Survival Analysis
Colorectal Cancer | Ferroptosis | Unique Genes per RCD Type | Gene Expression of Normal Samples
Mark Edward M. Gonzales1
Dr. Anish M.S. Shrestha2
I. Preliminaries
Loading libraries
library("tidyverse")
library("tibble")
library("msigdbr")
library("ggplot2")
library("TCGAbiolinks")
library("RNAseqQC")
library("DESeq2")
library("ensembldb")
library("purrr")
library("magrittr")
library("vsn")
library("matrixStats")
library("dplyr")
library("grex")
library("survminer")
library("survival")II. Downloading the TCGA gene expression data
Create a function for downloading TCGA gene expression data.
For more detailed documentation, refer to
2. Differential Gene Expression Analysis - TCGA.Rmd.
query_and_filter_samples <- function(project) {
query_tumor <- GDCquery(
project = project,
data.category = "Transcriptome Profiling",
data.type = "Gene Expression Quantification",
experimental.strategy = "RNA-Seq",
workflow.type = "STAR - Counts",
access = "open",
sample.type = "Primary Tumor"
)
tumor <- getResults(query_tumor)
query_normal <- GDCquery(
project = project,
data.category = "Transcriptome Profiling",
data.type = "Gene Expression Quantification",
experimental.strategy = "RNA-Seq",
workflow.type = "STAR - Counts",
access = "open",
sample.type = "Solid Tissue Normal"
)
normal <- getResults(query_normal)
submitter_ids <- inner_join(tumor, normal, by = "cases.submitter_id") %>%
dplyr::select(cases.submitter_id)
tumor <- tumor %>%
dplyr::filter(cases.submitter_id %in% submitter_ids$cases.submitter_id)
normal <- normal %>%
dplyr::filter(cases.submitter_id %in% submitter_ids$cases.submitter_id)
samples <- rbind(tumor, normal)
unique(samples$sample_type)
query_project <- GDCquery(
project = project,
data.category = "Transcriptome Profiling",
data.type = "Gene Expression Quantification",
experimental.strategy = "RNA-Seq",
workflow.type = "STAR - Counts",
access = "open",
sample.type = c("Solid Tissue Normal", "Primary Tumor"),
barcode = as.list(samples$sample.submitter_id)
)
# If this is your first time running this notebook (i.e., you have not yet downloaded the results of the query in the previous block),
# uncomment the line below
# GDCdownload(query_project)
return(list(samples = samples, query_project = query_project))
}Download the TCGA gene expression data for colorectal cancer (TCGA-COAD).
projects <- c("TCGA-COAD")
with_results_projects <- c()
samples <- list()
project_data <- list()
for (project in projects) {
result <- tryCatch(
{
result <- query_and_filter_samples(project)
samples[[project]] <- result$samples
project_data[[project]] <- result$query_project
with_results_projects <- c(with_results_projects, project)
},
error = function(e) {
}
)
}Running the code block above should generate and populate a directory
named GDCdata.
III. Data preprocessing
Construct the RNA-seq count matrix for each cancer type.
tcga_data <- list()
tcga_matrix <- list()
projects <- with_results_projects
for (project in projects) {
tcga_data[[project]] <- GDCprepare(project_data[[project]], summarizedExperiment = TRUE)
}for (project in projects) {
count_matrix <- assay(tcga_data[[project]], "unstranded")
# Remove duplicate entries
count_matrix_df <- data.frame(count_matrix)
count_matrix_df <- count_matrix_df[!duplicated(count_matrix_df), ]
count_matrix <- data.matrix(count_matrix_df)
rownames(count_matrix) <- cleanid(rownames(count_matrix))
count_matrix <- count_matrix[!(duplicated(rownames(count_matrix)) | duplicated(rownames(count_matrix), fromLast = TRUE)), ]
tcga_matrix[[project]] <- count_matrix
}Format the samples table so that it can be fed as input
to DESeq2.
for (project in projects) {
rownames(samples[[project]]) <- samples[[project]]$cases
samples[[project]] <- samples[[project]] %>%
dplyr::select(case = "cases.submitter_id", type = "sample_type")
samples[[project]]$type <- str_replace(samples[[project]]$type, "Solid Tissue Normal", "normal")
samples[[project]]$type <- str_replace(samples[[project]]$type, "Primary Tumor", "tumor")
}DESeq2 requires the row names of samples should be
identical to the column names of count_matrix.
for (project in projects) {
colnames(tcga_matrix[[project]]) <- gsub(x = colnames(tcga_matrix[[project]]), pattern = "\\.", replacement = "-")
tcga_matrix[[project]] <- tcga_matrix[[project]][, rownames(samples[[project]])]
# Sanity check
print(all(colnames(tcga_matrix[[project]]) == rownames(samples[[project]])))
}IV. Differential gene expression analysis
For more detailed documentation on obtaining the gene set, refer to
7. Differential Gene Expression Analysis - TCGA - Pan-cancer - Unique Genes.Rmd.
RCDdb <- "temp/unique_genes/necroptosis_ferroptosis_pyroptosis/"Write utility functions for filtering the gene sets, performing differential gene expression analysis, plotting the results, and performing variance-stabilizing transformation.
filter_gene_set_and_perform_dgea <- function(genes) {
tcga_rcd <- list()
for (project in projects) {
rownames(genes) <- genes$gene_id
tcga_rcd[[project]] <- tcga_matrix[[project]][rownames(tcga_matrix[[project]]) %in% genes$gene_id, ]
tcga_rcd[[project]] <- tcga_rcd[[project]][, rownames(samples[[project]])]
}
dds_rcd <- list()
res_rcd <- list()
for (project in projects) {
print(project)
print("=============")
dds <- DESeqDataSetFromMatrix(
countData = tcga_rcd[[project]],
colData = samples[[project]],
design = ~type
)
dds <- filter_genes(dds, min_count = 10)
dds$type <- relevel(dds$type, ref = "normal")
dds_rcd[[project]] <- DESeq(dds)
res_rcd[[project]] <- results(dds_rcd[[project]])
}
deseq.bbl.data <- list()
for (project in projects) {
deseq.results <- res_rcd[[project]]
deseq.bbl.data[[project]] <- data.frame(
row.names = rownames(deseq.results),
baseMean = deseq.results$baseMean,
log2FoldChange = deseq.results$log2FoldChange,
lfcSE = deseq.results$lfcSE,
stat = deseq.results$stat,
pvalue = deseq.results$pvalue,
padj = deseq.results$padj,
cancer_type = project,
gene_symbol = genes[rownames(deseq.results), "gene"]
)
}
deseq.bbl.data.combined <- bind_rows(deseq.bbl.data)
deseq.bbl.data.combined <- dplyr::filter(deseq.bbl.data.combined, abs(log2FoldChange) >= 1.5 & padj < 0.05)
return(deseq.bbl.data.combined)
}plot_dgea <- function(deseq.bbl.data.combined) {
sizes <- c("<10^-15" = 4, "10^-10" = 3, "10^-5" = 2, "0.05" = 1)
deseq.bbl.data.combined <- deseq.bbl.data.combined %>%
mutate(fdr_category = cut(padj,
breaks = c(-Inf, 1e-15, 1e-10, 1e-5, 0.05),
labels = c("<10^-15", "10^-10", "10^-5", "0.05"),
right = FALSE
))
top_genes <- deseq.bbl.data.combined %>%
group_by(cancer_type) %>%
mutate(rank = rank(-abs(log2FoldChange))) %>%
dplyr::filter(rank <= 10) %>%
ungroup()
ggplot(top_genes, aes(y = cancer_type, x = gene_symbol, size = fdr_category, fill = log2FoldChange)) +
geom_point(alpha = 0.5, shape = 21, color = "black") +
scale_size_manual(values = sizes) +
scale_fill_gradient2(low = "blue", mid = "white", high = "red", limits = c(min(deseq.bbl.data.combined$log2FoldChange), max(deseq.bbl.data.combined$log2FoldChange))) +
theme_minimal() +
theme(
axis.text.x = element_text(size = 9, angle = 90, hjust = 1)
) +
theme(legend.position = "bottom") +
theme(legend.position = "bottom") +
labs(size = "Adjusted p-value", fill = "log2 FC", y = "Cancer type", x = "Gene")
}perform_vsd <- function(genes) {
tcga_rcd <- list()
for (project in projects) {
rownames(genes) <- genes$gene_id
tcga_rcd[[project]] <- tcga_matrix[[project]][rownames(tcga_matrix[[project]]) %in% genes$gene_id, ]
tcga_rcd[[project]] <- tcga_rcd[[project]][, rownames(samples[[project]])]
}
vsd_rcd <- list()
for (project in projects) {
print(project)
print("=============")
dds <- DESeqDataSetFromMatrix(
countData = tcga_rcd[[project]],
colData = samples[[project]],
design = ~type
)
dds <- filter_genes(dds, min_count = 10)
# Perform variance stabilization
dds <- estimateSizeFactors(dds)
nsub <- sum(rowMeans(counts(dds, normalized = TRUE)) > 10)
vsd <- vst(dds, nsub = nsub)
vsd_rcd[[project]] <- assay(vsd)
}
return(vsd_rcd)
}Ferroptosis
Fetch the gene set of interest.
genes <- read.csv(paste0(RCDdb, "Ferroptosis.csv"))
print(genes)genes$gene_id <- cleanid(genes$gene_id)
genes <- distinct(genes, gene_id, .keep_all = TRUE)
genes <- subset(genes, gene_id != "")
genesFilter the genes to include only those in the gene set of interest, and then perform differential gene expression analysis.
deseq.bbl.data.combined <- filter_gene_set_and_perform_dgea(genes)[1] "TCGA-COAD"
[1] "============="Warning: some variables in design formula are characters, converting to factorsestimating size factors
estimating dispersions
gene-wise dispersion estimates
mean-dispersion relationship
final dispersion estimates
fitting model and testing
-- replacing outliers and refitting for 21 genes
-- DESeq argument 'minReplicatesForReplace' = 7
-- original counts are preserved in counts(dds)
estimating dispersions
fitting model and testingdeseq.bbl.data.combinedPlot the results.
plot_dgea(deseq.bbl.data.combined)
Perform variance-stabilizing transformation for further downstream analysis (i.e., for survival analysis).
vsd <- perform_vsd(genes)[1] "TCGA-COAD"
[1] "============="V. Downloading the clinical data
Download clinical data from TCGA, and perform some preprocessing: -
The deceased column should be FALSE if the
patient is alive and TRUE otherwise - The
overall_survival column should reflect the follow-up time
if the patient is alive and the days to death otherwise
download_clinical_data <- function(project) {
clinical_data <- GDCquery_clinic(project)
clinical_data$deceased <- ifelse(clinical_data$vital_status == "Alive", FALSE, TRUE)
clinical_data$overall_survival <- ifelse(clinical_data$vital_status == "Alive",
clinical_data$days_to_last_follow_up,
clinical_data$days_to_death
)
return(clinical_data)
}tcga_clinical <- list()
for (project in projects) {
tcga_clinical[[project]] <- download_clinical_data(project)
}VI. Performing survival analysis
Write utility functions for performing survival analysis.
construct_gene_df <- function(gene_of_interest, project) {
gene_df <- vsd[[project]] %>%
as.data.frame() %>%
rownames_to_column(var = "gene_id") %>%
gather(key = "case_id", value = "counts", -gene_id) %>%
left_join(., genes, by = "gene_id") %>%
dplyr::filter(gene == gene_of_interest) %>%
dplyr::filter(case_id %in% rownames(samples[[project]] %>% dplyr::filter(type == "normal")))
q1 <- quantile(gene_df$counts, probs = 0.25)
q3 <- quantile(gene_df$counts, probs = 0.75)
gene_df$strata <- ifelse(gene_df$counts >= q3, "HIGH", ifelse(gene_df$counts <= q1, "LOW", "MIDDLE"))
gene_df <- gene_df %>% dplyr::filter(strata %in% c("LOW", "HIGH"))
gene_df$case_id <- paste0(sapply(strsplit(as.character(gene_df$case_id), "-"), `[`, 1), '-',
sapply(strsplit(as.character(gene_df$case_id), "-"), `[`, 2), '-',
sapply(strsplit(as.character(gene_df$case_id), "-"), `[`, 3))
gene_df <- merge(gene_df, tcga_clinical[[project]], by.x = "case_id", by.y = "submitter_id")
return(gene_df)
}compute_surival_fit <- function(gene_df) {
return (survfit(Surv(overall_survival, deceased) ~ strata, data = gene_df))
}compute_cox <- function(gene_df) {
return (coxph(Surv(overall_survival, deceased) ~ strata, data=gene_df))
}plot_survival <- function(fit) {
return(ggsurvplot(fit,
data = gene_df,
pval = T,
risk.table = T,
risk.table.height = 0.3
))
}compute_survival_diff <- function(gene_df) {
return(survdiff(Surv(overall_survival, deceased) ~ strata, data = gene_df))
}Perform survival analysis by testing for the difference in the Kaplan-Meier curves using the G-rho family of Harrington and Fleming tests: https://rdrr.io/cran/survival/man/survdiff.html
Our genes of interest are the differentially expressed genes.
significant_projects <- c()
significant_genes <- c()
ctr <- 1
for (project in projects) {
for (gene in c(genes$gene)) {
cat(project, gene, "\n\n")
error <- tryCatch (
{
gene_df <- construct_gene_df(gene, project)
},
error = function(e) {
cat("\n\n============================\n\n")
e
}
)
if(inherits(error, "error")) next
if (nrow(gene_df) > 0) {
fit <- compute_surival_fit(gene_df)
tryCatch (
{
survival <- compute_survival_diff(gene_df)
cox <- compute_cox(gene_df)
print(ctr)
ctr <- ctr + 1
print(survival)
cat("\n")
print(cox)
print(plot_survival(fit))
if (pchisq(survival$chisq, length(survival$n)-1, lower.tail = FALSE) < 0.05) {
significant_projects <- c(significant_projects, project)
significant_genes <- c(significant_genes, gene)
}
},
error = function(e) {
}
)
}
cat("\n\n============================\n\n")
}
}TCGA-COAD MIR212
============================
TCGA-COAD NR5A2
[1] 1
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 4.32 0.404 1.07
strata=LOW 11 4 2.68 0.653 1.07
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7770 2.1750 0.7691 1.01 0.312
Likelihood ratio test=1.03 on 1 df, p=0.3094
n= 22, number of events= 7
============================
TCGA-COAD TFAM
[1] 2
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 4.3 0.0213 0.056
strata=LOW 11 4 3.7 0.0248 0.056
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1865 1.2050 0.7892 0.236 0.813
Likelihood ratio test=0.06 on 1 df, p=0.8124
n= 22, number of events= 8
============================
TCGA-COAD CREB5
[1] 3
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.56 0.587 1.72
strata=LOW 11 1 2.44 0.853 1.72
Chisq= 1.7 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.3714 0.2538 1.1262 -1.218 0.223
Likelihood ratio test=1.84 on 1 df, p=0.1749
n= 22, number of events= 6
============================
TCGA-COAD NOS2
[1] 4
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.92 0.00183 0.00363
strata=LOW 11 4 4.08 0.00175 0.00363
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.04291 0.95799 0.71240 -0.06 0.952
Likelihood ratio test=0 on 1 df, p=0.952
n= 22, number of events= 8
============================
TCGA-COAD HULC
[1] 5
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.07 0.420 0.786
strata=LOW 11 2 2.93 0.296 0.786
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8337 0.4345 0.9603 -0.868 0.385
Likelihood ratio test=0.77 on 1 df, p=0.3788
n= 22, number of events= 5
============================
TCGA-COAD PLXNB2
[1] 6
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.75 0.0228 0.051
strata=LOW 11 2 2.25 0.0279 0.051
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2065 0.8135 0.9157 -0.225 0.822
Likelihood ratio test=0.05 on 1 df, p=0.8206
n= 22, number of events= 5
============================
TCGA-COAD KIF20A
[1] 7
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 5.21 0.282 0.762
strata=LOW 11 5 3.79 0.388 0.762
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6400 1.8965 0.7447 0.859 0.39
Likelihood ratio test=0.77 on 1 df, p=0.3812
n= 22, number of events= 9
============================
TCGA-COAD TIMP1
[1] 8
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 4.81 0.295 0.957
strata=LOW 11 2 3.19 0.445 0.957
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8260 0.4378 0.8684 -0.951 0.341
Likelihood ratio test=0.97 on 1 df, p=0.3257
n= 22, number of events= 8
============================
TCGA-COAD MIR615
============================
TCGA-COAD MIR93
============================
TCGA-COAD ENO3
[1] 9
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 4.41 0.453 1.38
strata=LOW 11 4 2.59 0.772 1.38
Chisq= 1.4 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.9863 2.6814 0.8726 1.13 0.258
Likelihood ratio test=1.37 on 1 df, p=0.2415
n= 22, number of events= 7
============================
TCGA-COAD MMD
[1] 10
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.02 0.472 0.808
strata=LOW 11 2 2.98 0.321 0.808
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8089 0.4453 0.9229 -0.877 0.381
Likelihood ratio test=0.79 on 1 df, p=0.3743
n= 22, number of events= 5
============================
TCGA-COAD NQO1
[1] 11
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 4.35 0.420 0.929
strata=LOW 11 5 3.65 0.501 0.929
Chisq= 0.9 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6935 2.0007 0.7335 0.945 0.344
Likelihood ratio test=0.93 on 1 df, p=0.3352
n= 22, number of events= 8
============================
TCGA-COAD MARCHF5
[1] 12
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 4.08 0.00152 0.00313
strata=LOW 11 5 4.92 0.00126 0.00313
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.03985 1.04065 0.71181 0.056 0.955
Likelihood ratio test=0 on 1 df, p=0.9554
n= 22, number of events= 9
============================
TCGA-COAD JUN
[1] 13
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.88 0.201 0.586
strata=LOW 11 3 2.12 0.369 0.586
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6247 1.8677 0.8282 0.754 0.451
Likelihood ratio test=0.56 on 1 df, p=0.4541
n= 22, number of events= 6
============================
TCGA-COAD ALDH3A2
[1] 14
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 1 1.76 0.329 0.81
strata=LOW 11 2 1.24 0.468 0.81
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.061 2.890 1.233 0.861 0.389
Likelihood ratio test=0.8 on 1 df, p=0.3721
n= 22, number of events= 3
============================
TCGA-COAD ALOX5
[1] 15
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.37 1.121 1.81
strata=LOW 11 4 5.63 0.472 1.81
Chisq= 1.8 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.0324 0.3561 0.7945 -1.299 0.194
Likelihood ratio test=1.7 on 1 df, p=0.1918
n= 22, number of events= 8
============================
TCGA-COAD PARP9
[1] 16
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 4.23 0.0128 0.0371
strata=LOW 11 3 2.77 0.0196 0.0371
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1585 1.1717 0.8240 0.192 0.847
Likelihood ratio test=0.04 on 1 df, p=0.8476
n= 22, number of events= 7
============================
TCGA-COAD GLRX5
[1] 17
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 5.03 0.000173 0.000475
strata=LOW 11 4 3.97 0.000219 0.000475
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.01605 1.01618 0.73691 0.022 0.983
Likelihood ratio test=0 on 1 df, p=0.9826
n= 22, number of events= 9
============================
TCGA-COAD METTL14
[1] 18
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.29 0.894 1.57
strata=LOW 11 3 4.71 0.623 1.57
Chisq= 1.6 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.9048 0.4046 0.7455 -1.214 0.225
Likelihood ratio test=1.54 on 1 df, p=0.2146
n= 22, number of events= 8
============================
TCGA-COAD TOR2A
[1] 19
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.2 0.0120 0.0258
strata=LOW 11 4 3.8 0.0101 0.0258
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1315 1.1405 0.8189 0.161 0.872
Likelihood ratio test=0.03 on 1 df, p=0.8725
n= 22, number of events= 7
============================
TCGA-COAD PARP14
[1] 20
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.3 0.146 0.339
strata=LOW 11 2 2.7 0.180 0.339
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5071 0.6022 0.8797 -0.576 0.564
Likelihood ratio test=0.35 on 1 df, p=0.5559
n= 22, number of events= 6
============================
TCGA-COAD MIR130B
============================
TCGA-COAD CERS6-AS1
============================
TCGA-COAD NFS1
[1] 21
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.81 0.172 0.379
strata=LOW 11 5 4.19 0.156 0.379
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4668 1.5949 0.7656 0.61 0.542
Likelihood ratio test=0.38 on 1 df, p=0.5393
n= 22, number of events= 8
============================
TCGA-COAD SLC3A2
[1] 22
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 5.59 0.451 1.05
strata=LOW 11 6 4.41 0.570 1.05
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6603 1.9353 0.6540 1.01 0.313
Likelihood ratio test=1.04 on 1 df, p=0.3069
n= 22, number of events= 10
============================
TCGA-COAD ZFAS1
[1] 23
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.96 0.312 0.623
strata=LOW 11 5 4.04 0.229 0.623
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6746 1.9633 0.8706 0.775 0.438
