325 0.467
strata=LOW 33 8 8.99 0.109 0.467
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4384 0.6451 0.6469 -0.678 0.498
Likelihood ratio test=0.44 on 1 df, p=0.5057
n= 46, number of events= 12
============================
TCGA-COAD PARK7
[1] 389
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 10 1 2.74 1.106 1.55
strata=LOW 36 11 9.26 0.327 1.55
Chisq= 1.6 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.238 3.449 1.058 1.17 0.242
Likelihood ratio test=1.88 on 1 df, p=0.1704
n= 46, number of events= 12
============================
TCGA-COAD CARS1
[1] 390
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 7 2 1.31 0.3647 0.423
strata=LOW 39 10 10.69 0.0447 0.423
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5115 0.5996 0.7951 -0.643 0.52
Likelihood ratio test=0.37 on 1 df, p=0.5413
n= 46, number of events= 12
============================
TCGA-COAD NOX1
[1] 391
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 22 4 3.65 0.0327 0.054
strata=LOW 24 8 8.35 0.0143 0.054
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1536 0.8576 0.6618 -0.232 0.816
Likelihood ratio test=0.05 on 1 df, p=0.8173
n= 46, number of events= 12
============================
TCGA-COAD VDR
[1] 392
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 26 7 5.67 0.314 0.753
strata=LOW 20 5 6.33 0.281 0.753
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6038 0.5467 0.7050 -0.856 0.392
Likelihood ratio test=0.78 on 1 df, p=0.3759
n= 46, number of events= 12
============================
TCGA-COAD PROK2
[1] 393
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 25 6 4.6 0.425 0.771
strata=LOW 21 6 7.4 0.265 0.771
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5424 0.5813 0.6242 -0.869 0.385
Likelihood ratio test=0.76 on 1 df, p=0.3833
n= 46, number of events= 12
============================
TCGA-COAD FABP4
[1] 394
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 41 11 10.74 0.0061 0.0608
strata=LOW 5 1 1.26 0.0522 0.0608
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2611 0.7702 1.0618 -0.246 0.806
Likelihood ratio test=0.06 on 1 df, p=0.7992
n= 46, number of events= 12
============================
TCGA-COAD ABCB10
[1] 395
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 14 3 3.23 0.01638 0.0243
strata=LOW 32 9 8.77 0.00603 0.0243
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1076 1.1136 0.6911 0.156 0.876
Likelihood ratio test=0.02 on 1 df, p=0.8754
n= 46, number of events= 12
============================
TCGA-COAD CP
[1] 396
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 39 10 9.67 0.0113 0.0598
strata=LOW 7 2 2.33 0.0468 0.0598
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1914 0.8258 0.7841 -0.244 0.807
Likelihood ratio test=0.06 on 1 df, p=0.8034
n= 46, number of events= 12
============================
TCGA-COAD MIR4735
============================
TCGA-COAD MIR130A
============================
TCGA-COAD TUG1
[1] 397
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 13 4 2.95 0.374 0.532
strata=LOW 33 8 9.05 0.122 0.532
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4672 0.6268 0.6464 -0.723 0.47
Likelihood ratio test=0.5 on 1 df, p=0.4784
n= 46, number of events= 12
============================
TCGA-COAD MIR9-3HG
[1] 398
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 30 7 7.69 0.0617 0.209
strata=LOW 16 5 4.31 0.1099 0.209
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2888 1.3348 0.6341 0.455 0.649
Likelihood ratio test=0.2 on 1 df, p=0.6532
n= 46, number of events= 12
============================
TCGA-COAD MIR196C
============================
TCGA-COAD IFNA21
[1] 399
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
n=17, 29 observations deleted due to missingness.
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 2 3.217 0.46 2.6
strata=LOW 2 2 0.783 1.89 2.6
Chisq= 2.6 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.766 5.849 1.235 1.43 0.153
Likelihood ratio test=2.2 on 1 df, p=0.1382
n= 17, number of events= 4
(29 observations deleted due to missingness)
============================
TCGA-COAD RP11-274B21.9
[1] 400
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
n=45, 1 observation deleted due to missingness.
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 24 7 5.82 0.239 0.519
strata=LOW 21 5 6.18 0.225 0.519
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4527 0.6359 0.6333 -0.715 0.475
Likelihood ratio test=0.53 on 1 df, p=0.4677
n= 45, number of events= 12
(1 observation deleted due to missingness)
============================
TCGA-COAD PVT1
[1] 401
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 32 8 7.76 0.00733 0.0254
strata=LOW 14 4 4.24 0.01343 0.0254
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1089 0.8969 0.6833 -0.159 0.873