Likelihood ratio test=0.64 on 1 df, p=0.4252
n= 22, number of events= 7
============================
TCGA-COAD PANX1
[1] 24
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 3.32 2.16 5.79
strata=LOW 11 0 2.68 2.68 5.79
Chisq= 5.8 on 1 degrees of freedom, p= 0.02
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.137e+01 5.262e-10 1.808e+04 -0.001 0.999
Likelihood ratio test=7.69 on 1 df, p=0.005547
n= 22, number of events= 6
============================
TCGA-COAD HSPB1
[1] 25
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.21 0.150 0.579
strata=LOW 11 1 1.79 0.351 0.579
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8424 0.4307 1.1375 -0.741 0.459
Likelihood ratio test=0.63 on 1 df, p=0.4271
n= 22, number of events= 6
============================
TCGA-COAD CREB1
[1] 26
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 4.06 0.000880 0.00209
strata=LOW 11 4 3.94 0.000907 0.00209
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.03507 1.03569 0.76685 0.046 0.964
Likelihood ratio test=0 on 1 df, p=0.9635
n= 22, number of events= 8
============================
TCGA-COAD EZH2
[1] 27
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.06 0.366 1.16
strata=LOW 11 3 1.94 0.577 1.16
Chisq= 1.2 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.197 3.310 1.172 1.021 0.307
Likelihood ratio test=1.21 on 1 df, p=0.2717
n= 22, number of events= 5
============================
TCGA-COAD SLC40A1
[1] 28
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 4.25 0.0146 0.0282
strata=LOW 11 6 5.75 0.0108 0.0282
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1134 1.1201 0.6760 0.168 0.867
Likelihood ratio test=0.03 on 1 df, p=0.8665
n= 22, number of events= 10
============================
TCGA-COAD PAQR3
[1] 29
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 1.84 0.0144 0.0268
strata=LOW 11 2 2.16 0.0122 0.0268
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1641 0.8487 1.0037 -0.163 0.87
Likelihood ratio test=0.03 on 1 df, p=0.8702
n= 22, number of events= 4
============================
TCGA-COAD MIR545
============================
TCGA-COAD MIR6077
============================
TCGA-COAD MIR424
============================
TCGA-COAD NOX5
[1] 30
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 1.4 0.262 0.492
strata=LOW 11 2 2.6 0.140 0.492
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8358 0.4335 1.2266 -0.681 0.496
Likelihood ratio test=0.5 on 1 df, p=0.4812
n= 22, number of events= 4
============================
TCGA-COAD DHODH
[1] 31
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.6 0.0454 0.219
strata=LOW 11 1 1.4 0.1163 0.219
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5666 0.5674 1.2262 -0.462 0.644
Likelihood ratio test=0.22 on 1 df, p=0.6355
n= 22, number of events= 5
============================
TCGA-COAD PTPN18
[1] 32
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.74 0.147 0.445
strata=LOW 11 3 2.26 0.244 0.445
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6005 1.8230 0.9134 0.657 0.511
Likelihood ratio test=0.44 on 1 df, p=0.5055
n= 22, number of events= 6
============================
TCGA-COAD IARS1
[1] 33
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.02 0.321 0.816
strata=LOW 11 2 2.98 0.324 0.816
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8096 0.4450 0.9196 -0.88 0.379
Likelihood ratio test=0.8 on 1 df, p=0.3723
n= 22, number of events= 6
============================
TCGA-COAD IL4R
[1] 34
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.6 0.0456 0.0992
strata=LOW 11 4 4.4 0.0372 0.0992
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2474 0.7808 0.7872 -0.314 0.753
Likelihood ratio test=0.1 on 1 df, p=0.7521
n= 22, number of events= 8
============================
TCGA-COAD SENP1
[1] 35
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.08 0.00230 0.00428
strata=LOW 11 4 3.92 0.00181 0.00428
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.0510 1.0523 0.7793 0.065 0.948
Likelihood ratio test=0 on 1 df, p=0.9478
n= 22, number of events= 7
============================
TCGA-COAD IFNA16
============================
TCGA-COAD SOX2
[1] 36
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.19 0.206 0.383
strata=LOW 11 3 3.81 0.172 0.383
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4714 0.6242 0.7689 -0.613 0.54
Likelihood ratio test=0.38 on 1 df, p=0.5371
n= 22, number of events= 7
============================
TCGA-COAD LIFR
[1] 37
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.17 0.319 0.571
strata=LOW 11 2 2.83 0.244 0.571
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6816 0.5058 0.9189 -0.742 0.458
Likelihood ratio test=0.56 on 1 df, p=0.4523
n= 22, number of events= 5
============================
TCGA-COAD MIR199A2
============================
TCGA-COAD COX4I2
[1] 38
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.77 0.0134 0.0417
strata=LOW 11 2 2.23 0.0228 0.0417
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1877 0.8288 0.9201 -0.204 0.838
Likelihood ratio test=0.04 on 1 df, p=0.8375
n= 22, number of events= 6
============================
TCGA-COAD ATF2
[1] 39
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.03 0.000395 0.000705
strata=LOW 11 4 3.97 0.000302 0.000705
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.02038 1.02059 0.76778 0.027 0.979
Likelihood ratio test=0 on 1 df, p=0.9788
n= 22, number of events= 7
============================
TCGA-COAD ABCC5
[1] 40
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.38 1.104 1.92
strata=LOW 11 2 3.62 0.725 1.92
Chisq= 1.9 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.1701 0.3103 0.8863 -1.32 0.187
Likelihood ratio test=1.87 on 1 df, p=0.171
n= 22, number of events= 6
============================
TCGA-COAD CCDC6
[1] 41
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 2.93 1.46 4.31
strata=LOW 11 0 2.07 2.07 4.31
Chisq= 4.3 on 1 degrees of freedom, p= 0.04
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.129e+01 5.675e-10 2.016e+04 -0.001 0.999
Likelihood ratio test=5.85 on 1 df, p=0.01555
n= 22, number of events= 5
============================
TCGA-COAD OTUB1
[1] 42
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 4.09 0.292 0.73
strata=LOW 11 5 3.91 0.306 0.73
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6567 1.9285 0.7813 0.841 0.401
Likelihood ratio test=0.72 on 1 df, p=0.3968
n= 22, number of events= 8
============================
TCGA-COAD ALOXE3
[1] 43
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 4.12 0.856 1.47
strata=LOW 15 5 6.88 0.513 1.47
Chisq= 1.5 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7686 0.4636 0.6487 -1.185 0.236
Likelihood ratio test=1.44 on 1 df, p=0.2298
n= 26, number of events= 11
============================
TCGA-COAD SCP2
[1] 44
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.7 0.131 0.285
strata=LOW 11 5 4.3 0.113 0.285
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4097 1.5064 0.7729 0.53 0.596
Likelihood ratio test=0.28 on 1 df, p=0.5938
n= 22, number of events= 8
============================
TCGA-COAD PHKG2
[1] 45
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.04 0.355 0.927
strata=LOW 11 4 2.96 0.365 0.927
Chisq= 0.9 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8657 2.3767 0.9254 0.936 0.35
Likelihood ratio test=0.9 on 1 df, p=0.3427
n= 22, number of events= 6
============================
TCGA-COAD MTDH
[1] 46
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 3.42 1.95 3.46
strata=LOW 11 4 6.58 1.01 3.46
Chisq= 3.5 on 1 degrees of freedom, p= 0.06
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.4108 0.2439 0.8208 -1.719 0.0857
Likelihood ratio test=3.49 on 1 df, p=0.06183
n= 22, number of events= 10
============================
TCGA-COAD ACO1
[1] 47
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 7 5.42 0.459 1.11
strata=LOW 11 3 4.58 0.544 1.11
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7294 0.4822 0.7078 -1.03 0.303
Likelihood ratio test=1.13 on 1 df, p=0.2881
n= 22, number of events= 10
============================
TCGA-COAD MIR137
============================
TCGA-COAD OIP5-AS1
[1] 48
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 5.56 0.435 1.26
strata=LOW 11 5 3.44 0.702 1.26
Chisq= 1.3 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8119 2.2522 0.7408 1.096 0.273
Likelihood ratio test=1.25 on 1 df, p=0.2631
n= 22, number of events= 9
============================
TCGA-COAD MIR494
============================
TCGA-COAD MLLT1
[1] 49
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 7 5.64 0.328 0.975
strata=LOW 11 2 3.36 0.550 0.975
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7939 0.4521 0.8241 -0.963 0.335
Likelihood ratio test=1.03 on 1 df, p=0.3091
n= 22, number of events= 9
============================
TCGA-COAD MIR19B1
============================
TCGA-COAD RPTOR
[1] 50
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 4.43 0.558 1.41
strata=LOW 11 2 3.57 0.692 1.41
Chisq= 1.4 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.9583 0.3835 0.8370 -1.145 0.252
Likelihood ratio test=1.46 on 1 df, p=0.2276
n= 22, number of events= 8
============================
TCGA-COAD GCH1
[1] 51
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 1.41 0.2458 0.465
strata=LOW 11 4 4.59 0.0756 0.465
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8134 0.4433 1.2259 -0.664 0.507
Likelihood ratio test=0.47 on 1 df, p=0.493
n= 22, number of events= 6
============================
TCGA-COAD PARP16
[1] 52
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.45 0.609 1.23
strata=LOW 11 5 3.55 0.592 1.23
Chisq= 1.2 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.9036 2.4685 0.8428 1.072 0.284
Likelihood ratio test=1.27 on 1 df, p=0.2603
n= 22, number of events= 7
============================
TCGA-COAD MIR9-3
============================
TCGA-COAD CISD3
[1] 53
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 5.11 0.00224 0.0064
strata=LOW 11 4 3.89 0.00293 0.0064
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.05949 1.06130 0.74349 0.08 0.936
Likelihood ratio test=0.01 on 1 df, p=0.9364
n= 22, number of events= 9
============================
TCGA-COAD USP35
[1] 54
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 6.06 0.000530 0.00163
strata=LOW 11 4 3.94 0.000814 0.00163
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.02869 1.02911 0.71173 0.04 0.968
Likelihood ratio test=0 on 1 df, p=0.9678
n= 22, number of events= 10
============================
TCGA-COAD PRKAA1
[1] 55
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.17 0.00888 0.0152
strata=LOW 11 5 4.83 0.00582 0.0152
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.09173 1.09606 0.74315 0.123 0.902
Likelihood ratio test=0.02 on 1 df, p=0.9014
n= 22, number of events= 8
============================
TCGA-COAD MAPK14
[1] 56
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.12 0.250 0.456
strata=LOW 11 6 6.88 0.113 0.456
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5133 0.5985 0.7685 -0.668 0.504
Likelihood ratio test=0.45 on 1 df, p=0.5013
n= 22, number of events= 10
============================
TCGA-COAD GRIA3
[1] 57
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.2 0.198 0.333
strata=LOW 11 5 5.8 0.109 0.333
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4079 0.6650 0.7113 -0.573 0.566
Likelihood ratio test=0.33 on 1 df, p=0.5676
n= 22, number of events= 9
============================
TCGA-COAD KDM5C
[1] 58
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.81 0.0135 0.0309
strata=LOW 11 3 3.19 0.0119 0.0309
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1607 0.8516 0.9149 -0.176 0.861
Likelihood ratio test=0.03 on 1 df, p=0.8599
n= 22, number of events= 6
============================
TCGA-COAD DECR1
[1] 59
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.1 0.0034 0.00718
strata=LOW 11 4 3.9 0.0027 0.00718
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.06987 1.07237 0.82492 0.085 0.932
Likelihood ratio test=0.01 on 1 df, p=0.9325
n= 22, number of events= 7
============================
TCGA-COAD VCP
[1] 60
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 1.96 2.13 3.51
strata=LOW 11 1 3.04 1.37 3.51
Chisq= 3.5 on 1 degrees of freedom, p= 0.06
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.8347 0.1597 1.1199 -1.638 0.101
Likelihood ratio test=3.51 on 1 df, p=0.06118
n= 22, number of events= 5
============================
TCGA-COAD MIR129-1
============================
TCGA-COAD PARP10
[1] 61
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.22 0.188 0.411
strata=LOW 11 3 3.78 0.160 0.411
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5517 0.5760 0.8710 -0.633 0.526
Likelihood ratio test=0.42 on 1 df, p=0.5163
n= 22, number of events= 7
============================
TCGA-COAD ULK2
[1] 62
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.66 0.679 1.88
strata=LOW 11 1 2.34 0.770 1.88
Chisq= 1.9 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.4600 0.2322 1.1593 -1.259 0.208
Likelihood ratio test=1.88 on 1 df, p=0.1705
n= 22, number of events= 5
============================
TCGA-COAD CISD1
[1] 63
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.18 0.209 0.45
strata=LOW 11 2 2.82 0.236 0.45
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5766 0.5618 0.8710 -0.662 0.508
Likelihood ratio test=0.46 on 1 df, p=0.4971
n= 22, number of events= 6
============================
TCGA-COAD MIR147A
============================
TCGA-COAD BBOX1-AS1
[1] 64
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 1 2.15 0.614 1.35
strata=LOW 11 4 2.85 0.463 1.35
Chisq= 1.3 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.264 3.538 1.160 1.089 0.276
Likelihood ratio test=1.39 on 1 df, p=0.2391
n= 22, number of events= 5
============================
TCGA-COAD RB1
[1] 65
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.92 0.00218 0.00375
strata=LOW 11 5 5.08 0.00125 0.00375
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.04684 0.95424 0.76475 -0.061 0.951
Likelihood ratio test=0 on 1 df, p=0.9512
n= 22, number of events= 8
============================
TCGA-COAD TTPA
[1] 66
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.71 0.0315 0.0578
strata=LOW 11 3 3.29 0.0259 0.0578
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1966 0.8215 0.8194 -0.24 0.81
Likelihood ratio test=0.06 on 1 df, p=0.8105
n= 22, number of events= 6
============================
TCGA-COAD CDC25A
[1] 67
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.14 0.181 0.381
strata=LOW 11 3 3.86 0.194 0.381
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4504 0.6373 0.7358 -0.612 0.54
Likelihood ratio test=0.39 on 1 df, p=0.5346
n= 22, number of events= 8
============================
TCGA-COAD PCAT1
[1] 68
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.47 0.951 1.69
strata=LOW 11 2 3.53 0.665 1.69
Chisq= 1.7 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.1043 0.3314 0.8871 -1.245 0.213
Likelihood ratio test=1.67 on 1 df, p=0.1967
n= 22, number of events= 6
============================
TCGA-COAD DAZAP1
[1] 69
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 5.76 0.101 0.307
strata=LOW 11 4 3.24 0.180 0.307
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3919 1.4798 0.7121 0.55 0.582
Likelihood ratio test=0.3 on 1 df, p=0.5832
n= 22, number of events= 9
============================
TCGA-COAD PEX2
[1] 70
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.86 0.256 0.49
strata=LOW 11 5 4.14 0.177 0.49
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5982 1.8189 0.8670 0.69 0.49
Likelihood ratio test=0.5 on 1 df, p=0.4786
n= 22, number of events= 7
============================
TCGA-COAD MIR124-3
============================
TCGA-COAD TRIM21
[1] 71
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.47 0.1159 0.229
strata=LOW 11 3 3.53 0.0808 0.229
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4342 0.6478 0.9140 -0.475 0.635
Likelihood ratio test=0.23 on 1 df, p=0.6311
n= 22, number of events= 6
============================
TCGA-COAD MEG3
[1] 72
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 5.01 0.197 0.464
strata=LOW 11 4 4.99 0.198 0.464
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4628 0.6295 0.6846 -0.676 0.499
Likelihood ratio test=0.46 on 1 df, p=0.4976
n= 22, number of events= 10
============================
TCGA-COAD GCLC
[1] 73
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 1 2.48 0.887 1.58
strata=LOW 11 6 4.52 0.488 1.58
Chisq= 1.6 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.302 3.675 1.106 1.177 0.239
Likelihood ratio test=1.76 on 1 df, p=0.1841
n= 22, number of events= 7
============================
TCGA-COAD IDH2
[1] 74
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 5.53 0.0404 0.13
strata=LOW 11 3 3.47 0.0644 0.13
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2760 0.7588 0.7691 -0.359 0.72
Likelihood ratio test=0.13 on 1 df, p=0.7184
n= 22, number of events= 9
============================
TCGA-COAD FNDC5
[1] 75
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.86 0.00422 0.0137
strata=LOW 11 3 3.14 0.00653 0.0137
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.09583 0.90862 0.81767 -0.117 0.907
Likelihood ratio test=0.01 on 1 df, p=0.9067
n= 22, number of events= 8
============================
TCGA-COAD FANCD2
[1] 76
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 4.23 0.359 1.67
strata=LOW 11 3 1.77 0.859 1.67
Chisq= 1.7 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.471 4.352 1.213 1.212 0.225
Likelihood ratio test=1.73 on 1 df, p=0.189
n= 22, number of events= 6
============================
TCGA-COAD LCN2
[1] 77
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 4.08 0.00147 0.00419
strata=LOW 11 3 2.92 0.00205 0.00419
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.05414 1.05564 0.83669 0.065 0.948
Likelihood ratio test=0 on 1 df, p=0.9484
n= 22, number of events= 7
============================
TCGA-COAD TFR2
[1] 78
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 4.41 0.452 1.4
strata=LOW 11 4 2.59 0.771 1.4
Chisq= 1.4 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.0053 2.7327 0.8822 1.14 0.254
Likelihood ratio test=1.4 on 1 df, p=0.2374
n= 22, number of events= 7
============================
TCGA-COAD PARP12
[1] 79
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.39 0.567 1.33
strata=LOW 11 5 3.61 0.532 1.33
Chisq= 1.3 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.9704 2.6389 0.8737 1.111 0.267
Likelihood ratio test=1.32 on 1 df, p=0.2501
n= 22, number of events= 7
============================
TCGA-COAD NR1D1
[1] 80
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.63 0.0378 0.111
strata=LOW 11 2 2.37 0.0579 0.111
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3036 0.7381 0.9155 -0.332 0.74
Likelihood ratio test=0.11 on 1 df, p=0.7381
n= 22, number of events= 6
============================
TCGA-COAD ATG13
[1] 81
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 4.09 0.289 0.711
strata=LOW 11 5 3.91 0.302 0.711
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6407 1.8978 0.7723 0.83 0.407
Likelihood ratio test=0.7 on 1 df, p=0.4036
n= 22, number of events= 8
============================
TCGA-COAD TMSB4X
[1] 82
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.04 0.357 0.726
strata=LOW 11 5 3.96 0.275 0.726
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7229 2.0603 0.8668 0.834 0.404
Likelihood ratio test=0.74 on 1 df, p=0.39
n= 22, number of events= 7
============================
TCGA-COAD CDK14
[1] 83
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.07 0.281 0.649
strata=LOW 11 3 3.93 0.220 0.649
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6542 0.5199 0.8256 -0.792 0.428
Likelihood ratio test=0.62 on 1 df, p=0.4319
n= 22, number of events= 7
============================
TCGA-COAD RP1-228H13.5
[1] 84
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 7 5.85 0.224 0.66