Likelihood ratio test=0.03 on 1 df, p=0.8724
n= 46, number of events= 12
============================
TCGA-COAD MIR539
============================
TCGA-COAD IFNA2
============================
TCGA-COAD TFRC
[1] 402
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 6 4.35 0.629 1.19
strata=LOW 31 6 7.65 0.357 1.19
Chisq= 1.2 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6561 0.5189 0.6108 -1.074 0.283
Likelihood ratio test=1.11 on 1 df, p=0.2914
n= 46, number of events= 12
============================
TCGA-COAD ALOX15B
[1] 403
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 33 9 7.47 0.314 0.956
strata=LOW 13 3 4.53 0.517 0.956
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6850 0.5041 0.7113 -0.963 0.336
Likelihood ratio test=1.01 on 1 df, p=0.3146
n= 46, number of events= 12
============================
TCGA-COAD MPC1
[1] 404
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 27 6 6.62 0.0575 0.147
strata=LOW 19 6 5.38 0.0707 0.147
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2341 1.2637 0.6114 0.383 0.702
Likelihood ratio test=0.15 on 1 df, p=0.7031
n= 46, number of events= 12
============================
TCGA-COAD MTCH1
[1] 405
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 8 1 2.31 0.740 0.968
strata=LOW 38 11 9.69 0.176 0.968
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.9971 2.7105 1.0558 0.944 0.345
Likelihood ratio test=1.16 on 1 df, p=0.282
n= 46, number of events= 12
============================
TCGA-COAD MIR324
[1] 406
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
n=39, 7 observations deleted due to missingness.
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 25 7 5.7 0.294 0.749
strata=LOW 14 3 4.3 0.391 0.749
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6193 0.5383 0.7241 -0.855 0.392
Likelihood ratio test=0.78 on 1 df, p=0.3769
n= 39, number of events= 10
(7 observations deleted due to missingness)
============================
TCGA-COAD SNHG14
[1] 407
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 27 8 8.37 0.0162 0.0582
strata=LOW 19 4 3.63 0.0373 0.0582
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1547 1.1673 0.6420 0.241 0.81
Likelihood ratio test=0.06 on 1 df, p=0.8108
n= 46, number of events= 12
============================
TCGA-COAD PDK4
[1] 408
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 43 10 10.94 0.0809 0.943
strata=LOW 3 2 1.06 0.8354 0.943
Chisq= 0.9 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7539 2.1253 0.7941 0.949 0.342
Likelihood ratio test=0.77 on 1 df, p=0.38
n= 46, number of events= 12
============================
TCGA-COAD DUOX1
[1] 409
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 3 5.03 0.818 1.65
strata=LOW 31 9 6.97 0.590 1.65
Chisq= 1.6 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8929 2.4421 0.7133 1.252 0.211
Likelihood ratio test=1.74 on 1 df, p=0.1874
n= 46, number of events= 12
============================
TCGA-COAD LINC00886
[1] 410
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 24 9 7.35 0.371 1.03
strata=LOW 22 3 4.65 0.587 1.03
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6782 0.5075 0.6805 -0.997 0.319
Likelihood ratio test=1.08 on 1 df, p=0.2982
n= 46, number of events= 12
============================
TCGA-COAD NF2
[1] 411
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 8 2 1.94 0.001648 0.00205
strata=LOW 38 10 10.06 0.000318 0.00205
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.03587 0.96477 0.79191 -0.045 0.964
Likelihood ratio test=0 on 1 df, p=0.964
n= 46, number of events= 12
============================
TCGA-COAD MIR149
[1] 412
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
n=16, 30 observations deleted due to missingness.
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 5 4.768 0.0113 0.251
strata=LOW 1 0 0.232 0.2317 0.251
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.813e+01 1.339e-08 1.724e+04 -0.001 0.999
Likelihood ratio test=0.48 on 1 df, p=0.4874
n= 16, number of events= 5
(30 observations deleted due to missingness)
============================
TCGA-COAD CYP4F8
[1] 413
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
n=45, 1 observation deleted due to missingness.
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 28 6 5.21 0.121 0.257
strata=LOW 17 5 5.79 0.109 0.257
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3284 0.7201 0.6505 -0.505 0.614
Likelihood ratio test=0.26 on 1 df, p=0.6106
n= 45, number of events= 11
(1 observation deleted due to missingness)
============================
TCGA-COAD AKR1C1
[1] 414
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 31 8 7.54 0.0283 0.092
strata=LOW 15 4 4.46 0.0478 0.092
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2072 0.8129 0.6841 -0.303 0.762
Likelihood ratio test=0.09 on 1 df, p=0.7587
n= 46, number of events= 12
============================
TCGA-COAD PRKCA
[1] 415
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 19 6 3.88 1.158 1.91
strata=LOW 27 6 8.12 0.553 1.91
Chisq= 1.9 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8678 0.4199 0.6481 -1.339 0.181
Likelihood ratio test=1.84 on 1 df, p=0.1747
n= 46, number of events= 12
============================
TCGA-COAD CD44
[1] 416
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 21 6 6.11 0.00194 0.00439
strata=LOW 25 6 5.89 0.00201 0.00439
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.04042 1.04125 0.60993 0.066 0.947
Likelihood ratio test=0 on 1 df, p=0.9471
n= 46, number of events= 12
============================
TCGA-COAD FBXW7
[1] 417
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 15 3 3.06 0.00123 0.0018
strata=LOW 31 9 8.94 0.00042 0.0018
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.02952 1.02996 0.69617 0.042 0.966
Likelihood ratio test=0 on 1 df, p=0.9661
n= 46, number of events= 12
============================
TCGA-COAD YAP1
[1] 418
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 10 2 2.59 0.1330 0.175
strata=LOW 36 10 9.41 0.0365 0.175
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3259 1.3853 0.7833 0.416 0.677
Likelihood ratio test=0.19 on 1 df, p=0.667
n= 46, number of events= 12
============================
TCGA-COAD MTOR
[1] 419
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 16 3 3.59 0.0981 0.147
strata=LOW 30 9 8.41 0.0419 0.147
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2605 1.2976 0.6805 0.383 0.702
Likelihood ratio test=0.15 on 1 df, p=0.6966
n= 46, number of events= 12
============================
TCGA-COAD RICTOR
[1] 420
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 21 3 4.96 0.776 1.58
strata=LOW 25 9 7.04 0.547 1.58
Chisq= 1.6 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8524 2.3454 0.6968 1.223 0.221
Likelihood ratio test=1.63 on 1 df, p=0.2021
n= 46, number of events= 12
============================
TCGA-COAD WIPI2
[1] 421
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 9 1 2.1 0.574 0.731
strata=LOW 37 11 9.9 0.121 0.731
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8751 2.3992 1.0561 0.829 0.407
Likelihood ratio test=0.86 on 1 df, p=0.3527
n= 46, number of events= 12
============================
TCGA-COAD IREB2
[1] 422
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 14 3 3.48 0.0674 0.104
strata=LOW 32 9 8.52 0.0276 0.104
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2228 1.2496 0.6920 0.322 0.747
Likelihood ratio test=0.11 on 1 df, p=0.744
n= 46, number of events= 12
============================
TCGA-COAD GOT1
[1] 423
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 21 3 5.47 1.115 2.32
strata=LOW 25 9 6.53 0.934 2.32
Chisq= 2.3 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.0039 2.7290 0.6855 1.464 0.143
Likelihood ratio test=2.39 on 1 df, p=0.1219
n= 46, number of events= 12
============================
TCGA-COAD CD82
[1] 424
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.3 0.874 1.6
strata=LOW 35 7 8.7 0.332 1.6
Chisq= 1.6 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7812 0.4579 0.6321 -1.236 0.217
Likelihood ratio test=1.4 on 1 df, p=0.2368
n= 46, number of events= 12
============================
TCGA-COAD MAPK9
[1] 425
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 9 4 1.96 2.129 2.67
strata=LOW 37 8 10.04 0.415 2.67
Chisq= 2.7 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.0198 0.3607 0.6502 -1.568 0.117
Likelihood ratio test=2.23 on 1 df, p=0.1358
n= 46, number of events= 12
============================
TCGA-COAD LGMN
[1] 426
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 16 3 3.97 0.235 0.393
strata=LOW 30 9 8.03 0.116 0.393
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4311 1.5389 0.6927 0.622 0.534
Likelihood ratio test=0.41 on 1 df, p=0.5233
n= 46, number of events= 12
============================
TCGA-COAD PARP2
[1] 427
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 7 1 1.39 0.1084 0.127
strata=LOW 39 11 10.61 0.0142 0.127
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3739 1.4534 1.0566 0.354 0.723
Likelihood ratio test=0.14 on 1 df, p=0.7101
n= 46, number of events= 12
============================
TCGA-COAD MIR16-1
============================
TCGA-COAD ATG4D
[1] 428
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 19 3 5.51 1.145 2.41
strata=LOW 27 9 6.49 0.972 2.41
Chisq= 2.4 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.0237 2.7836 0.6867 1.491 0.136
Likelihood ratio test=2.48 on 1 df, p=0.1152
n= 46, number of events= 12
============================
TCGA-COAD RBMS1
[1] 429