strata=LOW 11 3 4.15 0.317 0.66
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5859 0.5566 0.7314 -0.801 0.423
Likelihood ratio test=0.66 on 1 df, p=0.4149
n= 22, number of events= 10
============================
TCGA-COAD NOX3
============================
TCGA-COAD IFNA17
============================
TCGA-COAD ALOX12B
[1] 85
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 4.04 0.000374 0.00102
strata=LOW 11 3 2.96 0.000511 0.00102
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.02621 1.02656 0.82100 0.032 0.975
Likelihood ratio test=0 on 1 df, p=0.9745
n= 22, number of events= 7
============================
TCGA-COAD PGRMC1
[1] 86
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.61 0.057 0.125
strata=LOW 11 4 4.39 0.034 0.125
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3287 0.7198 0.9338 -0.352 0.725
Likelihood ratio test=0.13 on 1 df, p=0.7225
n= 22, number of events= 7
============================
TCGA-COAD ULK1
[1] 87
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.63 0.513 0.955
strata=LOW 11 3 4.37 0.427 0.955
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7047 0.4942 0.7357 -0.958 0.338
Likelihood ratio test=0.95 on 1 df, p=0.3288
n= 22, number of events= 8
============================
TCGA-COAD TRIM26
[1] 88
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.82 0.0121 0.0278
strata=LOW 11 2 2.18 0.0156 0.0278
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1526 0.8585 0.9156 -0.167 0.868
Likelihood ratio test=0.03 on 1 df, p=0.8671
n= 22, number of events= 5
============================
TCGA-COAD QSOX1
[1] 89
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.52 0.0759 0.297
strata=LOW 11 2 1.48 0.1800 0.297
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5493 1.7321 1.0198 0.539 0.59
Likelihood ratio test=0.29 on 1 df, p=0.5922
n= 22, number of events= 5
============================
TCGA-COAD ATM
[1] 90
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.24 0.0180 0.0423
strata=LOW 11 4 3.76 0.0156 0.0423
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1791 1.1962 0.8725 0.205 0.837
Likelihood ratio test=0.04 on 1 df, p=0.8358
n= 22, number of events= 7
============================
TCGA-COAD MIB2
[1] 91
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.74 0.0148 0.0369
strata=LOW 11 3 3.26 0.0214 0.0369
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1415 0.8680 0.7373 -0.192 0.848
Likelihood ratio test=0.04 on 1 df, p=0.847
n= 22, number of events= 8
============================
TCGA-COAD SLC1A5
[1] 92
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.7 0.0249 0.0743
strata=LOW 11 2 2.3 0.0399 0.0743
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2485 0.7800 0.9142 -0.272 0.786
Likelihood ratio test=0.07 on 1 df, p=0.7843
n= 22, number of events= 6
============================
TCGA-COAD MIR2115
============================
TCGA-COAD LINC00336
[1] 93
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.04 0.303 0.622
strata=LOW 11 3 3.96 0.232 0.622
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6746 0.5094 0.8712 -0.774 0.439
Likelihood ratio test=0.63 on 1 df, p=0.4257
n= 22, number of events= 7
============================
TCGA-COAD NDRG1
[1] 94
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.44 0.0564 0.133
strata=LOW 11 4 3.56 0.0545 0.133
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2973 1.3462 0.8185 0.363 0.716
Likelihood ratio test=0.13 on 1 df, p=0.7169
n= 22, number of events= 7
============================
TCGA-COAD TAFAZZIN
[1] 95
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.17 0.00937 0.03
strata=LOW 11 2 1.83 0.01626 0.03
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1734 1.1893 1.0015 0.173 0.863
Likelihood ratio test=0.03 on 1 df, p=0.8627
n= 22, number of events= 5
============================
TCGA-COAD MIR135B
============================
TCGA-COAD GLS2
[1] 96
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.33 0.104 0.258
strata=LOW 11 3 3.67 0.122 0.258
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3872 0.6789 0.7663 -0.505 0.613
Likelihood ratio test=0.26 on 1 df, p=0.6112
n= 22, number of events= 8
============================
TCGA-COAD HELLS
[1] 97
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 5.33 0.0846 0.235
strata=LOW 11 3 3.67 0.1228 0.235
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3574 0.6995 0.7411 -0.482 0.63
Likelihood ratio test=0.24 on 1 df, p=0.6258
n= 22, number of events= 9
============================
TCGA-COAD KLF2
[1] 98
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.03 0.235 0.559
strata=LOW 11 2 2.97 0.318 0.559
Chisq= 0.6 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6180 0.5390 0.8398 -0.736 0.462
Likelihood ratio test=0.58 on 1 df, p=0.445
n= 22, number of events= 7
============================
TCGA-COAD TFAP2A
[1] 99
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.05 1.86 3.22
strata=LOW 11 1 2.95 1.29 3.22
Chisq= 3.2 on 1 degrees of freedom, p= 0.07
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.7857 0.1677 1.1257 -1.586 0.113
Likelihood ratio test=3.26 on 1 df, p=0.07108
n= 22, number of events= 5
============================
TCGA-COAD FURIN
[1] 100
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.06 0.220 0.527
strata=LOW 11 3 3.94 0.226 0.527
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6007 0.5484 0.8398 -0.715 0.474
Likelihood ratio test=0.55 on 1 df, p=0.4581
n= 22, number of events= 8
============================
TCGA-COAD CDH1
[1] 101
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.84 0.00653 0.0149
strata=LOW 11 3 3.16 0.00795 0.0149
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.09426 0.91004 0.77362 -0.122 0.903
Likelihood ratio test=0.01 on 1 df, p=0.9028
n= 22, number of events= 7
============================
TCGA-COAD MIR6852
============================
TCGA-COAD MIR670
============================
TCGA-COAD TYRO3
[1] 102
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.62 0.528 2.57
strata=LOW 11 0 1.38 1.382 2.57
Chisq= 2.6 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.106e+01 7.122e-10 2.334e+04 -0.001 0.999
Likelihood ratio test=3.71 on 1 df, p=0.054
n= 22, number of events= 5
============================
TCGA-COAD MIR4715
============================
TCGA-COAD ABHD12
[1] 103
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 4.88 0.725 1.9
strata=LOW 11 7 5.12 0.692 1.9
Chisq= 1.9 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.9773 2.6574 0.7368 1.326 0.185
Likelihood ratio test=1.83 on 1 df, p=0.1755
n= 22, number of events= 10
============================
TCGA-COAD ATG7
[1] 104
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 4.17 0.00657 0.0141
strata=LOW 11 5 4.83 0.00566 0.0141
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.08487 1.08857 0.71592 0.119 0.906
Likelihood ratio test=0.01 on 1 df, p=0.9057
n= 22, number of events= 9
============================
TCGA-COAD MT1G
[1] 105
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 4.4 0.448 1.01
strata=LOW 11 6 4.6 0.429 1.01
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7200 2.0545 0.7334 0.982 0.326
Likelihood ratio test=1 on 1 df, p=0.3168
n= 22, number of events= 9
============================
TCGA-COAD SAT1
[1] 106
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 1 2.69 1.059 2.32
strata=LOW 11 5 3.31 0.859 2.32
Chisq= 2.3 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.554 4.729 1.123 1.384 0.166
Likelihood ratio test=2.43 on 1 df, p=0.1187
n= 22, number of events= 6
============================
TCGA-COAD MIR182
============================
TCGA-COAD HOTAIR
[1] 107
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.34 1.173 1.6
strata=LOW 23 6 7.66 0.359 1.6
Chisq= 1.6 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8323 0.4350 0.6759 -1.231 0.218
Likelihood ratio test=1.44 on 1 df, p=0.2309
n= 34, number of events= 10
============================
TCGA-COAD PIR
[1] 108
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.29 0.222 0.416
strata=LOW 11 2 2.71 0.187 0.416
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5859 0.5566 0.9212 -0.636 0.525
Likelihood ratio test=0.41 on 1 df, p=0.5195
n= 22, number of events= 5
============================
TCGA-COAD ELAVL1
[1] 109
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.34 0.102 0.299
strata=LOW 11 2 2.66 0.166 0.299
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4699 0.6251 0.8670 -0.542 0.588
Likelihood ratio test=0.31 on 1 df, p=0.5795
n= 22, number of events= 7
============================
TCGA-COAD ACADSB
[1] 110
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 1 2.11 0.582 1.26
strata=LOW 11 3 1.89 0.647 1.26
Chisq= 1.3 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.240 3.454 1.169 1.06 0.289
Likelihood ratio test=1.31 on 1 df, p=0.2527
n= 22, number of events= 4
============================
TCGA-COAD NCOA4
[1] 111
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.84 0.247 0.48
strata=LOW 11 5 4.16 0.168 0.48
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5978 1.8181 0.8749 0.683 0.494
Likelihood ratio test=0.49 on 1 df, p=0.4834
n= 22, number of events= 7
============================
TCGA-COAD IFNA10
============================
TCGA-COAD IFNA13
============================
TCGA-COAD MIR9-2
============================
TCGA-COAD RRM2
[1] 112
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.87 0.00451 0.012
strata=LOW 11 3 3.13 0.00557 0.012
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.09087 0.91313 0.82895 -0.11 0.913
Likelihood ratio test=0.01 on 1 df, p=0.9127
n= 22, number of events= 7
============================
TCGA-COAD EPSTI1
[1] 113
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.79 0.0115 0.0255
strata=LOW 11 4 4.21 0.0103 0.0255
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1232 0.8841 0.7717 -0.16 0.873
Likelihood ratio test=0.03 on 1 df, p=0.8728
n= 22, number of events= 8
============================
TCGA-COAD LINC00551
[1] 114
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 3.36 2.08 4.03
strata=LOW 11 1 3.64 1.92 4.03
Chisq= 4 on 1 degrees of freedom, p= 0.04
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.8886 0.1513 1.0832 -1.743 0.0812
Likelihood ratio test=4.42 on 1 df, p=0.03555
n= 22, number of events= 7
============================
TCGA-COAD SLC25A28
[1] 115
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.81 0.373 0.962
strata=LOW 11 2 3.19 0.445 0.962
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8301 0.4360 0.8700 -0.954 0.34
Likelihood ratio test=0.97 on 1 df, p=0.3243
n= 22, number of events= 7
============================
TCGA-COAD LINC00973
============================
TCGA-COAD MIR378A
============================
TCGA-COAD MGST1
[1] 116
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.55 0.591 1.21
strata=LOW 11 3 4.45 0.472 1.21
Chisq= 1.2 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8958 0.4083 0.8405 -1.066 0.287
Likelihood ratio test=1.25 on 1 df, p=0.2627
n= 22, number of events= 8
============================
TCGA-COAD MIB1
[1] 117
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 2.73 1.88 5.25
strata=LOW 11 0 2.27 2.27 5.25
Chisq= 5.2 on 1 degrees of freedom, p= 0.02
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.151e+01 4.555e-10 2.043e+04 -0.001 0.999
Likelihood ratio test=6.7 on 1 df, p=0.009615
n= 22, number of events= 5
============================
TCGA-COAD SRC
[1] 118
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.36 0.0380 0.088
strata=LOW 11 3 2.64 0.0483 0.088
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2439 1.2762 0.8242 0.296 0.767
Likelihood ratio test=0.09 on 1 df, p=0.7675
n= 22, number of events= 6
============================
TCGA-COAD ATG5
[1] 119
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 4.47 0.485 1.1
strata=LOW 11 6 4.53 0.479 1.1
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7519 2.1211 0.7321 1.027 0.304
Likelihood ratio test=1.1 on 1 df, p=0.2947
n= 22, number of events= 9
============================
TCGA-COAD ACVR1B
[1] 120
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 4.24 0.362 0.925
strata=LOW 11 4 2.76 0.556 0.925
Chisq= 0.9 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7223 2.0592 0.7669 0.942 0.346
Likelihood ratio test=0.9 on 1 df, p=0.3432
n= 22, number of events= 7
============================
TCGA-COAD NT5DC2
[1] 121
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 4.1 0.00225 0.00973
strata=LOW 11 2 1.9 0.00485 0.00973
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1012 1.1065 1.0263 0.099 0.921
Likelihood ratio test=0.01 on 1 df, p=0.9215
n= 22, number of events= 6
============================
TCGA-COAD PIK3CA
[1] 122
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 3.26 2.29 6.11
strata=LOW 11 0 2.74 2.74 6.11
Chisq= 6.1 on 1 degrees of freedom, p= 0.01
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.144e+01 4.891e-10 1.818e+04 -0.001 0.999
Likelihood ratio test=7.99 on 1 df, p=0.004707
n= 22, number of events= 6
============================
TCGA-COAD NUPR1
[1] 123
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 4.55 0.0664 0.174
strata=LOW 11 4 3.45 0.0875 0.174
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3188 1.3755 0.7671 0.416 0.678
Likelihood ratio test=0.17 on 1 df, p=0.676
n= 22, number of events= 8
============================
TCGA-COAD AKT1S1
[1] 124
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 5.71 0.0151 0.0496
strata=LOW 11 3 3.29 0.0262 0.0496
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1702 0.8435 0.7650 -0.223 0.824
Likelihood ratio test=0.05 on 1 df, p=0.8233
n= 22, number of events= 9
============================
TCGA-COAD MIR19A
============================
TCGA-COAD USP7
[1] 125
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.36 0.0925 0.275
strata=LOW 11 2 2.64 0.1532 0.275
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4516 0.6366 0.8685 -0.52 0.603
Likelihood ratio test=0.28 on 1 df, p=0.5954
n= 22, number of events= 7
============================
TCGA-COAD TMSB4Y
[1] 126
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.82 0.236 0.4
strata=LOW 16 5 4.18 0.159 0.4
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5261 1.6923 0.8410 0.626 0.532
Likelihood ratio test=0.42 on 1 df, p=0.5181
n= 27, number of events= 7
============================
TCGA-COAD SIAH2
[1] 127
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.63 0.1094 0.201
strata=LOW 11 5 4.37 0.0909 0.201
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.327 1.387 0.732 0.447 0.655
Likelihood ratio test=0.2 on 1 df, p=0.6514
n= 22, number of events= 8
============================
TCGA-COAD MIR29A
============================
TCGA-COAD CHAC1
[1] 128
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.57 0.0520 0.111
strata=LOW 11 3 3.43 0.0541 0.111
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2580 0.7726 0.7779 -0.332 0.74
Likelihood ratio test=0.11 on 1 df, p=0.7392
n= 22, number of events= 7
============================
TCGA-COAD LINC00616
============================
TCGA-COAD PRKAA2
[1] 129
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.73 0.592 1.66
strata=LOW 11 1 2.27 0.712 1.66
Chisq= 1.7 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.3802 0.2515 1.1574 -1.192 0.233
Likelihood ratio test=1.68 on 1 df, p=0.1952
n= 22, number of events= 5
============================
TCGA-COAD LONP1
[1] 130
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 7 4.92 0.877 1.97
strata=LOW 11 2 4.08 1.059 1.97
Chisq= 2 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.0796 0.3397 0.8060 -1.34 0.18
Likelihood ratio test=2.11 on 1 df, p=0.1461
n= 22, number of events= 9
============================
TCGA-COAD PPARG
[1] 131
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.42 0.591 1.39
strata=LOW 11 6 4.58 0.442 1.39
Chisq= 1.4 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.9844 2.6761 0.8692 1.132 0.257
Likelihood ratio test=1.38 on 1 df, p=0.2405
n= 22, number of events= 8
============================
TCGA-COAD MAPK1
[1] 132
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.99 0.338 0.595
strata=LOW 11 4 5.01 0.202 0.595
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5826 0.5584 0.7660 -0.761 0.447
Likelihood ratio test=0.59 on 1 df, p=0.4438
n= 22, number of events= 8
============================
TCGA-COAD PEX6
[1] 133
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.2 0.013 0.0283
strata=LOW 11 4 3.8 0.011 0.0283
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1383 1.1483 0.8222 0.168 0.866
Likelihood ratio test=0.03 on 1 df, p=0.8665
n= 22, number of events= 7
============================
TCGA-COAD PPARA
[1] 134
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.58 0.0492 0.102
strata=LOW 11 4 4.42 0.0399 0.102
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2443 0.7833 0.7675 -0.318 0.75
Likelihood ratio test=0.1 on 1 df, p=0.7492
n= 22, number of events= 8
============================
TCGA-COAD ACSL4
[1] 135
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 2.84 1.650 2.62
strata=LOW 11 3 5.16 0.906 2.62
Chisq= 2.6 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.1391 0.3201 0.7394 -1.541 0.123
Likelihood ratio test=2.47 on 1 df, p=0.1157
n= 22, number of events= 8
============================
TCGA-COAD ANO6
[1] 136
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.7 0.624 1.74
strata=LOW 11 1 2.3 0.733 1.74
Chisq= 1.7 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.415 0.243 1.160 -1.22 0.223
Likelihood ratio test=1.76 on 1 df, p=0.1849
n= 22, number of events= 5
============================
TCGA-COAD YTHDC2
[1] 137
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.3 0.0390 0.0757
strata=LOW 11 3 2.7 0.0332 0.0757
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2561 1.2919 0.9328 0.275 0.784
Likelihood ratio test=0.08 on 1 df, p=0.7824
n= 22, number of events= 5
============================
TCGA-COAD MIR103A1
============================
TCGA-COAD INTS2
[1] 138
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.53 0.616 1.39
strata=LOW 11 3 4.47 0.485 1.39
Chisq= 1.4 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8885 0.4113 0.7776 -1.143 0.253
Likelihood ratio test=1.32 on 1 df, p=0.2504
n= 22, number of events= 8
============================
TCGA-COAD PTPN6
[1] 139
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 1 2.73 1.100 2.44
strata=LOW 11 5 3.27 0.921 2.44
Chisq= 2.4 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.581 4.861 1.120 1.412 0.158
Likelihood ratio test=2.55 on 1 df, p=0.1105
n= 22, number of events= 6
============================
TCGA-COAD SMAD7
[1] 140
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.53 0.662 1.72
strata=LOW 11 5 3.47 0.674 1.72
Chisq= 1.7 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.1111 3.0377 0.8857 1.254 0.21
Likelihood ratio test=1.68 on 1 df, p=0.1948
n= 22, number of events= 7
============================
TCGA-COAD ATG16L1
[1] 141
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.4 0.0477 0.0945
strata=LOW 11 4 3.6 0.0451 0.0945
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2364 1.2666 0.7704 0.307 0.759
Likelihood ratio test=0.09 on 1 df, p=0.758
n= 22, number of events= 7
============================
TCGA-COAD LINC00976
[1] 142
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.95 0.000793 0.00159
strata=LOW 11 3 3.05 0.000767 0.00159
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.03296 0.96757 0.82555 -0.04 0.968
Likelihood ratio test=0 on 1 df, p=0.9681
n= 22, number of events= 6
============================
TCGA-COAD H19
[1] 143
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.57 0.0398 0.127
strata=LOW 11 2 2.43 0.0751 0.127
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3096 0.7337 0.8705 -0.356 0.722
Likelihood ratio test=0.13 on 1 df, p=0.718
n= 22, number of events= 7