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 18 5 4.29 0.1162 0.191
strata=LOW 28 7 7.71 0.0648 0.191
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.264 0.768 0.606 -0.436 0.663
Likelihood ratio test=0.19 on 1 df, p=0.6648
n= 46, number of events= 12
============================
TCGA-COAD GSTZ1
[1] 430
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 22 3 6.28 1.72 4.34
strata=LOW 24 9 5.72 1.89 4.34
Chisq= 4.3 on 1 degrees of freedom, p= 0.04
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.3458 3.8414 0.6905 1.949 0.0513
Likelihood ratio test=4.3 on 1 df, p=0.03818
n= 46, number of events= 12
============================
TCGA-COAD SRSF9
[1] 431
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 2 0 0.572 0.5719 0.612
strata=LOW 44 12 11.428 0.0286 0.612
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.811e+01 7.312e+07 1.093e+04 0.002 0.999
Likelihood ratio test=1.18 on 1 df, p=0.2768
n= 46, number of events= 12
============================
TCGA-COAD HIF1A
[1] 432
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 13 4 3.51 0.0689 0.103
strata=LOW 33 8 8.49 0.0285 0.103
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2021 0.8170 0.6316 -0.32 0.749
Likelihood ratio test=0.1 on 1 df, p=0.7513
n= 46, number of events= 12
============================
TCGA-COAD FNDC3B
[1] 433
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 19 5 4.16 0.1712 0.304
strata=LOW 27 7 7.84 0.0907 0.304
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3546 0.7014 0.6466 -0.548 0.583
Likelihood ratio test=0.3 on 1 df, p=0.5838
n= 46, number of events= 12
============================
TCGA-COAD RHEBP1
============================
TCGA-COAD PSEN1
[1] 434
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 17 4 3.96 0.000355 0.000592
strata=LOW 29 8 8.04 0.000175 0.000592
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.01577 0.98436 0.64810 -0.024 0.981
Likelihood ratio test=0 on 1 df, p=0.9806
n= 46, number of events= 12
============================
TCGA-COAD ADIPOQ
[1] 435
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 44 11 11.223 0.00442 0.0701
strata=LOW 2 1 0.777 0.06386 0.0701
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2805 1.3237 1.0624 0.264 0.792
Likelihood ratio test=0.06 on 1 df, p=0.799
n= 46, number of events= 12
============================
TCGA-COAD MUC1
[1] 436
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 31 6 7.58 0.328 1.11
strata=LOW 15 6 4.42 0.563 1.11
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6460 1.9079 0.6209 1.04 0.298
Likelihood ratio test=1.04 on 1 df, p=0.3068
n= 46, number of events= 12
============================
TCGA-COAD CAV1
[1] 437
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 28 8 8.18 0.00400 0.0136
strata=LOW 18 4 3.82 0.00856 0.0136
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.07421 1.07703 0.63760 0.116 0.907
Likelihood ratio test=0.01 on 1 df, p=0.9076
n= 46, number of events= 12
============================
TCGA-COAD SEC24B
[1] 438
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 2 2.88 0.2678 0.382
strata=LOW 34 10 9.12 0.0845 0.382
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4865 1.6265 0.7949 0.612 0.541
Likelihood ratio test=0.41 on 1 df, p=0.5221
n= 46, number of events= 12
============================
TCGA-COAD PRDX6
[1] 439
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 23 5 5.53 0.0505 0.107
strata=LOW 23 7 6.47 0.0432 0.107
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2031 1.2251 0.6210 0.327 0.744
Likelihood ratio test=0.11 on 1 df, p=0.7433
n= 46, number of events= 12
============================
TCGA-COAD TMEM161B-DT
[1] 440
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 17 4 4.22 0.01119 0.0196
strata=LOW 29 8 7.78 0.00606 0.0196
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.09071 1.09495 0.64888 0.14 0.889
Likelihood ratio test=0.02 on 1 df, p=0.8885
n= 46, number of events= 12
============================
TCGA-COAD PGD
[1] 441
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 6 2 1.3 0.3825 0.441
strata=LOW 40 10 10.7 0.0463 0.441
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5211 0.5939 0.7931 -0.657 0.511
Likelihood ratio test=0.39 on 1 df, p=0.5333
n= 46, number of events= 12
============================
TCGA-COAD RHOT1
[1] 442
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.29 0.2177 0.286
strata=LOW 35 9 9.71 0.0514 0.286
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3706 0.6903 0.6962 -0.532 0.595
Likelihood ratio test=0.27 on 1 df, p=0.6039
n= 46, number of events= 12
============================
TCGA-COAD ACSL1
[1] 443
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 14 3 3.36 0.0379 0.055
strata=LOW 32 9 8.64 0.0147 0.055
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1593 1.1727 0.6798 0.234 0.815
Likelihood ratio test=0.06 on 1 df, p=0.8126
n= 46, number of events= 12
============================
TCGA-COAD NEDD4
[1] 444
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 19 6 4.6 0.426 0.753
strata=LOW 27 6 7.4 0.265 0.753
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5286 0.5894 0.6158 -0.858 0.391
Likelihood ratio test=0.74 on 1 df, p=0.3891
n= 46, number of events= 12
============================
TCGA-COAD ELOVL5
[1] 445
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.61 0.715 1.15
strata=LOW 35 10 8.39 0.307 1.15
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8438 2.3252 0.8069 1.046 0.296
Likelihood ratio test=1.27 on 1 df, p=0.2599
n= 46, number of events= 12
============================
TCGA-COAD YY1AP1
[1] 446
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 12 3 2.3 0.216 0.283
strata=LOW 34 9 9.7 0.051 0.283
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3674 0.6926 0.6945 -0.529 0.597
Likelihood ratio test=0.27 on 1 df, p=0.6062
n= 46, number of events= 12
============================
Display the results only for genes where a significant difference in survival has been reported.
significant_genes[1] "NOX5" "CDH1" "LINC01134" "MYCN" "G6PD" "GDF15" "GSTZ1" num_significant_genes <- length(significant_genes)
if (num_significant_genes > 0) {
for (i in 1 : num_significant_genes) {
project <- significant_projects[[i]]
gene <- significant_genes[[i]]
cat(project, gene, "\n\n")
gene_df <- construct_gene_df(gene, project)
survival <- compute_survival_diff(gene_df)
cox <- compute_cox(gene_df)
print(survival)
cat("\n")
print(cox)
print(plot_survival(fit))
cat("\n\n============================\n\n")
}
}TCGA-COAD NOX5
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 26 3 6.23 1.67 3.94
strata=LOW 20 9 5.77 1.80 3.94
Chisq= 3.9 on 1 degrees of freedom, p= 0.05
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.2699 3.5606 0.6818 1.863 0.0625
Likelihood ratio test=3.96 on 1 df, p=0.04665
n= 46, number of events= 12
============================
TCGA-COAD CDH1
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 21 8 4.32 3.12 5.56
strata=LOW 25 4 7.68 1.76 5.56
Chisq= 5.6 on 1 degrees of freedom, p= 0.02
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.6773 0.1869 0.7946 -2.111 0.0348
Likelihood ratio test=5.74 on 1 df, p=0.01663
n= 46, number of events= 12
============================
TCGA-COAD LINC01134
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 18 7 3.8 2.69 4.47
strata=LOW 28 5 8.2 1.25 4.47
Chisq= 4.5 on 1 degrees of freedom, p= 0.03
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.3915 0.2487 0.7074 -1.967 0.0492
Likelihood ratio test=4.35 on 1 df, p=0.037
n= 46, number of events= 12
============================
TCGA-COAD MYCN
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 19 1 4.4 2.63 4.4
strata=LOW 27 11 7.6 1.52 4.4
Chisq= 4.4 on 1 degrees of freedom, p= 0.04
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.902 6.697 1.049 1.812 0.0699
Likelihood ratio test=5.37 on 1 df, p=0.02054
n= 46, number of events= 12
============================
TCGA-COAD G6PD
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 10 1 4.2 2.44 4.55
strata=LOW 36 11 7.8 1.31 4.55
Chisq= 4.6 on 1 degrees of freedom, p= 0.03
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.958e+01 3.191e+08 8.354e+03 0.002 0.998
Likelihood ratio test=7.6 on 1 df, p=0.005825
n= 46, number of events= 12
============================
TCGA-COAD GDF15
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 35 11 7.02 2.26 6.54
strata=LOW 11 1 4.98 3.19 6.54
Chisq= 6.5 on 1 degrees of freedom, p= 0.01
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.986e+01 2.372e-09 7.863e+03 -0.003 0.998
Likelihood ratio test=10.22 on 1 df, p=0.001387
n= 46, number of events= 12
============================
TCGA-COAD GSTZ1
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 22 3 6.28 1.72 4.34
strata=LOW 24 9 5.72 1.89 4.34
Chisq= 4.3 on 1 degrees of freedom, p= 0.04
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.3458 3.8414 0.6905 1.949 0.0513
Likelihood ratio test=4.3 on 1 df, p=0.03818
n= 46, number of events= 12
============================
De La Salle University, Manila, Philippines, gonzales.markedward@gmail.com↩︎
De La Salle University, Manila, Philippines, anish.shrestha@dlsu.edu.ph↩︎
---
title: "Survival Analysis"
subtitle: "Colorectal Cancer | Ferroptosis | Unique Genes per RCD Type | Log Fold Change"
author: 
  - Mark Edward M. Gonzales^[De La Salle University, Manila, Philippines, gonzales.markedward@gmail.com]
  - Dr. Anish M.S. Shrestha^[De La Salle University, Manila, Philippines, anish.shrestha@dlsu.edu.ph]
output: html_notebook
---