============================
TCGA-COAD FADS1
[1] 144
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.81 0.370 0.846
strata=LOW 11 3 4.19 0.337 0.846
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6926 0.5003 0.7676 -0.902 0.367
Likelihood ratio test=0.82 on 1 df, p=0.3638
n= 22, number of events= 8
============================
TCGA-COAD CHP1
[1] 145
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.36 0.0382 0.0881
strata=LOW 11 4 3.64 0.0352 0.0881
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2437 1.2760 0.8229 0.296 0.767
Likelihood ratio test=0.09 on 1 df, p=0.7674
n= 22, number of events= 7
============================
TCGA-COAD PRR5
[1] 146
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 5.96 0.156 0.697
strata=LOW 11 3 2.04 0.457 0.697
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6718 1.9578 0.8197 0.82 0.412
Likelihood ratio test=0.66 on 1 df, p=0.4167
n= 22, number of events= 8
============================
TCGA-COAD CFL1
[1] 147
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 4.24 0.365 0.935
strata=LOW 11 5 3.76 0.412 0.935
Chisq= 0.9 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7266 2.0680 0.7674 0.947 0.344
Likelihood ratio test=0.91 on 1 df, p=0.3407
n= 22, number of events= 8
============================
TCGA-COAD MIR382
============================
TCGA-COAD LAMP2
[1] 148
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 1.43 1.727 3.44
strata=LOW 11 2 3.57 0.691 3.44
Chisq= 3.4 on 1 degrees of freedom, p= 0.06
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.143e+01 4.950e-10 2.352e+04 -0.001 0.999
Likelihood ratio test=4.61 on 1 df, p=0.03188
n= 22, number of events= 5
============================
TCGA-COAD PTPN14
[1] 149
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 4.93 0.233 0.703
strata=LOW 11 2 3.07 0.374 0.703
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7029 0.4952 0.8538 -0.823 0.41
Likelihood ratio test=0.73 on 1 df, p=0.3924
n= 22, number of events= 8
============================
TCGA-COAD AGPAT3
[1] 150
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.08 0.00228 0.005
strata=LOW 11 4 3.92 0.00180 0.005
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.05952 1.06132 0.84171 0.071 0.944
Likelihood ratio test=0 on 1 df, p=0.9436
n= 22, number of events= 7
============================
TCGA-COAD STING1
[1] 151
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 4.66 0.0947 0.237
strata=LOW 11 5 4.34 0.1018 0.237
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3657 1.4415 0.7552 0.484 0.628
Likelihood ratio test=0.24 on 1 df, p=0.6239
n= 22, number of events= 9
============================
TCGA-COAD ABCC1
[1] 152
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.53 0.610 1.11
strata=LOW 11 3 4.47 0.482 1.11
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7587 0.4683 0.7363 -1.03 0.303
Likelihood ratio test=1.1 on 1 df, p=0.2933
n= 22, number of events= 8
============================
TCGA-COAD IFNA5
============================
TCGA-COAD MIR140
============================
TCGA-COAD MYB
[1] 153
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.67 0.760 1.62
strata=LOW 11 5 3.33 0.838 1.62
Chisq= 1.6 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.0297 2.8002 0.8429 1.222 0.222
Likelihood ratio test=1.66 on 1 df, p=0.1972
n= 22, number of events= 7
============================
TCGA-COAD IFNA6
============================
TCGA-COAD IFNA14
============================
TCGA-COAD BDNF-AS
[1] 154
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.71 0.184 0.413
strata=LOW 11 4 3.29 0.151 0.413
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5866 1.7979 0.9253 0.634 0.526
Likelihood ratio test=0.41 on 1 df, p=0.5212
n= 22, number of events= 6
============================
TCGA-COAD TRIB2
[1] 155
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.36 0.120 0.328
strata=LOW 11 2 2.64 0.154 0.328
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5191 0.5951 0.9168 -0.566 0.571
Likelihood ratio test=0.33 on 1 df, p=0.5667
n= 22, number of events= 6
============================
TCGA-COAD MALAT1
[1] 156
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.46 0.0859 0.249
strata=LOW 11 2 2.54 0.1167 0.249
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4622 0.6299 0.9339 -0.495 0.621
Likelihood ratio test=0.25 on 1 df, p=0.617
n= 22, number of events= 6
============================
TCGA-COAD FH
[1] 157
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.97 0.236 0.553
strata=LOW 11 4 3.03 0.308 0.553
Chisq= 0.6 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5661 1.7613 0.7711 0.734 0.463
Likelihood ratio test=0.55 on 1 df, p=0.4597
n= 22, number of events= 7
============================
TCGA-COAD PEX10
[1] 158
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.17 0.00948 0.0264
strata=LOW 11 3 2.83 0.01064 0.0264
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1497 1.1614 0.9217 0.162 0.871
Likelihood ratio test=0.03 on 1 df, p=0.8717
n= 22, number of events= 6
============================
TCGA-COAD SCD
[1] 159
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.29 0.117 0.289
strata=LOW 11 3 3.71 0.135 0.289
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4097 0.6639 0.7667 -0.534 0.593
Likelihood ratio test=0.29 on 1 df, p=0.5908
n= 22, number of events= 8
============================
TCGA-COAD FTL
[1] 160
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.3 0.148 0.285
strata=LOW 11 4 4.7 0.104 0.285
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4077 0.6651 0.7693 -0.53 0.596
Likelihood ratio test=0.28 on 1 df, p=0.5937
n= 22, number of events= 8
============================
TCGA-COAD TSC1
[1] 161
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.06 0.218 0.522
strata=LOW 11 3 3.94 0.225 0.522
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5498 0.5771 0.7698 -0.714 0.475
Likelihood ratio test=0.52 on 1 df, p=0.4721
n= 22, number of events= 8
============================
TCGA-COAD BRD3
[1] 162
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.86 0.336 0.902
strata=LOW 11 2 3.14 0.413 0.902
Chisq= 0.9 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8150 0.4426 0.8799 -0.926 0.354
Likelihood ratio test=0.91 on 1 df, p=0.3397
n= 22, number of events= 7
============================
TCGA-COAD SLC16A1
[1] 163
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.33 0.196 0.372
strata=LOW 11 3 3.68 0.124 0.372
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5536 0.5749 0.9193 -0.602 0.547
Likelihood ratio test=0.37 on 1 df, p=0.5422
n= 22, number of events= 6
============================
TCGA-COAD MIR132
============================
TCGA-COAD MIR375
============================
TCGA-COAD MIOX
[1] 164
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.12 0.00693 0.0151
strata=LOW 11 2 1.88 0.00782 0.0151
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1247 1.1328 1.0137 0.123 0.902
Likelihood ratio test=0.02 on 1 df, p=0.9021
n= 22, number of events= 4
============================
TCGA-COAD ATXN8OS
============================
TCGA-COAD KLHDC3
[1] 165
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 1.83 0.01526 0.0283
strata=LOW 11 3 3.17 0.00883 0.0283
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1682 0.8452 1.0016 -0.168 0.867
Likelihood ratio test=0.03 on 1 df, p=0.8667
n= 22, number of events= 5
============================
TCGA-COAD MICU1
[1] 166
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.56 0.805 1.45
strata=LOW 11 4 5.44 0.380 1.45
Chisq= 1.4 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.0184 0.3612 0.8807 -1.156 0.248
Likelihood ratio test=1.44 on 1 df, p=0.2304
n= 22, number of events= 8
============================
TCGA-COAD CBS
[1] 167
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.95 0.370 1.12
strata=LOW 11 1 2.05 0.534 1.12
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.1662 0.3115 1.1637 -1.002 0.316
Likelihood ratio test=1.16 on 1 df, p=0.2809
n= 22, number of events= 5
============================
TCGA-COAD HUWE1
[1] 168
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.27 0.918 2.45
strata=LOW 11 1 2.73 1.098 2.45
Chisq= 2.4 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.5881 0.2043 1.1223 -1.415 0.157
Likelihood ratio test=2.56 on 1 df, p=0.1099
n= 22, number of events= 6
============================
TCGA-COAD LINC00472
[1] 169
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.05 0.221 0.613
strata=LOW 11 2 2.95 0.304 0.613
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6725 0.5104 0.8744 -0.769 0.442
Likelihood ratio test=0.63 on 1 df, p=0.4292
n= 22, number of events= 7
============================
TCGA-COAD FGF21
============================
TCGA-COAD MIR34A
============================
TCGA-COAD IDH1
[1] 170
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.17 0.00952 0.0202
strata=LOW 11 5 4.83 0.00626 0.0202
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1163 1.1233 0.8175 0.142 0.887
Likelihood ratio test=0.02 on 1 df, p=0.8869
n= 22, number of events= 8
============================
TCGA-COAD GSK3B
[1] 171
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.17 0.216 0.459
strata=LOW 11 2 2.83 0.242 0.459
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5793 0.5603 0.8669 -0.668 0.504
Likelihood ratio test=0.47 on 1 df, p=0.4929
n= 22, number of events= 6
============================
TCGA-COAD KDM4A
[1] 172
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.46 0.0622 0.124
strata=LOW 11 4 3.54 0.0610 0.124
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2693 1.3090 0.7666 0.351 0.725
Likelihood ratio test=0.12 on 1 df, p=0.7241
n= 22, number of events= 7
============================
TCGA-COAD PEX12
[1] 173
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.17 0.218 0.401
strata=LOW 11 3 3.83 0.180 0.401
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4805 0.6185 0.7664 -0.627 0.531
Likelihood ratio test=0.4 on 1 df, p=0.5279
n= 22, number of events= 7
============================
TCGA-COAD IDO1
[1] 174
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 4.12 0.00372 0.00773
strata=LOW 11 5 4.88 0.00315 0.00773
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.06234 1.06433 0.70920 0.088 0.93
Likelihood ratio test=0.01 on 1 df, p=0.93
n= 22, number of events= 9
============================
TCGA-COAD BCAT2
[1] 175
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 4.96 0.185 0.728
strata=LOW 11 3 2.04 0.448 0.728
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7168 2.0479 0.8545 0.839 0.402
Likelihood ratio test=0.7 on 1 df, p=0.4042
n= 22, number of events= 7
============================
TCGA-COAD ADAM23
[1] 176
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.06 0.287 0.6
strata=LOW 11 2 2.94 0.300 0.6
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6653 0.5141 0.8737 -0.761 0.446
Likelihood ratio test=0.61 on 1 df, p=0.4339
n= 22, number of events= 6
============================
TCGA-COAD PEX3
[1] 177
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.6 0.140 0.294
strata=LOW 11 3 2.4 0.152 0.294
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4917 1.6352 0.9163 0.537 0.592
Likelihood ratio test=0.29 on 1 df, p=0.5873
n= 22, number of events= 5
============================
TCGA-COAD ATP5MC3
[1] 178
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.95 0.305 0.762
strata=LOW 11 4 3.05 0.295 0.762
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7867 2.1961 0.9229 0.852 0.394
Likelihood ratio test=0.75 on 1 df, p=0.3878
n= 22, number of events= 6
============================
TCGA-COAD AQP5
[1] 179
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.12 1.139 1.8
strata=LOW 11 4 5.88 0.603 1.8
Chisq= 1.8 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8866 0.4121 0.6814 -1.301 0.193
Likelihood ratio test=1.69 on 1 df, p=0.1931
n= 22, number of events= 9
============================
TCGA-COAD ADAMTS9-AS1
[1] 180
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.16 0.169 0.492
strata=LOW 11 2 2.84 0.247 0.492
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6097 0.5435 0.8816 -0.692 0.489
Likelihood ratio test=0.5 on 1 df, p=0.4787
n= 22, number of events= 7
============================
TCGA-COAD ACSL3
[1] 181
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.17 0.164 0.396
strata=LOW 11 3 3.83 0.179 0.396
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4770 0.6207 0.7648 -0.624 0.533
Likelihood ratio test=0.39 on 1 df, p=0.5301
n= 22, number of events= 8
============================
TCGA-COAD DDR2
[1] 182
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 4.15 0.829 2.37
strata=LOW 11 1 2.85 1.205 2.37
Chisq= 2.4 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.5468 0.2129 1.1034 -1.402 0.161
Likelihood ratio test=2.6 on 1 df, p=0.1067
n= 22, number of events= 7
============================
TCGA-COAD TERT
[1] 183
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.9 0.926 2.98
strata=LOW 11 4 2.1 1.721 2.98
Chisq= 3 on 1 degrees of freedom, p= 0.08
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.718 5.571 1.120 1.534 0.125
Likelihood ratio test=3.04 on 1 df, p=0.0811
n= 22, number of events= 6
============================
TCGA-COAD IFNA7
============================
TCGA-COAD ECH1
[1] 184
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.6 0.139 0.295
strata=LOW 11 4 3.4 0.106 0.295
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4947 1.6399 0.9201 0.538 0.591
Likelihood ratio test=0.3 on 1 df, p=0.5867
n= 22, number of events= 6
============================
TCGA-COAD CS
[1] 185
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.21 0.0136 0.0295
strata=LOW 11 3 2.79 0.0156 0.0295
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1406 1.1510 0.8198 0.172 0.864
Likelihood ratio test=0.03 on 1 df, p=0.8638
n= 22, number of events= 6
============================
TCGA-COAD AMN
[1] 186
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.18 0.437 0.965
strata=LOW 11 4 2.82 0.493 0.965
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8391 2.3142 0.8776 0.956 0.339
Likelihood ratio test=0.97 on 1 df, p=0.3241
n= 22, number of events= 6
============================
TCGA-COAD DUOX2
[1] 187
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.04 0.300 0.625
strata=LOW 11 2 2.96 0.309 0.625
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6792 0.5070 0.8747 -0.777 0.437
Likelihood ratio test=0.64 on 1 df, p=0.4247
n= 22, number of events= 6
============================
TCGA-COAD MBOAT1
[1] 188
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.01 0.341 0.876
strata=LOW 11 3 1.99 0.517 0.876
Chisq= 0.9 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8408 2.3182 0.9232 0.911 0.362
Likelihood ratio test=0.85 on 1 df, p=0.356
n= 22, number of events= 5
============================
TCGA-COAD RNF113A
[1] 189
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 1 2.63 1.01 2.2
strata=LOW 11 4 2.37 1.13 2.2
Chisq= 2.2 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.530 4.619 1.129 1.355 0.175
Likelihood ratio test=2.32 on 1 df, p=0.1276
n= 22, number of events= 5
============================
TCGA-COAD MIR138-1
============================
TCGA-COAD MIR144
============================
TCGA-COAD P4HB
[1] 190
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.46 0.0849 0.168
strata=LOW 11 3 2.54 0.0820 0.168
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3724 1.4513 0.9150 0.407 0.684
Likelihood ratio test=0.17 on 1 df, p=0.6811
n= 22, number of events= 5
============================
TCGA-COAD MIR338
============================
TCGA-COAD PTGS2
[1] 191
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.15 1.60 3.52
strata=LOW 11 0 1.85 1.85 3.52
Chisq= 3.5 on 1 degrees of freedom, p= 0.06
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.111e+01 6.785e-10 2.028e+04 -0.001 0.999
Likelihood ratio test=5.05 on 1 df, p=0.02466
n= 22, number of events= 4
============================
TCGA-COAD ASAH2
[1] 192
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 1 1.99 0.491 0.827
strata=LOW 11 5 4.01 0.243 0.827
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.9822 2.6704 1.1231 0.875 0.382
Likelihood ratio test=0.91 on 1 df, p=0.3411
n= 22, number of events= 6
============================
TCGA-COAD MIR522
============================
TCGA-COAD GALNT14
[1] 193
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 2.07 4.17 6.76
strata=LOW 11 1 3.93 2.19 6.76
Chisq= 6.8 on 1 degrees of freedom, p= 0.009
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.45008 0.08629 1.13638 -2.156 0.0311
Likelihood ratio test=6.61 on 1 df, p=0.01013
n= 22, number of events= 6
============================
TCGA-COAD KDM4C
[1] 194
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 1 2.38 0.798 1.61
strata=LOW 11 5 3.62 0.523 1.61
Chisq= 1.6 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.341 3.822 1.132 1.184 0.236
Likelihood ratio test=1.72 on 1 df, p=0.1895
n= 22, number of events= 6
============================
TCGA-COAD FXN
[1] 195
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 4.99 0.204 0.693
strata=LOW 11 2 3.01 0.339 0.693
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7129 0.4902 0.8734 -0.816 0.414
Likelihood ratio test=0.71 on 1 df, p=0.4007
n= 22, number of events= 8
============================
TCGA-COAD MEF2C
[1] 196
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 1.28 2.294 4.03
strata=LOW 11 2 3.72 0.793 4.03
Chisq= 4 on 1 degrees of freedom, p= 0.04
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.155e+01 4.392e-10 2.368e+04 -0.001 0.999
Likelihood ratio test=5.11 on 1 df, p=0.02375
n= 22, number of events= 5
============================
TCGA-COAD MDM2
[1] 197
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 4.89 0.733 3.04
strata=LOW 11 4 2.11 1.701 3.04
Chisq= 3 on 1 degrees of freedom, p= 0.08
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.767 5.852 1.136 1.555 0.12
Likelihood ratio test=3.12 on 1 df, p=0.07751
n= 22, number of events= 7
============================
TCGA-COAD MAP3K14
[1] 198
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.83 0.488 0.85
strata=LOW 11 4 5.17 0.267 0.85
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7069 0.4931 0.7814 -0.905 0.366
Likelihood ratio test=0.83 on 1 df, p=0.3618
n= 22, number of events= 8
============================
TCGA-COAD MDM4
[1] 199
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 4.71 0.106 0.296
strata=LOW 11 4 3.29 0.151 0.296
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4196 1.5214 0.7765 0.54 0.589
Likelihood ratio test=0.3 on 1 df, p=0.5868
n= 22, number of events= 8
============================
TCGA-COAD ASMTL-AS1
[1] 200
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.26 0.169 0.451
strata=LOW 11 2 2.74 0.201 0.451
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6091 0.5438 0.9204 -0.662 0.508
Likelihood ratio test=0.45 on 1 df, p=0.5027
n= 22, number of events= 6
============================
TCGA-COAD NEAT1
[1] 201
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.1 0.392 0.842
strata=LOW 11 4 2.9 0.420 0.842
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7865 2.1957 0.8778 0.896 0.37
Likelihood ratio test=0.85 on 1 df, p=0.3559
n= 22, number of events= 6
============================
TCGA-COAD COPZ1
[1] 202
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.37 0.556 1.08
strata=LOW 11 6 4.63 0.405 1.08
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8507 2.3413 0.8409 1.012 0.312
Likelihood ratio test=1.13 on 1 df, p=0.2886
n= 22, number of events= 8
============================
TCGA-COAD PLIN2
[1] 203
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.47 0.0906 0.183
strata=LOW 11 5 4.53 0.0495 0.183
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3929 1.4812 0.9228 0.426 0.67
Likelihood ratio test=0.18 on 1 df, p=0.6673
n= 22, number of events= 7
============================
TCGA-COAD FADS2