## I. Preliminaries

### Loading libraries

```{r, warning=FALSE, message=FALSE}
library("tidyverse")
library("tibble")
library("msigdbr")
library("ggplot2")
library("TCGAbiolinks")
library("RNAseqQC")
library("DESeq2")
library("ensembldb")
library("purrr")
library("magrittr")
library("vsn")
library("matrixStats")
library("dplyr")
library("grex")
library("survminer")
library("survival")
```

## II. Downloading the TCGA gene expression data 

Create a function for downloading TCGA gene expression data. 

For more detailed documentation, refer to `2. Differential Gene Expression Analysis - TCGA.Rmd`.

```{r}
query_and_filter_samples <- function(project) {
  query_tumor <- GDCquery(
    project = project,
    data.category = "Transcriptome Profiling",
    data.type = "Gene Expression Quantification",
    experimental.strategy = "RNA-Seq",
    workflow.type = "STAR - Counts",
    access = "open",
    sample.type = "Primary Tumor"
  )
  tumor <- getResults(query_tumor)

  query_normal <- GDCquery(
    project = project,
    data.category = "Transcriptome Profiling",
    data.type = "Gene Expression Quantification",
    experimental.strategy = "RNA-Seq",
    workflow.type = "STAR - Counts",
    access = "open",
    sample.type = "Solid Tissue Normal"
  )
  normal <- getResults(query_normal)

  submitter_ids <- inner_join(tumor, normal, by = "cases.submitter_id") %>%
    dplyr::select(cases.submitter_id)
  tumor <- tumor %>%
    dplyr::filter(cases.submitter_id %in% submitter_ids$cases.submitter_id)
  normal <- normal %>%
    dplyr::filter(cases.submitter_id %in% submitter_ids$cases.submitter_id)

  samples <- rbind(tumor, normal)
  unique(samples$sample_type)

  query_project <- GDCquery(
    project = project,
    data.category = "Transcriptome Profiling",
    data.type = "Gene Expression Quantification",
    experimental.strategy = "RNA-Seq",
    workflow.type = "STAR - Counts",
    access = "open",
    sample.type = c("Solid Tissue Normal", "Primary Tumor"),
    barcode = as.list(samples$sample.submitter_id)
  )

  # If this is your first time running this notebook (i.e., you have not yet downloaded the results of the query in the previous block),
  # uncomment the line below

  # GDCdownload(query_project)

  return(list(samples = samples, query_project = query_project))
}
```

Download the TCGA gene expression data for colorectal cancer (TCGA-COAD).

```{r, echo = TRUE, message = FALSE, results="hide"}
projects <- c("TCGA-COAD")

with_results_projects <- c()

samples <- list()
project_data <- list()

for (project in projects) {
  result <- tryCatch(
    {
      result <- query_and_filter_samples(project)
      samples[[project]] <- result$samples
      project_data[[project]] <- result$query_project

      with_results_projects <- c(with_results_projects, project)
    },
    error = function(e) {

    }
  )
}
```

Running the code block above should generate and populate a directory named `GDCdata`.

## III. Data preprocessing

Construct the RNA-seq count matrix for each cancer type.

```{r, echo = TRUE, message = FALSE, results="hide"}
tcga_data <- list()
tcga_matrix <- list()

projects <- with_results_projects
for (project in projects) {
  tcga_data[[project]] <- GDCprepare(project_data[[project]], summarizedExperiment = TRUE)
}
```

```{r}
for (project in projects) {
  count_matrix <- assay(tcga_data[[project]], "unstranded")

  # Remove duplicate entries
  count_matrix_df <- data.frame(count_matrix)
  count_matrix_df <- count_matrix_df[!duplicated(count_matrix_df), ]
  count_matrix <- data.matrix(count_matrix_df)
  rownames(count_matrix) <- cleanid(rownames(count_matrix))
  count_matrix <- count_matrix[!(duplicated(rownames(count_matrix)) | duplicated(rownames(count_matrix), fromLast = TRUE)), ]

  tcga_matrix[[project]] <- count_matrix
}
```
Format the `samples` table so that it can be fed as input to DESeq2.

```{r}
for (project in projects) {
  rownames(samples[[project]]) <- samples[[project]]$cases
  samples[[project]] <- samples[[project]] %>%
    dplyr::select(case = "cases.submitter_id", type = "sample_type")
  samples[[project]]$type <- str_replace(samples[[project]]$type, "Solid Tissue Normal", "normal")
  samples[[project]]$type <- str_replace(samples[[project]]$type, "Primary Tumor", "tumor")
}
```

DESeq2 requires the row names of `samples` should be identical to the column names of `count_matrix`.

```{r, echo = TRUE, results="hide"}
for (project in projects) {
  colnames(tcga_matrix[[project]]) <- gsub(x = colnames(tcga_matrix[[project]]), pattern = "\\.", replacement = "-")
  tcga_matrix[[project]] <- tcga_matrix[[project]][, rownames(samples[[project]])]

  # Sanity check
  print(all(colnames(tcga_matrix[[project]]) == rownames(samples[[project]])))
}
```

## IV. Differential gene expression analysis

For more detailed documentation on obtaining the gene set, refer to `7. Differential Gene Expression Analysis - TCGA - Pan-cancer - Unique Genes.Rmd`.

```{r}
RCDdb <- "temp/unique_genes/necroptosis_ferroptosis_pyroptosis/"
```