[1] 204
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 4.83 0.285 0.817
strata=LOW 11 2 3.17 0.433 0.817
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7475 0.4735 0.8454 -0.884 0.377
Likelihood ratio test=0.85 on 1 df, p=0.3567
n= 22, number of events= 8
============================
TCGA-COAD MIR7-1
============================
TCGA-COAD TXN
[1] 205
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 1 2.33 0.759 1.84
strata=LOW 11 4 2.67 0.661 1.84
Chisq= 1.8 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.452 4.271 1.162 1.25 0.211
Likelihood ratio test=1.85 on 1 df, p=0.174
n= 22, number of events= 5
============================
TCGA-COAD MIR302A
============================
TCGA-COAD EGLN2
[1] 206
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 4.46 0.0476 0.122
strata=LOW 11 4 3.54 0.0600 0.122
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2674 1.3066 0.7667 0.349 0.727
Likelihood ratio test=0.12 on 1 df, p=0.726
n= 22, number of events= 8
============================
TCGA-COAD NCOA3
[1] 207
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.35 0.178 0.481
strata=LOW 11 2 2.65 0.158 0.481
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6947 0.4992 1.0198 -0.681 0.496
Likelihood ratio test=0.46 on 1 df, p=0.4992
n= 22, number of events= 5
============================
TCGA-COAD SREBF1
[1] 208
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.75 0.0170 0.0518
strata=LOW 11 2 2.25 0.0283 0.0518
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2078 0.8124 0.9149 -0.227 0.82
Likelihood ratio test=0.05 on 1 df, p=0.8193
n= 22, number of events= 6
============================
TCGA-COAD LINC01134
[1] 209
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 4.41 0.453 1.25
strata=LOW 11 5 3.59 0.557 1.25
Chisq= 1.2 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8388 2.3136 0.7712 1.088 0.277
Likelihood ratio test=1.2 on 1 df, p=0.2742
n= 22, number of events= 8
============================
TCGA-COAD MYCN
[1] 210
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.83 0.01003 0.0175
strata=LOW 11 4 4.17 0.00681 0.0175
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1031 0.9020 0.7796 -0.132 0.895
Likelihood ratio test=0.02 on 1 df, p=0.895
n= 22, number of events= 7
============================
TCGA-COAD IFNA4
============================
TCGA-COAD DPEP1
[1] 211
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.74 0.577 1.31
strata=LOW 11 2 3.26 0.486 1.31
Chisq= 1.3 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.2157 0.2965 1.1266 -1.079 0.281
Likelihood ratio test=1.42 on 1 df, p=0.2332
n= 22, number of events= 6
============================
TCGA-COAD VDAC2
[1] 212
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.91 0.212 0.518
strata=LOW 11 5 4.09 0.203 0.518
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5589 1.7487 0.7856 0.711 0.477
Likelihood ratio test=0.51 on 1 df, p=0.475
n= 22, number of events= 8
============================
TCGA-COAD PCBP2-OT1
[1] 213
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 4.06 1.04 2.73
strata=LOW 21 6 3.94 1.07 2.73
Chisq= 2.7 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.702 5.485 1.124 1.514 0.13
Likelihood ratio test=3.12 on 1 df, p=0.07753
n= 32, number of events= 8
============================
TCGA-COAD KEAP1
[1] 214
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.53 0.0864 0.247
strata=LOW 11 2 2.47 0.0887 0.247
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5764 0.5619 1.1748 -0.491 0.624
Likelihood ratio test=0.26 on 1 df, p=0.6097
n= 22, number of events= 5
============================
TCGA-COAD RPL8
[1] 215
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.54 0.0844 0.173
strata=LOW 11 3 3.46 0.0618 0.173
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3791 0.6845 0.9168 -0.413 0.679
Likelihood ratio test=0.17 on 1 df, p=0.6764
n= 22, number of events= 6
============================
TCGA-COAD ALOX12
[1] 216
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.99 0.258 0.52
strata=LOW 11 4 5.01 0.205 0.52
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5240 0.5922 0.7344 -0.713 0.476
Likelihood ratio test=0.53 on 1 df, p=0.4685
n= 22, number of events= 9
============================
TCGA-COAD ACSF2
[1] 217
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.86 0.260 0.619
strata=LOW 11 4 3.14 0.238 0.619
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7101 2.0342 0.9205 0.771 0.44
Likelihood ratio test=0.61 on 1 df, p=0.4344
n= 22, number of events= 6
============================
TCGA-COAD KDM5A
[1] 218
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.29 0.155 0.397
strata=LOW 11 3 3.71 0.137 0.397
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5421 0.5815 0.8684 -0.624 0.532
Likelihood ratio test=0.39 on 1 df, p=0.533
n= 22, number of events= 7
============================
TCGA-COAD NRAS
[1] 219
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.99 5.74e-05 0.000119
strata=LOW 11 4 4.01 4.27e-05 0.000119
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.009084 0.990957 0.832902 -0.011 0.991
Likelihood ratio test=0 on 1 df, p=0.9913
n= 22, number of events= 7
============================
TCGA-COAD MIR30E
============================
TCGA-COAD OGFRP1
[1] 220
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 4.09 0.00204 0.00421
strata=LOW 11 4 3.91 0.00213 0.00421
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.04604 1.04711 0.70996 0.065 0.948
Likelihood ratio test=0 on 1 df, p=0.9483
n= 22, number of events= 8
============================
TCGA-COAD TF
[1] 221
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.58 0.0390 0.0913
strata=LOW 11 4 4.42 0.0404 0.0913
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2147 0.8068 0.7115 -0.302 0.763
Likelihood ratio test=0.09 on 1 df, p=0.7631
n= 22, number of events= 9
============================
TCGA-COAD ETV4
[1] 222
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.51 0.634 1.8
strata=LOW 11 1 2.49 0.893 1.8
Chisq= 1.8 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.3924 0.2485 1.1219 -1.241 0.215
Likelihood ratio test=1.93 on 1 df, p=0.1651
n= 22, number of events= 6
============================
TCGA-COAD PLA2G6
[1] 223
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.84 0.00934 0.018
strata=LOW 11 4 4.16 0.00636 0.018
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1105 0.8954 0.8237 -0.134 0.893
Likelihood ratio test=0.02 on 1 df, p=0.8933
n= 22, number of events= 7
============================
TCGA-COAD POR
[1] 224
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 4.16 0.00627 0.0156
strata=LOW 11 3 2.84 0.00919 0.0156
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.09604 1.10080 0.76827 0.125 0.901
Likelihood ratio test=0.02 on 1 df, p=0.9008
n= 22, number of events= 7
============================
TCGA-COAD BRPF1
[1] 225
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.25 0.0187 0.035
strata=LOW 11 4 3.75 0.0162 0.035
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1431 1.1538 0.7653 0.187 0.852
Likelihood ratio test=0.04 on 1 df, p=0.8513
n= 22, number of events= 7
============================
TCGA-COAD TMBIM4
[1] 226
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.23 0.471 1.03
strata=LOW 11 4 2.77 0.551 1.03
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8524 2.3452 0.8673 0.983 0.326
Likelihood ratio test=1.03 on 1 df, p=0.3096
n= 22, number of events= 6
============================
TCGA-COAD KRAS
[1] 227
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 1 2.4 0.819 1.58
strata=LOW 11 4 2.6 0.758 1.58
Chisq= 1.6 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.313 3.719 1.120 1.173 0.241
Likelihood ratio test=1.71 on 1 df, p=0.1912
n= 22, number of events= 5
============================
TCGA-COAD AHCY
[1] 228
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.2 0.0179 0.0319
strata=LOW 11 4 3.8 0.0103 0.0319
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1630 1.1771 0.9133 0.179 0.858
Likelihood ratio test=0.03 on 1 df, p=0.8576
n= 22, number of events= 6
============================
TCGA-COAD MIR34C
============================
TCGA-COAD ATG3
[1] 229
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.09 0.382 0.795
strata=LOW 11 5 3.91 0.302 0.795
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7577 2.1333 0.8698 0.871 0.384
Likelihood ratio test=0.81 on 1 df, p=0.3689
n= 22, number of events= 7
============================
TCGA-COAD MIR30B
============================
TCGA-COAD LYRM1
[1] 230
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 1.36 0.297 0.55
strata=LOW 11 2 2.64 0.154 0.55
Chisq= 0.6 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8848 0.4128 1.2307 -0.719 0.472
Likelihood ratio test=0.55 on 1 df, p=0.4572
n= 22, number of events= 4
============================
TCGA-COAD SIRT6
[1] 231
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.7 0.784 2.1
strata=LOW 11 5 3.3 0.880 2.1
Chisq= 2.1 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.2038 3.3329 0.8776 1.372 0.17
Likelihood ratio test=2.03 on 1 df, p=0.1542
n= 22, number of events= 7
============================
TCGA-COAD KMT2D
[1] 232
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.3 0.88 2.38
strata=LOW 11 1 2.7 1.07 2.38
Chisq= 2.4 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.5770 0.2066 1.1261 -1.4 0.161
Likelihood ratio test=2.49 on 1 df, p=0.1142
n= 22, number of events= 6
============================
TCGA-COAD LPIN1
[1] 233
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.39 0.764 1.66
strata=LOW 11 3 4.61 0.562 1.66
Chisq= 1.7 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.9555 0.3846 0.7682 -1.244 0.214
Likelihood ratio test=1.56 on 1 df, p=0.2118
n= 22, number of events= 8
============================
TCGA-COAD MBOAT2
[1] 234
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.24 0.0255 0.0461
strata=LOW 11 3 2.76 0.0206 0.0461
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1958 1.2163 0.9132 0.214 0.83
Likelihood ratio test=0.05 on 1 df, p=0.8292
n= 22, number of events= 5
============================
TCGA-COAD KDM3B
[1] 235
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.07 0.279 0.707
strata=LOW 11 2 2.93 0.293 0.707
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7512 0.4718 0.9141 -0.822 0.411
Likelihood ratio test=0.69 on 1 df, p=0.4049
n= 22, number of events= 6
============================
TCGA-COAD ARHGEF26-AS1
[1] 236
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.18 0.0107 0.0229
strata=LOW 11 3 2.82 0.0121 0.0229
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1236 1.1316 0.8175 0.151 0.88
Likelihood ratio test=0.02 on 1 df, p=0.8798
n= 22, number of events= 6
============================
TCGA-COAD MIR9-1
============================
TCGA-COAD AIFM2
[1] 237
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.05 0.364 0.746
strata=LOW 11 4 2.95 0.378 0.746
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7336 2.0825 0.8682 0.845 0.398
Likelihood ratio test=0.76 on 1 df, p=0.3837
n= 22, number of events= 6
============================
TCGA-COAD PRDX1
[1] 238
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.88 0.00538 0.0107
strata=LOW 11 4 4.12 0.00375 0.0107
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.08592 0.91766 0.83091 -0.103 0.918
Likelihood ratio test=0.01 on 1 df, p=0.9176
n= 22, number of events= 7
============================
TCGA-COAD FOXO4
[1] 239
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.94 0.001194 0.00248
strata=LOW 11 4 4.06 0.000865 0.00248
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.04183 0.95904 0.84017 -0.05 0.96
Likelihood ratio test=0 on 1 df, p=0.9603
n= 22, number of events= 7
============================
TCGA-COAD BMAL1
[1] 240
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 4.08 0.00163 0.00336
strata=LOW 11 4 3.92 0.00169 0.00336
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.0412 1.0421 0.7110 0.058 0.954
Likelihood ratio test=0 on 1 df, p=0.9538
n= 22, number of events= 8
============================
TCGA-COAD MIR127
============================
TCGA-COAD TGFBR1
[1] 241
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 3.75 1.34 3.42
strata=LOW 11 1 3.25 1.55 3.42
Chisq= 3.4 on 1 degrees of freedom, p= 0.06
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.7877 0.1673 1.0982 -1.628 0.104
Likelihood ratio test=3.64 on 1 df, p=0.05639
n= 22, number of events= 7
============================
TCGA-COAD NR1D2
[1] 242
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.2 0.0130 0.028
strata=LOW 11 4 3.8 0.0109 0.028
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1372 1.1470 0.8198 0.167 0.867
Likelihood ratio test=0.03 on 1 df, p=0.8672
n= 22, number of events= 7
============================
TCGA-COAD FZD7
[1] 243
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.87 0.330 0.643
strata=LOW 11 3 4.13 0.309 0.643
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5798 0.5600 0.7328 -0.791 0.429
Likelihood ratio test=0.65 on 1 df, p=0.4208
n= 22, number of events= 8
============================
TCGA-COAD G6PD
[1] 244
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.37 0.165 0.314
strata=LOW 11 2 2.63 0.149 0.314
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5069 0.6024 0.9138 -0.555 0.579
Likelihood ratio test=0.31 on 1 df, p=0.5747
n= 22, number of events= 5
============================
TCGA-COAD HRAS
[1] 245
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.73 0.0155 0.0567
strata=LOW 11 2 2.27 0.0323 0.0567
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2141 0.8073 0.9005 -0.238 0.812
Likelihood ratio test=0.06 on 1 df, p=0.8105
n= 22, number of events= 7
============================
TCGA-COAD SLC38A1
[1] 246
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.86 0.457 1.32
strata=LOW 11 1 2.14 0.610 1.32
Chisq= 1.3 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.2451 0.2879 1.1558 -1.077 0.281
Likelihood ratio test=1.36 on 1 df, p=0.244
n= 22, number of events= 5
============================
TCGA-COAD SLC39A14
[1] 247
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.07 0.00154 0.00345
strata=LOW 11 4 3.93 0.00120 0.00345
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.05002 1.05129 0.85223 0.059 0.953
Likelihood ratio test=0 on 1 df, p=0.9532
n= 22, number of events= 7
============================
TCGA-COAD MIR21
============================
TCGA-COAD MIR1-1
============================
TCGA-COAD PROM2
[1] 248
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 5.4 0.0298 0.0844
strata=LOW 11 4 3.6 0.0447 0.0844
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2094 1.2330 0.7220 0.29 0.772
Likelihood ratio test=0.08 on 1 df, p=0.7718
n= 22, number of events= 9
============================
TCGA-COAD NFE2L2
[1] 249
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 4.19 0.00851 0.0185
strata=LOW 11 5 4.81 0.00741 0.0185
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.09764 1.10256 0.71886 0.136 0.892
Likelihood ratio test=0.02 on 1 df, p=0.892
n= 22, number of events= 9
============================
TCGA-COAD GABARAPL1
[1] 250
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.42 1.029 2
strata=LOW 11 2 3.58 0.696 2
Chisq= 2 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.4550 0.2334 1.1197 -1.299 0.194
Likelihood ratio test=2.13 on 1 df, p=0.1444
n= 22, number of events= 6
============================
TCGA-COAD MIR335
============================
TCGA-COAD PTEN
[1] 251
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.76 0.0156 0.0337
strata=LOW 11 4 4.24 0.0138 0.0337
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1404 0.8690 0.7650 -0.184 0.854
Likelihood ratio test=0.03 on 1 df, p=0.854
n= 22, number of events= 8
============================
TCGA-COAD PARP4
[1] 252
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.32 0.0311 0.0595
strata=LOW 11 6 5.68 0.0182 0.0595
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1864 1.2050 0.7656 0.244 0.808
Likelihood ratio test=0.06 on 1 df, p=0.8069
n= 22, number of events= 9
============================
TCGA-COAD MS4A15
[1] 253
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 2.89 1.53 3.02
strata=LOW 11 2 4.11 1.08 3.02
Chisq= 3 on 1 degrees of freedom, p= 0.08
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.7121 0.1805 1.1034 -1.552 0.121
Likelihood ratio test=3.27 on 1 df, p=0.07071
n= 22, number of events= 7
============================
TCGA-COAD TIMM9
[1] 254
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.8 0.513 0.965
strata=LOW 11 3 4.2 0.342 0.965
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8281 0.4369 0.8671 -0.955 0.34
Likelihood ratio test=0.97 on 1 df, p=0.3237
n= 22, number of events= 7
============================
TCGA-COAD PARP3
[1] 255
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.71 0.0178 0.0469
strata=LOW 11 3 3.29 0.0254 0.0469
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1644 0.8484 0.7596 -0.216 0.829
Likelihood ratio test=0.05 on 1 df, p=0.8278
n= 22, number of events= 8
============================
TCGA-COAD WIPI1
[1] 256
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 1 1.9 0.423 0.828
strata=LOW 11 4 3.1 0.259 0.828
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.018 2.766 1.165 0.874 0.382
Likelihood ratio test=0.87 on 1 df, p=0.3508
n= 22, number of events= 5
============================
TCGA-COAD SNX5
[1] 257
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 1 3.03 1.36 2.74
strata=LOW 11 6 3.97 1.03 2.74
Chisq= 2.7 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.631 5.107 1.096 1.487 0.137
Likelihood ratio test=2.99 on 1 df, p=0.08389
n= 22, number of events= 7
============================
TCGA-COAD LINC00239
[1] 258
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 4.6 0.559 1.67
strata=LOW 11 5 3.4 0.757 1.67
Chisq= 1.7 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.9643 2.6229 0.7733 1.247 0.212
Likelihood ratio test=1.57 on 1 df, p=0.2106
n= 22, number of events= 8
============================
TCGA-COAD PIEZO1
[1] 259
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.24 0.176 0.465
strata=LOW 11 2 2.76 0.208 0.465
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6142 0.5411 0.9150 -0.671 0.502
Likelihood ratio test=0.46 on 1 df, p=0.4966
n= 22, number of events= 6
============================
TCGA-COAD AKR1C2
[1] 260
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 4.13 1.10 3.68
strata=LOW 11 4 1.87 2.44 3.68
Chisq= 3.7 on 1 degrees of freedom, p= 0.06
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.5553 4.7363 0.8838 1.76 0.0785
Likelihood ratio test=3.34 on 1 df, p=0.06776
n= 22, number of events= 6
============================
TCGA-COAD MIR4443
============================
TCGA-COAD SLC16A1-AS1
[1] 261
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.11 0.194 0.467
strata=LOW 11 3 3.89 0.204 0.467
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5201 0.5945 0.7694 -0.676 0.499
Likelihood ratio test=0.46 on 1 df, p=0.4962
n= 22, number of events= 8
============================
TCGA-COAD FAR1
[1] 262
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.68 0.765 2.28
strata=LOW 11 4 2.32 1.210 2.28
Chisq= 2.3 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.540 4.665 1.121 1.374 0.17
Likelihood ratio test=2.4 on 1 df, p=0.1215
n= 22, number of events= 6
============================
TCGA-COAD CISD2
[1] 263
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.66 0.164 0.369
strata=LOW 11 3 2.34 0.187 0.369
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5648 1.7592 0.9399 0.601 0.548
Likelihood ratio test=0.37 on 1 df, p=0.5426
n= 22, number of events= 5
============================
TCGA-COAD MAPK3
[1] 264
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 4.59 0.548 1.64
strata=LOW 11 5 3.41 0.737 1.64
Chisq= 1.6 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.9593 2.6098 0.7753 1.237 0.216
Likelihood ratio test=1.54 on 1 df, p=0.2144
n= 22, number of events= 8
============================
TCGA-COAD CYGB
[1] 265
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.04 0.455 0.938
strata=LOW 11 2 2.96 0.313 0.938
Chisq= 0.9 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.0721 0.3423 1.1593 -0.925 0.355
Likelihood ratio test=0.98 on 1 df, p=0.3212
n= 22, number of events= 5
============================
TCGA-COAD MLST8
[1] 266
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.71 0.0222 0.0644
strata=LOW 11 3 3.29 0.0251 0.0644
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2292 0.7952 0.9050 -0.253 0.8
Likelihood ratio test=0.07 on 1 df, p=0.7983
n= 22, number of events= 7
============================
TCGA-COAD PANX2
[1] 267
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.79 0.0153 0.0352
strata=LOW 11 2 2.21 0.0194 0.0352
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1724 0.8416 0.9200 -0.187 0.851
Likelihood ratio test=0.04 on 1 df, p=0.8506
n= 22, number of events= 5
============================
TCGA-COAD PEBP1
[1] 268
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.94 0.000784 0.0018
strata=LOW 11 4 4.06 0.000762 0.0018
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.03251 0.96801 0.76547 -0.042 0.966
Likelihood ratio test=0 on 1 df, p=0.9661
n= 22, number of events= 8
============================
TCGA-COAD PARP8
[1] 269
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 4.14 1.11 2.38
strata=LOW 11 6 3.86 1.19 2.38
Chisq= 2.4 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.218 3.380 0.833 1.462 0.144
Likelihood ratio test=2.49 on 1 df, p=0.1149
n= 22, number of events= 8
============================
TCGA-COAD GJA1
[1] 270
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 1.096 0.746 1.65
strata=LOW 11 0 0.904 0.904 1.65
Chisq= 1.7 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.103e+01 7.382e-10 2.863e+04 -0.001 0.999
Likelihood ratio test=2.41 on 1 df, p=0.1207
n= 22, number of events= 2
============================
TCGA-COAD BAP1
[1] 271
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 1 2.47 0.877 2.31
strata=LOW 11 3 1.53 1.418 2.31
Chisq= 2.3 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.590 4.905 1.158 1.374 0.17
Likelihood ratio test=2.25 on 1 df, p=0.1333
n= 22, number of events= 4
============================
TCGA-COAD MAP3K11
[1] 272
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 5.28 0.0145 0.0438
strata=LOW 11 4 3.72 0.0205 0.0438
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1551 1.1678 0.7421 0.209 0.834
Likelihood ratio test=0.04 on 1 df, p=0.8355
n= 22, number of events= 9
============================
TCGA-COAD TTBK2
[1] 273
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.46 0.681 1.89
strata=LOW 11 1 2.54 0.930 1.89
Chisq= 1.9 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.4197 0.2418 1.1194 -1.268 0.205
Likelihood ratio test=2.02 on 1 df, p=0.155
n= 22, number of events= 6
============================
TCGA-COAD MIR214
============================
TCGA-COAD PARP15
[1] 274
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 4.3 1.23 5.49
strata=LOW 11 4 1.7 3.11 5.49
Chisq= 5.5 on 1 degrees of freedom, p= 0.02
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.159e+01 2.385e+09 2.060e+04 0.001 0.999
Likelihood ratio test=6.93 on 1 df, p=0.008469
n= 22, number of events= 6
============================
TCGA-COAD HDDC3
[1] 275
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 4.12 0.303 0.753
strata=LOW 11 5 3.88 0.322 0.753
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6600 1.9348 0.7735 0.853 0.394
Likelihood ratio test=0.74 on 1 df, p=0.3901
n= 22, number of events= 8
============================
TCGA-COAD MIR10A
============================
TCGA-COAD CGAS
[1] 276
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.68 0.764 2.04
strata=LOW 11 4 2.32 1.209 2.04
Chisq= 2 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.2005 3.3217 0.8856 1.355 0.175
Likelihood ratio test=1.99 on 1 df, p=0.1587
n= 22, number of events= 6
============================
TCGA-COAD SIRT2
[1] 277
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.22 0.0154 0.0336
strata=LOW 11 4 3.78 0.0132 0.0336
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1501 1.1619 0.8195 0.183 0.855
Likelihood ratio test=0.03 on 1 df, p=0.8547
n= 22, number of events= 7
============================
TCGA-COAD PPARD
[1] 278
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.51 0.652 1.59
strata=LOW 11 5 3.49 0.657 1.59
Chisq= 1.6 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.0480 2.8521 0.8694 1.206 0.228
Likelihood ratio test=1.56 on 1 df, p=0.2111
n= 22, number of events= 7
============================
TCGA-COAD EGR1
[1] 279
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.92 0.00211 0.00896
strata=LOW 11 1 1.08 0.00570 0.00896
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1162 0.8903 1.2283 -0.095 0.925
Likelihood ratio test=0.01 on 1 df, p=0.9242
n= 22, number of events= 4
============================
TCGA-COAD AQP3
[1] 280
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.36 0.551 1.27
strata=LOW 11 4 2.64 0.701 1.27
Chisq= 1.3 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.9484 2.5815 0.8720 1.088 0.277
Likelihood ratio test=1.27 on 1 df, p=0.2601
n= 22, number of events= 6
============================
TCGA-COAD HSF1
[1] 281
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 1.72 0.0448 0.107
strata=LOW 11 1 1.28 0.0604 0.107
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4021 0.6689 1.2356 -0.325 0.745
Likelihood ratio test=0.11 on 1 df, p=0.7402
n= 22, number of events= 3
============================
TCGA-COAD MIR18A
============================
TCGA-COAD OSBPL9
[1] 282
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.25 0.0271 0.0463
strata=LOW 11 5 4.75 0.0128 0.0463
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1918 1.2114 0.8927 0.215 0.83
Likelihood ratio test=0.05 on 1 df, p=0.8284
n= 22, number of events= 7
============================
TCGA-COAD SESN2
[1] 283
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.85 0.186 0.416
strata=LOW 11 5 4.15 0.172 0.416
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4901 1.6325 0.7671 0.639 0.523
Likelihood ratio test=0.41 on 1 df, p=0.5201
n= 22, number of events= 8
============================
TCGA-COAD BECN1
[1] 284
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 5.7 0.505 1.23
strata=LOW 11 7 5.3 0.543 1.23
Chisq= 1.2 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7160 2.0462 0.6584 1.088 0.277
Likelihood ratio test=1.21 on 1 df, p=0.271
n= 22, number of events= 11
============================
TCGA-COAD FTMT
============================
TCGA-COAD HCAR1
[1] 285
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 4.65 0.092 0.305
strata=LOW 11 3 2.35 0.182 0.305
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4525 1.5723 0.8253 0.548 0.583
Likelihood ratio test=0.3 on 1 df, p=0.5849
n= 22, number of events= 7
============================
TCGA-COAD HILPDA
[1] 286
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.59 0.0371 0.102
strata=LOW 11 3 3.41 0.0499 0.102
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2494 0.7793 0.7815 -0.319 0.75
Likelihood ratio test=0.1 on 1 df, p=0.7487
n= 22, number of events= 8
============================
TCGA-COAD GSTM1
[1] 287
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.02 0.316 0.644
strata=LOW 11 3 3.98 0.240 0.644
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6855 0.5038 0.8704 -0.788 0.431
Likelihood ratio test=0.66 on 1 df, p=0.4175
n= 22, number of events= 7
============================
TCGA-COAD MIR222
============================
TCGA-COAD RARRES2
[1] 288
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.21 0.0136 0.0314
strata=LOW 11 3 2.79 0.0157 0.0314
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1501 1.1619 0.8470 0.177 0.859
Likelihood ratio test=0.03 on 1 df, p=0.8594
n= 22, number of events= 6
============================
TCGA-COAD BRD4
[1] 289
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 4.22 0.748 2.15
strata=LOW 11 1 2.78 1.138 2.15
Chisq= 2.2 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.4834 0.2269 1.1019 -1.346 0.178
Likelihood ratio test=2.39 on 1 df, p=0.1222
n= 22, number of events= 7
============================
TCGA-COAD SOCS1
[1] 290
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.56 0.0539 0.112
strata=LOW 11 3 3.44 0.0558 0.112
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2571 0.7733 0.7707 -0.334 0.739
Likelihood ratio test=0.11 on 1 df, p=0.7376
n= 22, number of events= 7
============================
TCGA-COAD MIR17
============================
TCGA-COAD GDF15
[1] 291
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.46 0.616 2.37
strata=LOW 11 3 1.54 1.385 2.37
Chisq= 2.4 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.667 5.295 1.190 1.401 0.161
Likelihood ratio test=2.34 on 1 df, p=0.1264
n= 22, number of events= 5
============================
TCGA-COAD ARF6
[1] 292
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 5.15 0.90 2.78
strata=LOW 11 5 2.85 1.63 2.78
Chisq= 2.8 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.3104 3.7076 0.8409 1.558 0.119
Likelihood ratio test=2.75 on 1 df, p=0.09746
n= 22, number of events= 8
============================
TCGA-COAD CDO1
[1] 293
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.94 0.283 0.752
strata=LOW 11 2 3.06 0.365 0.752
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7382 0.4780 0.8702 -0.848 0.396
Likelihood ratio test=0.76 on 1 df, p=0.3819
n= 22, number of events= 7
============================
TCGA-COAD CAMKK2
[1] 294
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.49 0.0757 0.152
strata=LOW 11 3 3.51 0.0751 0.152
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2987 0.7418 0.7677 -0.389 0.697
Likelihood ratio test=0.15 on 1 df, p=0.6957
n= 22, number of events= 7
============================
TCGA-COAD LINC01606
[1] 295
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.62 0.0557 0.0761
strata=LOW 27 8 8.38 0.0174 0.0761
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1911 0.8260 0.6937 -0.276 0.783
Likelihood ratio test=0.07 on 1 df, p=0.7857
n= 38, number of events= 11
============================
TCGA-COAD BACH1
[1] 296
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.47 0.955 1.89
strata=LOW 11 3 4.53 0.519 1.89
Chisq= 1.9 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.4171 0.2424 1.1189 -1.266 0.205
Likelihood ratio test=2.02 on 1 df, p=0.1556
n= 22, number of events= 7
============================
TCGA-COAD DPP4
[1] 297
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 4.01 0.254 0.525
strata=LOW 11 5 3.99 0.255 0.525
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5305 1.6999 0.7402 0.717 0.474
Likelihood ratio test=0.53 on 1 df, p=0.4666
n= 22, number of events= 8
============================
TCGA-COAD PPP1R13L
[1] 298
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.45 0.0688 0.16
strata=LOW 11 4 4.55 0.0672 0.16
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2957 0.7440 0.7422 -0.398 0.69
Likelihood ratio test=0.16 on 1 df, p=0.6873
n= 22, number of events= 9
============================
TCGA-COAD MIR150
============================
TCGA-COAD FLT3
[1] 299
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 1 2.66 1.037 1.88
strata=LOW 11 6 4.34 0.636 1.88
Chisq= 1.9 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.395 4.033 1.098 1.27 0.204
Likelihood ratio test=2.1 on 1 df, p=0.1472
n= 22, number of events= 7
============================
TCGA-COAD MAP1LC3A
[1] 300
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.62 0.725 1.53
strata=LOW 11 2 3.38 0.562 1.53
Chisq= 1.5 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.2940 0.2742 1.1196 -1.156 0.248
Likelihood ratio test=1.65 on 1 df, p=0.1984
n= 22, number of events= 6
============================
TCGA-COAD A2M-AS1
[1] 301
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.14 0.234 0.611
strata=LOW 11 2 2.86 0.258 0.611
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7044 0.4944 0.9194 -0.766 0.444
Likelihood ratio test=0.6 on 1 df, p=0.4376
n= 22, number of events= 6
============================
TCGA-COAD PDSS2
[1] 302
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.1 0.00335 0.00608
strata=LOW 11 4 3.9 0.00266 0.00608
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.0599 1.0617 0.7683 0.078 0.938
Likelihood ratio test=0.01 on 1 df, p=0.9378
n= 22, number of events= 7
============================
TCGA-COAD DNAJB6
[1] 303
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.09 1.75 3.03
strata=LOW 11 1 2.91 1.25 3.03
Chisq= 3 on 1 degrees of freedom, p= 0.08
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.7343 0.1765 1.1220 -1.546 0.122
Likelihood ratio test=3.09 on 1 df, p=0.07876
n= 22, number of events= 5
============================
TCGA-COAD SUV39H1
[1] 304
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.48 0.0781 0.218
strata=LOW 11 2 2.52 0.1077 0.218
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4235 0.6548 0.9140 -0.463 0.643
Likelihood ratio test=0.22 on 1 df, p=0.6396
n= 22, number of events= 6
============================
TCGA-COAD LPCAT3
[1] 305
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.57 0.0729 0.13
strata=LOW 11 5 5.43 0.0344 0.13
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2967 0.7433 0.8255 -0.359 0.719
Likelihood ratio test=0.13 on 1 df, p=0.7197
n= 22, number of events= 8
============================
TCGA-COAD MIR761
============================
TCGA-COAD CDCA3
[1] 306
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.59 0.701 2.05
strata=LOW 11 4 2.41 1.042 2.05
Chisq= 2.1 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.480 4.395 1.126 1.315 0.188
Likelihood ratio test=2.18 on 1 df, p=0.1399
n= 22, number of events= 6
============================
TCGA-COAD EPAS1
[1] 307
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.09 0.203 0.502
strata=LOW 11 3 3.91 0.212 0.502
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5930 0.5526 0.8480 -0.699 0.484
Likelihood ratio test=0.52 on 1 df, p=0.4688
n= 22, number of events= 8
============================
TCGA-COAD SLC11A2
[1] 308
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.76 0.556 1.26
strata=LOW 11 3 4.24 0.362 1.26
Chisq= 1.3 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.1959 0.3024 1.1254 -1.063 0.288
Likelihood ratio test=1.38 on 1 df, p=0.2407
n= 22, number of events= 7
============================
TCGA-COAD CREB3
[1] 309
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.29 0.0260 0.061
strata=LOW 11 3 2.71 0.0317 0.061
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2076 1.2308 0.8419 0.247 0.805
Likelihood ratio test=0.06 on 1 df, p=0.8052
n= 22, number of events= 6
============================
TCGA-COAD ATF3
[1] 310
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.13 0.408 1.11
strata=LOW 11 3 1.87 0.684 1.11
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.9408 2.5619 0.9231 1.019 0.308
Likelihood ratio test=1.07 on 1 df, p=0.3016
n= 22, number of events= 5
============================
TCGA-COAD TGFB1
[1] 311
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.12 1.134 2.1
strata=LOW 11 3 4.88 0.725 2.1
Chisq= 2.1 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.1630 0.3125 0.8452 -1.376 0.169
Likelihood ratio test=2.12 on 1 df, p=0.1453
n= 22, number of events= 8
============================
TCGA-COAD SMG9
[1] 312
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 5.77 0.00953 0.0289
strata=LOW 11 4 4.23 0.01298 0.0289
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1229 0.8843 0.7232 -0.17 0.865
Likelihood ratio test=0.03 on 1 df, p=0.8651
n= 22, number of events= 10
============================
TCGA-COAD NOX4
[1] 313
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.75 0.417 1.06
strata=LOW 11 2 3.25 0.481 1.06
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8693 0.4192 0.8701 -0.999 0.318
Likelihood ratio test=1.07 on 1 df, p=0.3017
n= 22, number of events= 7
============================
TCGA-COAD MIR27A
============================
TCGA-COAD FOXP1
[1] 314
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 4.32 0.654 1.92
strata=LOW 11 1 2.68 1.054 1.92
Chisq= 1.9 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.4046 0.2455 1.0978 -1.28 0.201
Likelihood ratio test=2.14 on 1 df, p=0.1435
n= 22, number of events= 7
============================
TCGA-COAD SNCA
[1] 315
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.43 0.0954 0.264
strata=LOW 11 2 2.57 0.1271 0.264
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4672 0.6268 0.9169 -0.51 0.61
Likelihood ratio test=0.27 on 1 df, p=0.6064
n= 22, number of events= 6
============================
TCGA-COAD ENPP2
[1] 316
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.49 0.1028 0.181
strata=LOW 11 3 3.51 0.0731 0.181
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3507 0.7042 0.8288 -0.423 0.672
Likelihood ratio test=0.18 on 1 df, p=0.6728
n= 22, number of events= 6
============================
TCGA-COAD BRD2
[1] 317
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 1.98 2.069 3.25
strata=LOW 11 3 5.02 0.814 3.25
Chisq= 3.2 on 1 degrees of freedom, p= 0.07
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.4911 0.2251 0.8929 -1.67 0.0949
Likelihood ratio test=3.01 on 1 df, p=0.08259
n= 22, number of events= 7
============================
TCGA-COAD ISCU
[1] 318
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.71 0.0302 0.0665
strata=LOW 11 3 3.29 0.0249 0.0665
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2359 0.7898 0.9166 -0.257 0.797
Likelihood ratio test=0.07 on 1 df, p=0.7956
n= 22, number of events= 6
============================
TCGA-COAD PHF21A
[1] 319
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.68 0.476 1.25
strata=LOW 11 2 3.32 0.527 1.25
Chisq= 1.2 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.9541 0.3851 0.8835 -1.08 0.28
Likelihood ratio test=1.24 on 1 df, p=0.2648
n= 22, number of events= 7
============================
TCGA-COAD PARP6
[1] 320
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.87 0.00617 0.0121
strata=LOW 11 3 3.13 0.00565 0.0121
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.09079 0.91321 0.82603 -0.11 0.912
Likelihood ratio test=0.01 on 1 df, p=0.9125
n= 22, number of events= 6
============================
TCGA-COAD ZEB1
[1] 321
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.44 0.0702 0.252
strata=LOW 11 2 2.56 0.1218 0.252
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4560 0.6338 0.9167 -0.497 0.619
Likelihood ratio test=0.25 on 1 df, p=0.6151
n= 22, number of events= 7
============================
TCGA-COAD LIG3
[1] 322
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 1.44 1.700 2.72
strata=LOW 11 2 3.56 0.686 2.72
Chisq= 2.7 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.7154 0.1799 1.1646 -1.473 0.141
Likelihood ratio test=2.59 on 1 df, p=0.1072
n= 22, number of events= 5
============================
TCGA-COAD PEDS1
[1] 323
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.32 0.109 0.317
strata=LOW 11 2 2.68 0.175 0.317
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4838 0.6164 0.8675 -0.558 0.577
Likelihood ratio test=0.33 on 1 df, p=0.5684
n= 22, number of events= 7
============================
TCGA-COAD RPPH1
============================
TCGA-COAD GFRA1
[1] 324
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.09 1.74 3.04
strata=LOW 11 1 2.91 1.25 3.04
Chisq= 3 on 1 degrees of freedom, p= 0.08
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.737 0.176 1.123 -1.547 0.122
Likelihood ratio test=3.09 on 1 df, p=0.0786
n= 22, number of events= 5
============================
TCGA-COAD AQP8
[1] 325
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.98 0.983 2.29