Write utility functions for filtering the gene sets, performing differential gene expression analysis, plotting the results, and performing variance-stabilizing transformation.

```{r}
filter_gene_set_and_perform_dgea <- function(genes) {
  tcga_rcd <- list()

  for (project in projects) {
    rownames(genes) <- genes$gene_id
    tcga_rcd[[project]] <- tcga_matrix[[project]][rownames(tcga_matrix[[project]]) %in% genes$gene_id, ]
    tcga_rcd[[project]] <- tcga_rcd[[project]][, rownames(samples[[project]])]
  }

  dds_rcd <- list()
  res_rcd <- list()

  for (project in projects) {
    print(project)
    print("=============")
    dds <- DESeqDataSetFromMatrix(
      countData = tcga_rcd[[project]],
      colData = samples[[project]],
      design = ~type
    )
    dds <- filter_genes(dds, min_count = 10)
    dds$type <- relevel(dds$type, ref = "normal")
    dds_rcd[[project]] <- DESeq(dds)
    res_rcd[[project]] <- results(dds_rcd[[project]])
  }

  deseq.bbl.data <- list()

  for (project in projects) {
    deseq.results <- res_rcd[[project]]
    deseq.bbl.data[[project]] <- data.frame(
      row.names = rownames(deseq.results),
      baseMean = deseq.results$baseMean,
      log2FoldChange = deseq.results$log2FoldChange,
      lfcSE = deseq.results$lfcSE,
      stat = deseq.results$stat,
      pvalue = deseq.results$pvalue,
      padj = deseq.results$padj,
      cancer_type = project,
      gene_symbol = genes[rownames(deseq.results), "gene"]
    )
  }

  deseq.bbl.data.combined <- bind_rows(deseq.bbl.data)
  deseq.bbl.data.combined <- dplyr::filter(deseq.bbl.data.combined, abs(log2FoldChange) >= 1.5 & padj < 0.05)

  return(deseq.bbl.data.combined)
}
```

```{r}
plot_dgea <- function(deseq.bbl.data.combined) {
  sizes <- c("<10^-15" = 4, "10^-10" = 3, "10^-5" = 2, "0.05" = 1)

  deseq.bbl.data.combined <- deseq.bbl.data.combined %>%
    mutate(fdr_category = cut(padj,
      breaks = c(-Inf, 1e-15, 1e-10, 1e-5, 0.05),
      labels = c("<10^-15", "10^-10", "10^-5", "0.05"),
      right = FALSE
    ))

  top_genes <- deseq.bbl.data.combined %>%
    group_by(cancer_type) %>%
    mutate(rank = rank(-abs(log2FoldChange))) %>%
    dplyr::filter(rank <= 10) %>%
    ungroup()

  ggplot(top_genes, aes(y = cancer_type, x = gene_symbol, size = fdr_category, fill = log2FoldChange)) +
    geom_point(alpha = 0.5, shape = 21, color = "black") +
    scale_size_manual(values = sizes) +
    scale_fill_gradient2(low = "blue", mid = "white", high = "red", limits = c(min(deseq.bbl.data.combined$log2FoldChange), max(deseq.bbl.data.combined$log2FoldChange))) +
    theme_minimal() +
    theme(
      axis.text.x = element_text(size = 9, angle = 90, hjust = 1)
    ) +
    theme(legend.position = "bottom") +
    theme(legend.position = "bottom") +
    labs(size = "Adjusted p-value", fill = "log2 FC", y = "Cancer type", x = "Gene")
}
```

```{r}
perform_vsd <- function(genes) {
  tcga_rcd <- list()

  for (project in projects) {
    rownames(genes) <- genes$gene_id
    tcga_rcd[[project]] <- tcga_matrix[[project]][rownames(tcga_matrix[[project]]) %in% genes$gene_id, ]
    tcga_rcd[[project]] <- tcga_rcd[[project]][, rownames(samples[[project]])]
  }

  vsd_rcd <- list()

  for (project in projects) {
    print(project)
    print("=============")
    dds <- DESeqDataSetFromMatrix(
      countData = tcga_rcd[[project]],
      colData = samples[[project]],
      design = ~type
    )
    dds <- filter_genes(dds, min_count = 10)

    # Perform variance stabilization
    dds <- estimateSizeFactors(dds)
    nsub <- sum(rowMeans(counts(dds, normalized = TRUE)) > 10)
    vsd <- vst(dds, nsub = nsub)
    vsd_rcd[[project]] <- assay(vsd)
  }

  return(vsd_rcd)
}
```


#### Ferroptosis

Fetch the gene set of interest.

```{r}
genes <- read.csv(paste0(RCDdb, "Ferroptosis.csv"))
print(genes)
genes$gene_id <- cleanid(genes$gene_id)
genes <- distinct(genes, gene_id, .keep_all = TRUE)
genes <- subset(genes, gene_id != "")
genes
```

Filter the genes to include only those in the gene set of interest, and then perform differential gene expression analysis.

```{r}
deseq.bbl.data.combined <- filter_gene_set_and_perform_dgea(genes)
deseq.bbl.data.combined
```

Plot the results.

```{r}
plot_dgea(deseq.bbl.data.combined)
```
Perform variance-stabilizing transformation for further downstream analysis (i.e., for survival analysis).

```{r, warning=FALSE}
vsd <- perform_vsd(genes)
```

## V. Downloading the clinical data

Download clinical data from TCGA, and perform some preprocessing:
- The `deceased` column should be `FALSE` if the patient is alive and `TRUE` otherwise
- The `overall_survival` column should reflect the follow-up time if the patient is alive and the days to death otherwise

```{r}
download_clinical_data <- function(project) {
  clinical_data <- GDCquery_clinic(project)
  clinical_data$deceased <- ifelse(clinical_data$vital_status == "Alive", FALSE, TRUE)
  clinical_data$overall_survival <- ifelse(clinical_data$vital_status == "Alive",
    clinical_data$days_to_last_follow_up,
    clinical_data$days_to_death
  )

  return(clinical_data)
}
```

```{r}
tcga_clinical <- list()
for (project in projects) {
  tcga_clinical[[project]] <- download_clinical_data(project)
}
```