strata=LOW 11 6 4.02 0.973 2.29
Chisq= 2.3 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.1992 3.3175 0.8392 1.429 0.153
Likelihood ratio test=2.3 on 1 df, p=0.1293
n= 22, number of events= 8
============================
TCGA-COAD SIRT1
[1] 326
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 1.53 0.1448 0.296
strata=LOW 11 2 2.47 0.0896 0.296
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6544 0.5198 1.2252 -0.534 0.593
Likelihood ratio test=0.3 on 1 df, p=0.5827
n= 22, number of events= 4
============================
TCGA-COAD MIR15A
============================
TCGA-COAD AKR1C3
[1] 327
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.29 0.0256 0.0594
strata=LOW 11 4 3.71 0.0227 0.0594
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2032 1.2253 0.8351 0.243 0.808
Likelihood ratio test=0.06 on 1 df, p=0.808
n= 22, number of events= 7
============================
TCGA-COAD DLD
[1] 328
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.86 0.257 0.492
strata=LOW 11 5 4.14 0.177 0.492
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5992 1.8207 0.8671 0.691 0.49
Likelihood ratio test=0.5 on 1 df, p=0.4779
n= 22, number of events= 7
============================
TCGA-COAD USP11
[1] 329
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.05 1.85 3.2
strata=LOW 11 1 2.95 1.29 3.2
Chisq= 3.2 on 1 degrees of freedom, p= 0.07
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.7775 0.1691 1.1240 -1.581 0.114
Likelihood ratio test=3.24 on 1 df, p=0.07199
n= 22, number of events= 5
============================
TCGA-COAD SREBF2
[1] 330
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.83 0.355 0.791
strata=LOW 11 2 3.17 0.429 0.791
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7311 0.4814 0.8400 -0.87 0.384
Likelihood ratio test=0.83 on 1 df, p=0.3637
n= 22, number of events= 7
============================
TCGA-COAD MIR190A
============================
TCGA-COAD IFNA8
============================
TCGA-COAD KDM6B
[1] 331
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.8 0.510 0.997
strata=LOW 11 2 3.2 0.447 0.997
Chisq= 1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.8627 0.4220 0.8874 -0.972 0.331
Likelihood ratio test=1.01 on 1 df, p=0.3147
n= 22, number of events= 6
============================
TCGA-COAD ACOT1
[1] 332
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.57 0.0513 0.147
strata=LOW 11 2 2.43 0.0755 0.147
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3484 0.7058 0.9134 -0.381 0.703
Likelihood ratio test=0.15 on 1 df, p=0.7002
n= 22, number of events= 6
============================
TCGA-COAD RELA
[1] 333
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.2 0.202 0.378
strata=LOW 11 4 4.8 0.134 0.378
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4702 0.6249 0.7711 -0.61 0.542
Likelihood ratio test=0.38 on 1 df, p=0.5393
n= 22, number of events= 8
============================
TCGA-COAD SLC39A7
[1] 334
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.44 0.0570 0.135
strata=LOW 11 3 2.56 0.0767 0.135
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3008 1.3510 0.8213 0.366 0.714
Likelihood ratio test=0.13 on 1 df, p=0.7146
n= 22, number of events= 6
============================
TCGA-COAD POM121L12
============================
TCGA-COAD MIR101-1
============================
TCGA-COAD GABPB1-AS1
[1] 335
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.41 0.0486 0.116
strata=LOW 11 4 3.59 0.0461 0.116
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2951 1.3433 0.8699 0.339 0.734
Likelihood ratio test=0.12 on 1 df, p=0.7307
n= 22, number of events= 7
============================
TCGA-COAD EGFR
[1] 336
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.19 0.203 0.438
strata=LOW 11 2 2.81 0.231 0.438
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5678 0.5668 0.8691 -0.653 0.514
Likelihood ratio test=0.45 on 1 df, p=0.5028
n= 22, number of events= 6
============================
TCGA-COAD BRD7
[1] 337
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.45 0.126 0.249
strata=LOW 11 2 2.55 0.120 0.249
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4542 0.6349 0.9181 -0.495 0.621
Likelihood ratio test=0.25 on 1 df, p=0.617
n= 22, number of events= 5
============================
TCGA-COAD MIR1287
============================
TCGA-COAD MIR23A
============================
TCGA-COAD LCE2C
============================
TCGA-COAD ADAMTS13
[1] 338
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 1.62 0.0909 0.159
strata=LOW 11 2 2.38 0.0617 0.159
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4045 0.6673 1.0219 -0.396 0.692
Likelihood ratio test=0.16 on 1 df, p=0.6929
n= 22, number of events= 4
============================
TCGA-COAD SIRT3
[1] 339
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.47 0.1153 0.228
strata=LOW 11 3 3.53 0.0805 0.228
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4324 0.6489 0.9132 -0.474 0.636
Likelihood ratio test=0.23 on 1 df, p=0.6322
n= 22, number of events= 6
============================
TCGA-COAD CIRBP
[1] 340
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.31 0.208 0.39
strata=LOW 11 3 3.69 0.130 0.39
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5650 0.5684 0.9169 -0.616 0.538
Likelihood ratio test=0.39 on 1 df, p=0.5327
n= 22, number of events= 6
============================
TCGA-COAD BRDT
============================
TCGA-COAD KIF4A
[1] 341
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.01 2.25e-05 4.52e-05
strata=LOW 11 3 2.99 2.26e-05 4.52e-05
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.005498 1.005513 0.817625 0.007 0.995
Likelihood ratio test=0 on 1 df, p=0.9946
n= 22, number of events= 6
============================
TCGA-COAD CPEB1
[1] 342
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 4.93 0.231 0.767
strata=LOW 11 2 3.07 0.371 0.767
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7449 0.4748 0.8700 -0.856 0.392
Likelihood ratio test=0.78 on 1 df, p=0.3774
n= 22, number of events= 8
============================
TCGA-COAD LINC01833
[1] 343
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 1.88 0.00793 0.0131
strata=LOW 14 3 3.12 0.00477 0.0131
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1058 0.8996 0.9261 -0.114 0.909
Likelihood ratio test=0.01 on 1 df, p=0.9094
n= 25, number of events= 5
============================
TCGA-COAD MAPKAP1
[1] 344
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 1.97 0.541 1.07
strata=LOW 11 1 2.03 0.524 1.07
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.1385 0.3203 1.1581 -0.983 0.326
Likelihood ratio test=1.12 on 1 df, p=0.2901
n= 22, number of events= 4
============================
TCGA-COAD ATF4
[1] 345
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.83 0.01051 0.02
strata=LOW 11 3 3.17 0.00937 0.02
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1155 0.8909 0.8180 -0.141 0.888
Likelihood ratio test=0.02 on 1 df, p=0.8878
n= 22, number of events= 6
============================
TCGA-COAD SLC7A11
[1] 346
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.33 0.104 0.259
strata=LOW 11 3 3.67 0.122 0.259
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3871 0.6790 0.7657 -0.506 0.613
Likelihood ratio test=0.26 on 1 df, p=0.611
n= 22, number of events= 8
============================
TCGA-COAD EMC2
[1] 347
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.46 0.0852 0.168
strata=LOW 11 4 3.54 0.0591 0.168
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3725 1.4513 0.9140 0.408 0.684
Likelihood ratio test=0.17 on 1 df, p=0.6807
n= 22, number of events= 6
============================
TCGA-COAD WWTR1
[1] 348
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.39 0.0859 0.303
strata=LOW 11 2 2.61 0.1441 0.303
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4989 0.6072 0.9150 -0.545 0.586
Likelihood ratio test=0.3 on 1 df, p=0.5812
n= 22, number of events= 7
============================
TCGA-COAD HSPA5
[1] 349
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.14 0.236 0.606
strata=LOW 11 2 2.86 0.259 0.606
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6977 0.4978 0.9141 -0.763 0.445
Likelihood ratio test=0.6 on 1 df, p=0.4393
n= 22, number of events= 6
============================
TCGA-COAD BEX1
[1] 350
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.47 0.0634 0.163
strata=LOW 11 3 3.53 0.0802 0.163
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3084 0.7346 0.7667 -0.402 0.687
Likelihood ratio test=0.16 on 1 df, p=0.6859
n= 22, number of events= 8
============================
TCGA-COAD PML
[1] 351
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 2.69 4.07 6.75
strata=LOW 11 1 4.31 2.54 6.75
Chisq= 6.8 on 1 degrees of freedom, p= 0.009
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.30627 0.09963 1.08628 -2.123 0.0337
Likelihood ratio test=6.85 on 1 df, p=0.008882
n= 22, number of events= 7
============================
TCGA-COAD MIR142
============================
TCGA-COAD AEBP2
[1] 352
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 1.31 2.17 3.89
strata=LOW 11 1 2.69 1.06 3.89
Chisq= 3.9 on 1 degrees of freedom, p= 0.05
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.151e+01 4.565e-10 2.360e+04 -0.001 0.999
Likelihood ratio test=4.99 on 1 df, p=0.02547
n= 22, number of events= 4
============================
TCGA-COAD GPAT4
[1] 353
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.01 0.245 0.82
strata=LOW 11 1 1.99 0.493 0.82
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.9743 0.3775 1.1187 -0.871 0.384
Likelihood ratio test=0.9 on 1 df, p=0.3426
n= 22, number of events= 6
============================
TCGA-COAD CA9
[1] 354
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 2.76 1.83 3.39
strata=LOW 11 1 3.24 1.55 3.39
Chisq= 3.4 on 1 degrees of freedom, p= 0.07
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.7801 0.1686 1.0971 -1.622 0.105
Likelihood ratio test=3.62 on 1 df, p=0.05713
n= 22, number of events= 6
============================
TCGA-COAD STK11
[1] 355
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 5.72 0.0133 0.0373
strata=LOW 11 3 3.28 0.0232 0.0373
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1381 0.8710 0.7155 -0.193 0.847
Likelihood ratio test=0.04 on 1 df, p=0.8459
n= 22, number of events= 9
============================
TCGA-COAD TBK1
[1] 356
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2 8.70e-06 1.76e-05
strata=LOW 11 3 3 5.78e-06 1.76e-05
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.00423 0.99578 1.00760 -0.004 0.997
Likelihood ratio test=0 on 1 df, p=0.9967
n= 22, number of events= 5
============================
TCGA-COAD CDKN2A
[1] 357
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 1 1.34 0.0861 0.156
strata=LOW 11 2 1.66 0.0695 0.156
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.479 1.615 1.225 0.391 0.696
Likelihood ratio test=0.16 on 1 df, p=0.6893
n= 22, number of events= 3
============================
TCGA-COAD DCAF7
[1] 358
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.5 0.1 0.281
strata=LOW 11 2 2.5 0.1 0.281
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5394 0.5831 1.0291 -0.524 0.6
Likelihood ratio test=0.27 on 1 df, p=0.6016
n= 22, number of events= 5
============================
TCGA-COAD MTF1
[1] 359
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.1 0.00353 0.0111
strata=LOW 11 2 1.9 0.00579 0.0111
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1061 1.1119 1.0059 0.105 0.916
Likelihood ratio test=0.01 on 1 df, p=0.916
n= 22, number of events= 5
============================
TCGA-COAD MEG8
[1] 360
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.93 0.291 0.635
strata=LOW 11 4 5.07 0.225 0.635
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5667 0.5674 0.7197 -0.787 0.431
Likelihood ratio test=0.61 on 1 df, p=0.4337
n= 22, number of events= 9
============================
TCGA-COAD CLTRN
[1] 361
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 1.83 0.01563 0.0249
strata=LOW 11 4 4.17 0.00687 0.0249
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1448 0.8652 0.9178 -0.158 0.875
Likelihood ratio test=0.02 on 1 df, p=0.8753
n= 22, number of events= 6
============================
TCGA-COAD PARP11
[1] 362
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 3.94 1.082 2
strata=LOW 11 3 5.06 0.841 2
Chisq= 2 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.9798 0.3754 0.7178 -1.365 0.172
Likelihood ratio test=1.99 on 1 df, p=0.1582
n= 22, number of events= 9
============================
TCGA-COAD GABARAPL2
[1] 363
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.04 0.354 0.717
strata=LOW 11 5 3.96 0.271 0.717
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.7186 2.0515 0.8667 0.829 0.407
Likelihood ratio test=0.73 on 1 df, p=0.3928
n= 22, number of events= 7
============================
TCGA-COAD CDKN1A
[1] 364
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.89 0.922 2.19
strata=LOW 11 6 4.11 0.874 2.19
Chisq= 2.2 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.1985 3.3151 0.8526 1.406 0.16
Likelihood ratio test=2.21 on 1 df, p=0.1375
n= 22, number of events= 8
============================
TCGA-COAD NEDD4L
[1] 365
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 2.68 0.174 0.327
strata=LOW 11 4 3.32 0.141 0.327
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4985 1.6463 0.8797 0.567 0.571
Likelihood ratio test=0.34 on 1 df, p=0.5627
n= 22, number of events= 6
============================
TCGA-COAD AR
[1] 366
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.24 0.96 2.53
strata=LOW 11 1 2.76 1.12 2.53
Chisq= 2.5 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.6061 0.2007 1.1203 -1.434 0.152
Likelihood ratio test=2.63 on 1 df, p=0.1048
n= 22, number of events= 6
============================
TCGA-COAD MIR20A
============================
TCGA-COAD HMOX1
[1] 367
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 4.43 0.460 1.3
strata=LOW 11 6 4.57 0.445 1.3
Chisq= 1.3 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8621 2.3682 0.7781 1.108 0.268
Likelihood ratio test=1.24 on 1 df, p=0.2654
n= 22, number of events= 9
============================
TCGA-COAD ZFP36
[1] 368
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.13 0.356 0.806
strata=LOW 11 1 1.87 0.405 0.806
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.0266 0.3582 1.1856 -0.866 0.387
Likelihood ratio test=0.85 on 1 df, p=0.3558
n= 22, number of events= 4
============================
TCGA-COAD MIR744
============================
TCGA-COAD CTSB
[1] 369
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.3 0.147 0.279
strata=LOW 11 4 4.7 0.103 0.279
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4011 0.6696 0.7644 -0.525 0.6
Likelihood ratio test=0.28 on 1 df, p=0.5975
n= 22, number of events= 8
============================
TCGA-COAD AGPS
[1] 370
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.78 0.540 0.902
strata=LOW 11 3 4.22 0.355 0.902
Chisq= 0.9 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7135 0.4899 0.7670 -0.93 0.352
Likelihood ratio test=0.88 on 1 df, p=0.3491
n= 22, number of events= 7
============================
TCGA-COAD MT1DP
[1] 371
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 6.12 0.205 0.537
strata=LOW 11 6 4.88 0.257 0.537
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.4635 1.5896 0.6380 0.727 0.468
Likelihood ratio test=0.52 on 1 df, p=0.4694
n= 22, number of events= 11
============================
TCGA-COAD SNX4
[1] 372
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.51 0.651 1.31
strata=LOW 11 6 4.49 0.509 1.31
Chisq= 1.3 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.9248 2.5214 0.8373 1.105 0.269
Likelihood ratio test=1.35 on 1 df, p=0.245
n= 22, number of events= 8
============================
TCGA-COAD NR4A1
[1] 373
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.17 0.00890 0.0189
strata=LOW 11 3 2.83 0.00995 0.0189
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1126 1.1192 0.8186 0.138 0.891
Likelihood ratio test=0.02 on 1 df, p=0.8906
n= 22, number of events= 6
============================
TCGA-COAD MFN2
[1] 374
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 7 5.64 0.326 0.828
strata=LOW 11 3 4.36 0.423 0.828
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6365 0.5291 0.7108 -0.895 0.371
Likelihood ratio test=0.85 on 1 df, p=0.3574
n= 22, number of events= 10
============================
TCGA-COAD SELENOI
[1] 375
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.67 0.0404 0.147
strata=LOW 11 1 1.33 0.0813 0.147
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4668 0.6270 1.2288 -0.38 0.704
Likelihood ratio test=0.15 on 1 df, p=0.6978
n= 22, number of events= 4
============================
TCGA-COAD AGAP2-AS1
[1] 376
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.72 0.439 1.41
strata=LOW 11 1 2.28 0.718 1.41
Chisq= 1.4 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.2689 0.2811 1.1348 -1.118 0.263
Likelihood ratio test=1.52 on 1 df, p=0.2181
n= 22, number of events= 6
============================
TCGA-COAD TRIM46
[1] 377
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.53 0.0489 0.12
strata=LOW 11 4 4.47 0.0496 0.12
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2529 0.7765 0.7303 -0.346 0.729
Likelihood ratio test=0.12 on 1 df, p=0.7297
n= 22, number of events= 9
============================
TCGA-COAD CYB5R1
[1] 378
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.41 0.143 0.279
strata=LOW 11 2 2.59 0.133 0.279
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4791 0.6193 0.9161 -0.523 0.601
Likelihood ratio test=0.28 on 1 df, p=0.5969
n= 22, number of events= 5
============================
TCGA-COAD PARK7
[1] 379
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.3 0.211 0.392
strata=LOW 11 2 2.7 0.180 0.392
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5646 0.5686 0.9140 -0.618 0.537
Likelihood ratio test=0.39 on 1 df, p=0.5317
n= 22, number of events= 5
============================
TCGA-COAD CARS1
[1] 380
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.64 0.698 1.93
strata=LOW 11 1 2.36 0.782 1.93
Chisq= 1.9 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.4772 0.2283 1.1596 -1.274 0.203
Likelihood ratio test=1.92 on 1 df, p=0.1654
n= 22, number of events= 5
============================
TCGA-COAD NOX1
[1] 381
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 4.55 0.0669 0.221
strata=LOW 11 3 2.45 0.1243 0.221
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3926 1.4809 0.8402 0.467 0.64
Likelihood ratio test=0.22 on 1 df, p=0.6409
n= 22, number of events= 7
============================
TCGA-COAD VDR
[1] 382
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 4.62 0.0831 0.199
strata=LOW 11 4 3.38 0.1135 0.199
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3165 1.3722 0.7119 0.445 0.657
Likelihood ratio test=0.2 on 1 df, p=0.6573
n= 22, number of events= 8
============================
TCGA-COAD PROK2
[1] 383
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.15 0.232 0.515
strata=LOW 11 3 3.85 0.190 0.515
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6294 0.5329 0.8891 -0.708 0.479
Likelihood ratio test=0.53 on 1 df, p=0.4675
n= 22, number of events= 7
============================
TCGA-COAD FABP4
[1] 384
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.3 0.148 0.4
strata=LOW 11 2 2.7 0.181 0.4
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5750 0.5627 0.9206 -0.625 0.532
Likelihood ratio test=0.4 on 1 df, p=0.5273
n= 22, number of events= 6
============================
TCGA-COAD ABCB10
[1] 385
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 1.81 0.02054 0.038
strata=LOW 11 4 4.19 0.00885 0.038
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1958 0.8222 1.0065 -0.195 0.846
Likelihood ratio test=0.04 on 1 df, p=0.8459
n= 22, number of events= 6
============================
TCGA-COAD CP