## VI. Performing survival analysis

Write utility functions for performing survival analysis.


```{r}
construct_gene_df <- function(gene_of_interest, project) {
  normal_df <- tcga_matrix[[project]] %>%
    as.data.frame() %>%
    rownames_to_column(var = "gene_id") %>%
    gather(key = "case_id", value = "counts", -gene_id) %>%
    left_join(., genes, by = "gene_id") %>%
    dplyr::filter(gene == gene_of_interest) %>%
    dplyr::filter(case_id %in% rownames(samples[[project]] %>% dplyr::filter(type == "normal")))
  normal_df$case_id <- paste0(sapply(strsplit(as.character(normal_df$case_id), "-"), `[`, 1), '-',
                            sapply(strsplit(as.character(normal_df$case_id), "-"), `[`, 2), '-', 
                            sapply(strsplit(as.character(normal_df$case_id), "-"), `[`, 3))
  
  tumor_df <- tcga_matrix[[project]] %>%
      as.data.frame() %>%
      rownames_to_column(var = "gene_id") %>%
      gather(key = "case_id", value = "counts", -gene_id) %>%
      left_join(., genes, by = "gene_id") %>%
      dplyr::filter(gene == gene_of_interest) %>%
      dplyr::filter(case_id %in% rownames(samples[[project]] %>% dplyr::filter(type == "tumor")))
  tumor_df$case_id <- paste0(sapply(strsplit(as.character(tumor_df$case_id), "-"), `[`, 1), '-',
                            sapply(strsplit(as.character(tumor_df$case_id), "-"), `[`, 2), '-', 
                            sapply(strsplit(as.character(tumor_df$case_id), "-"), `[`, 3))
  
  gene_df <- inner_join(normal_df, tumor_df, by = c("gene_id", "case_id", "deathtype", "gene", "description", "gene_biotype", "pmid", "comment"))
  gene_df$log_fold = log2(gene_df$counts.y / gene_df$counts.x)
  
  gene_df$strata <- ifelse(abs(gene_df$log_fold) >= 1.5, "HIGH", "LOW")
  gene_df <- merge(gene_df, tcga_clinical[[project]], by.x = "case_id", by.y = "submitter_id")
  
  return(gene_df)
}
```

```{r}
compute_surival_fit <- function(gene_df) {
  return (survfit(Surv(overall_survival, deceased) ~ strata, data = gene_df))
}
```

```{r}
compute_cox <- function(gene_df) {
  return (coxph(Surv(overall_survival, deceased) ~ strata, data=gene_df))
}
```

```{r}
plot_survival <- function(fit) {
  return(ggsurvplot(fit,
    data = gene_df,
    pval = T,
    risk.table = T,
    risk.table.height = 0.3
  ))
}
```

```{r}
compute_survival_diff <- function(gene_df) {
  return(survdiff(Surv(overall_survival, deceased) ~ strata, data = gene_df))
}
```

Perform survival analysis by testing for the difference in the Kaplan-Meier curves using the G-rho family of Harrington and Fleming tests: https://rdrr.io/cran/survival/man/survdiff.html

Our genes of interest are the differentially expressed genes.

```{r}
significant_projects <- c()
significant_genes <- c()

ctr <- 1
for (project in projects) {
  for (gene in c(genes$gene)) {
    cat(project, gene, "\n\n")
    error <- tryCatch (
      {
        gene_df <- construct_gene_df(gene, project)
      },
      error = function(e) {
        cat("\n\n============================\n\n")
        e
      }
    )
    
    if(inherits(error, "error")) next

    if (nrow(gene_df) > 0) {
      fit <- compute_surival_fit(gene_df)
      tryCatch (
        {
          survival <- compute_survival_diff(gene_df)
          cox <- compute_cox(gene_df)
          print(ctr)
          ctr <- ctr + 1
          print(survival)
          cat("\n")
          print(cox)
          print(plot_survival(fit))
          if (pchisq(survival$chisq, length(survival$n)-1, lower.tail = FALSE) < 0.05) {
            significant_projects <- c(significant_projects, project)
            significant_genes <- c(significant_genes, gene)
          }
        },
        error = function(e) {
        }
      )
      
    }
    
    cat("\n\n============================\n\n")
  }
}
```

Display the results only for genes where a significant difference in survival has been reported.

```{r}
significant_genes
```

```{r}
num_significant_genes <- length(significant_genes)

if (num_significant_genes > 0) {
  for (i in 1 : num_significant_genes) {
    project <- significant_projects[[i]]
    gene <- significant_genes[[i]]
    
    cat(project, gene, "\n\n")
    gene_df <- construct_gene_df(gene, project)
    
    survival <- compute_survival_diff(gene_df)
    cox <- compute_cox(gene_df)
    print(survival)
    cat("\n")
    print(cox)
    print(plot_survival(fit))
    
    cat("\n\n============================\n\n")
  } 
}
```