[1] 386
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.48 0.669 1.62
strata=LOW 11 2 3.52 0.660 1.62
Chisq= 1.6 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.0579 0.3472 0.8702 -1.216 0.224
Likelihood ratio test=1.59 on 1 df, p=0.2073
n= 22, number of events= 7
============================
TCGA-COAD MIR4735
============================
TCGA-COAD MIR130A
============================
TCGA-COAD TUG1
[1] 387
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 3.2 1.01 2.65
strata=LOW 11 1 2.8 1.16 2.65
Chisq= 2.6 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.6373 0.1945 1.1203 -1.462 0.144
Likelihood ratio test=2.74 on 1 df, p=0.09771
n= 22, number of events= 6
============================
TCGA-COAD MIR9-3HG
[1] 388
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.04 0.000433 0.000768
strata=LOW 11 5 4.96 0.000265 0.000768
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.02121 1.02144 0.76564 0.028 0.978
Likelihood ratio test=0 on 1 df, p=0.9779
n= 22, number of events= 8
============================
TCGA-COAD MIR196C
============================
TCGA-COAD IFNA21
============================
TCGA-COAD RP11-274B21.9
[1] 389
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.32 0.1401 0.245
strata=LOW 11 4 4.68 0.0993 0.245
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3520 0.7033 0.7152 -0.492 0.623
Likelihood ratio test=0.24 on 1 df, p=0.6234
n= 22, number of events= 8
============================
TCGA-COAD PVT1
[1] 390
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 4.97 0.190 0.808
strata=LOW 11 3 2.03 0.465 0.808
Chisq= 0.8 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8147 2.2584 0.9293 0.877 0.381
Likelihood ratio test=0.79 on 1 df, p=0.374
n= 22, number of events= 7
============================
TCGA-COAD MIR539
============================
TCGA-COAD IFNA2
============================
TCGA-COAD TFRC
[1] 391
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.37 0.166 0.326
strata=LOW 11 3 3.63 0.108 0.326
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5240 0.5922 0.9277 -0.565 0.572
Likelihood ratio test=0.33 on 1 df, p=0.5678
n= 22, number of events= 6
============================
TCGA-COAD ALOX15B
[1] 392
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 1 2.67 1.043 1.98
strata=LOW 11 6 4.33 0.642 1.98
Chisq= 2 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.454 4.280 1.116 1.303 0.193
Likelihood ratio test=2.2 on 1 df, p=0.1378
n= 22, number of events= 7
============================
TCGA-COAD MPC1
[1] 393
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 3.8 0.855 2.4
strata=LOW 11 4 2.2 1.480 2.4
Chisq= 2.4 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.2752 3.5793 0.8759 1.456 0.145
Likelihood ratio test=2.28 on 1 df, p=0.1307
n= 22, number of events= 6
============================
TCGA-COAD MTCH1
[1] 394
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.17 0.218 0.465
strata=LOW 11 3 3.83 0.180 0.465
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5840 0.5576 0.8684 -0.673 0.501
Likelihood ratio test=0.48 on 1 df, p=0.4901
n= 22, number of events= 7
============================
TCGA-COAD MIR324
============================
TCGA-COAD SNHG14
[1] 395
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 4.09 0.890 2.22
strata=LOW 11 2 3.91 0.932 2.22
Chisq= 2.2 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.1995 0.3013 0.8501 -1.411 0.158
Likelihood ratio test=2.22 on 1 df, p=0.1358
n= 22, number of events= 8
============================
TCGA-COAD PDK4
[1] 396
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 1.28 0.402 0.612
strata=LOW 11 3 3.72 0.139 0.612
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7804 0.4582 1.0202 -0.765 0.444
Likelihood ratio test=0.57 on 1 df, p=0.4493
n= 22, number of events= 5
============================
TCGA-COAD DUOX1
[1] 397
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.64 0.0283 0.0678
strata=LOW 11 4 4.36 0.0301 0.0678
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1862 0.8301 0.7161 -0.26 0.795
Likelihood ratio test=0.07 on 1 df, p=0.795
n= 22, number of events= 9
============================
TCGA-COAD LINC00886
[1] 398
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 1 2.82 1.18 2.23
strata=LOW 11 5 3.18 1.05 2.23
Chisq= 2.2 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.494 4.454 1.096 1.363 0.173
Likelihood ratio test=2.46 on 1 df, p=0.1166
n= 22, number of events= 6
============================
TCGA-COAD NF2
[1] 399
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 8 5.91 0.742 2.35
strata=LOW 11 1 3.09 1.417 2.35
Chisq= 2.4 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.5039 0.2223 1.0733 -1.401 0.161
Likelihood ratio test=2.76 on 1 df, p=0.09684
n= 22, number of events= 9
============================
TCGA-COAD MIR149
============================
TCGA-COAD CYP4F8
[1] 400
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 5 1.88e-06 4.26e-06
strata=LOW 11 4 4 2.35e-06 4.26e-06
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.001389 0.998612 0.673190 -0.002 0.998
Likelihood ratio test=0 on 1 df, p=0.9984
n= 22, number of events= 9
============================
TCGA-COAD AKR1C1
[1] 401
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.2 0.200 0.529
strata=LOW 11 2 2.8 0.229 0.529
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.6587 0.5175 0.9209 -0.715 0.474
Likelihood ratio test=0.53 on 1 df, p=0.4687
n= 22, number of events= 6
============================
TCGA-COAD PRKCA
[1] 402
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 1.94 2.18 3.72
strata=LOW 11 1 3.06 1.38 3.72
Chisq= 3.7 on 1 degrees of freedom, p= 0.05
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.9272 0.1455 1.1391 -1.692 0.0907
Likelihood ratio test=3.72 on 1 df, p=0.05392
n= 22, number of events= 5
============================
TCGA-COAD CD44
[1] 403
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.72 0.0215 0.054
strata=LOW 11 3 3.28 0.0243 0.054
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1900 0.8270 0.8186 -0.232 0.816
Likelihood ratio test=0.05 on 1 df, p=0.8166
n= 22, number of events= 7
============================
TCGA-COAD FBXW7
[1] 404
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.93 0.00160 0.00279
strata=LOW 11 4 4.07 0.00115 0.00279
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.04058 0.96023 0.76876 -0.053 0.958
Likelihood ratio test=0 on 1 df, p=0.9579
n= 22, number of events= 7
============================
TCGA-COAD YAP1
[1] 405
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.32 0.139 0.375
strata=LOW 11 2 2.68 0.172 0.375
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5553 0.5739 0.9183 -0.605 0.545
Likelihood ratio test=0.37 on 1 df, p=0.5406
n= 22, number of events= 6
============================
TCGA-COAD MTOR
[1] 406
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.27 0.235 0.732
strata=LOW 11 1 1.73 0.308 0.732
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.008 0.365 1.228 -0.821 0.412
Likelihood ratio test=0.72 on 1 df, p=0.3945
n= 22, number of events= 4
============================
TCGA-COAD RICTOR
[1] 407
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.62 0.0408 0.103
strata=LOW 11 3 3.38 0.0436 0.103
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2664 0.7661 0.8313 -0.321 0.749
Likelihood ratio test=0.1 on 1 df, p=0.7488
n= 22, number of events= 7
============================
TCGA-COAD WIPI2
[1] 408
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.57 0.799 1.64
strata=LOW 11 2 3.43 0.598 1.64
Chisq= 1.6 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.3333 0.2636 1.1184 -1.192 0.233
Likelihood ratio test=1.77 on 1 df, p=0.1834
n= 22, number of events= 6
============================
TCGA-COAD IREB2
[1] 409
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.97 0.000234 0.000408
strata=LOW 11 5 5.03 0.000138 0.000408
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.01545 0.98467 0.76516 -0.02 0.984
Likelihood ratio test=0 on 1 df, p=0.9839
n= 22, number of events= 8
============================
TCGA-COAD GOT1
[1] 410
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 4.08 0.284 0.691
strata=LOW 11 4 2.92 0.396 0.691
Chisq= 0.7 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.6303 1.8782 0.7704 0.818 0.413
Likelihood ratio test=0.68 on 1 df, p=0.41
n= 22, number of events= 7
============================
TCGA-COAD CD82
[1] 411
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 0.967 1.10 2.14
strata=LOW 11 0 1.033 1.03 2.14
Chisq= 2.1 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.127e+01 5.763e-10 2.846e+04 -0.001 0.999
Likelihood ratio test=2.91 on 1 df, p=0.088
n= 22, number of events= 2
============================
TCGA-COAD MAPK9
[1] 412
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.25 0.2476 0.369
strata=LOW 11 5 5.75 0.0971 0.369
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4621 0.6300 0.7678 -0.602 0.547
Likelihood ratio test=0.35 on 1 df, p=0.5532
n= 22, number of events= 8
============================
TCGA-COAD LGMN
[1] 413
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 1 1.75 0.324 0.588
strata=LOW 11 4 3.25 0.175 0.588
Chisq= 0.6 on 1 degrees of freedom, p= 0.4
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8639 2.3724 1.1612 0.744 0.457
Likelihood ratio test=0.62 on 1 df, p=0.4299
n= 22, number of events= 5
============================
TCGA-COAD PARP2
[1] 414
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.28 0.228 0.371
strata=LOW 11 3 3.72 0.140 0.371
Chisq= 0.4 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.4951 0.6095 0.8205 -0.603 0.546
Likelihood ratio test=0.36 on 1 df, p=0.5482
n= 22, number of events= 6
============================
TCGA-COAD MIR16-1
============================
TCGA-COAD ATG4D
[1] 415
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 5.05 0.835 3.39
strata=LOW 11 4 1.95 2.171 3.39
Chisq= 3.4 on 1 degrees of freedom, p= 0.07
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 1.5103 4.5283 0.8871 1.702 0.0887
Likelihood ratio test=3.11 on 1 df, p=0.07759
n= 22, number of events= 7
============================
TCGA-COAD RBMS1
[1] 416
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 3.84 1.217 2.6
strata=LOW 11 3 5.16 0.905 2.6
Chisq= 2.6 on 1 degrees of freedom, p= 0.1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.1306 0.3228 0.7369 -1.534 0.125
Likelihood ratio test=2.45 on 1 df, p=0.1173
n= 22, number of events= 9
============================
TCGA-COAD GSTZ1
[1] 417
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.94 0.001172 0.00234
strata=LOW 11 4 4.06 0.000849 0.00234
Chisq= 0 on 1 degrees of freedom, p= 1
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.03989 0.96089 0.82424 -0.048 0.961
Likelihood ratio test=0 on 1 df, p=0.9614
n= 22, number of events= 7
============================
TCGA-COAD SRSF9
[1] 418
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 3.53 0.0635 0.131
strata=LOW 11 4 4.47 0.0500 0.131
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2786 0.7569 0.7727 -0.361 0.718
Likelihood ratio test=0.13 on 1 df, p=0.7171
n= 22, number of events= 8
============================
TCGA-COAD HIF1A
[1] 419
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 2.68 0.648 1.07
strata=LOW 11 3 4.32 0.402 1.07
Chisq= 1.1 on 1 degrees of freedom, p= 0.3
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.7796 0.4586 0.7719 -1.01 0.312
Likelihood ratio test=1.03 on 1 df, p=0.3094
n= 22, number of events= 7
============================
TCGA-COAD FNDC3B
[1] 420
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 4.26 0.0162 0.041
strata=LOW 11 4 3.74 0.0185 0.041
Chisq= 0 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.1570 1.1700 0.7762 0.202 0.84
Likelihood ratio test=0.04 on 1 df, p=0.8392
n= 22, number of events= 8
============================
TCGA-COAD RHEBP1
============================
TCGA-COAD PSEN1
[1] 421
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 4.63 0.0858 0.211
strata=LOW 11 5 4.37 0.0909 0.211
Chisq= 0.2 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3293 1.3901 0.7199 0.458 0.647
Likelihood ratio test=0.21 on 1 df, p=0.648
n= 22, number of events= 9
============================
TCGA-COAD ADIPOQ
[1] 422
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 5.46 0.393 1.37
strata=LOW 11 4 2.54 0.846 1.37
Chisq= 1.4 on 1 degrees of freedom, p= 0.2
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.8804 2.4118 0.7759 1.135 0.257
Likelihood ratio test=1.3 on 1 df, p=0.254
n= 22, number of events= 8
============================
TCGA-COAD MUC1
[1] 423
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 5.43 0.0335 0.097
strata=LOW 11 4 3.57 0.0509 0.097
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.226 1.254 0.727 0.311 0.756
Likelihood ratio test=0.1 on 1 df, p=0.756
n= 22, number of events= 9
============================
TCGA-COAD CAV1
[1] 424
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.62 0.0320 0.12
strata=LOW 11 2 2.38 0.0619 0.12
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3164 0.7288 0.9181 -0.345 0.73
Likelihood ratio test=0.12 on 1 df, p=0.7282
n= 22, number of events= 7
============================
TCGA-COAD SEC24B
[1] 425
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.29 0.119 0.272
strata=LOW 11 4 4.71 0.108 0.272
Chisq= 0.3 on 1 degrees of freedom, p= 0.6
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3727 0.6889 0.7191 -0.518 0.604
Likelihood ratio test=0.27 on 1 df, p=0.6049
n= 22, number of events= 9
============================
TCGA-COAD PRDX6
[1] 426
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.96 0.232 0.472
strata=LOW 11 5 4.04 0.228 0.472
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.5027 1.6532 0.7388 0.68 0.496
Likelihood ratio test=0.48 on 1 df, p=0.4897
n= 22, number of events= 8
============================
TCGA-COAD TMEM161B-DT
[1] 427
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 3.37 0.0398 0.112
strata=LOW 11 3 2.63 0.0508 0.112
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.3108 1.3645 0.9326 0.333 0.739
Likelihood ratio test=0.11 on 1 df, p=0.7368
n= 22, number of events= 6
============================
TCGA-COAD PGD
[1] 428
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 4 4.42 0.0392 0.119
strata=LOW 11 3 2.58 0.0669 0.119
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 0.2815 1.3252 0.8203 0.343 0.731
Likelihood ratio test=0.12 on 1 df, p=0.7318
n= 22, number of events= 7
============================
TCGA-COAD RHOT1
[1] 429
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 1.74 0.0389 0.0691
strata=LOW 11 2 2.26 0.0300 0.0691
Chisq= 0.1 on 1 degrees of freedom, p= 0.8
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2625 0.7691 1.0014 -0.262 0.793
Likelihood ratio test=0.07 on 1 df, p=0.7935
n= 22, number of events= 4
============================
TCGA-COAD ACSL1
[1] 430
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.55 0.0451 0.121
strata=LOW 11 3 3.45 0.0594 0.121
Chisq= 0.1 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.2691 0.7641 0.7751 -0.347 0.729
Likelihood ratio test=0.12 on 1 df, p=0.7274
n= 22, number of events= 8
============================
TCGA-COAD NEDD4
[1] 431
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.47 0.1137 0.195
strata=LOW 11 3 3.53 0.0795 0.195
Chisq= 0.2 on 1 degrees of freedom, p= 0.7
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.3613 0.6968 0.8214 -0.44 0.66
Likelihood ratio test=0.19 on 1 df, p=0.6609
n= 22, number of events= 6
============================
TCGA-COAD ELOVL5
[1] 432
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 4.06 0.219 0.523
strata=LOW 11 3 3.94 0.226 0.523
Chisq= 0.5 on 1 degrees of freedom, p= 0.5
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.5487 0.5777 0.7682 -0.714 0.475
Likelihood ratio test=0.52 on 1 df, p=0.4721
n= 22, number of events= 8
============================
TCGA-COAD YY1AP1
[1] 433
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 2.79 0.0153 0.0288
strata=LOW 11 3 3.21 0.0134 0.0288
Chisq= 0 on 1 degrees of freedom, p= 0.9
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -0.1386 0.8706 0.8176 -0.169 0.865
Likelihood ratio test=0.03 on 1 df, p=0.8655
n= 22, number of events= 6
============================
Display the results only for genes where a significant difference in survival has been reported.
significant_genes [1] "PANX1" "CCDC6" "LINC00551" "MIB1" "PIK3CA" "GALNT14" "MEF2C" "PARP15" "PML" "AEBP2" num_significant_genes <- length(significant_genes)
if (num_significant_genes > 0) {
for (i in 1 : num_significant_genes) {
project <- significant_projects[[i]]
gene <- significant_genes[[i]]
cat(project, gene, "\n\n")
gene_df <- construct_gene_df(gene, project)
fit <- compute_surival_fit(gene_df)
survival <- compute_survival_diff(gene_df)
cox <- compute_cox(gene_df)
print(survival)
cat("\n")
print(cox)
print(plot_survival(fit))
cat("\n\n============================\n\n")
}
}TCGA-COAD PANX1 Warning: Loglik converged before variable 1 ; coefficient may be infinite. Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 3.32 2.16 5.79
strata=LOW 11 0 2.68 2.68 5.79
Chisq= 5.8 on 1 degrees of freedom, p= 0.02
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.137e+01 5.262e-10 1.808e+04 -0.001 0.999
Likelihood ratio test=7.69 on 1 df, p=0.005547
n= 22, number of events= 6
============================
TCGA-COAD CCDC6
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 2.93 1.46 4.31
strata=LOW 11 0 2.07 2.07 4.31
Chisq= 4.3 on 1 degrees of freedom, p= 0.04
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.129e+01 5.675e-10 2.016e+04 -0.001 0.999
Likelihood ratio test=5.85 on 1 df, p=0.01555
n= 22, number of events= 5
============================
TCGA-COAD LINC00551
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 3.36 2.08 4.03
strata=LOW 11 1 3.64 1.92 4.03
Chisq= 4 on 1 degrees of freedom, p= 0.04
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -1.8886 0.1513 1.0832 -1.743 0.0812
Likelihood ratio test=4.42 on 1 df, p=0.03555
n= 22, number of events= 7
============================
TCGA-COAD MIB1
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 2.73 1.88 5.25
strata=LOW 11 0 2.27 2.27 5.25
Chisq= 5.2 on 1 degrees of freedom, p= 0.02
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.151e+01 4.555e-10 2.043e+04 -0.001 0.999
Likelihood ratio test=6.7 on 1 df, p=0.009615
n= 22, number of events= 5
============================
TCGA-COAD PIK3CA
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 3.26 2.29 6.11
strata=LOW 11 0 2.74 2.74 6.11
Chisq= 6.1 on 1 degrees of freedom, p= 0.01
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.144e+01 4.891e-10 1.818e+04 -0.001 0.999
Likelihood ratio test=7.99 on 1 df, p=0.004707
n= 22, number of events= 6
============================
TCGA-COAD GALNT14
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 5 2.07 4.17 6.76
strata=LOW 11 1 3.93 2.19 6.76
Chisq= 6.8 on 1 degrees of freedom, p= 0.009
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.45008 0.08629 1.13638 -2.156 0.0311
Likelihood ratio test=6.61 on 1 df, p=0.01013
n= 22, number of events= 6
============================
TCGA-COAD MEF2C
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 1.28 2.294 4.03
strata=LOW 11 2 3.72 0.793 4.03
Chisq= 4 on 1 degrees of freedom, p= 0.04
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.155e+01 4.392e-10 2.368e+04 -0.001 0.999
Likelihood ratio test=5.11 on 1 df, p=0.02375
n= 22, number of events= 5
============================
TCGA-COAD PARP15
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 2 4.3 1.23 5.49
strata=LOW 11 4 1.7 3.11 5.49
Chisq= 5.5 on 1 degrees of freedom, p= 0.02
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW 2.159e+01 2.385e+09 2.060e+04 0.001 0.999
Likelihood ratio test=6.93 on 1 df, p=0.008469
n= 22, number of events= 6
============================
TCGA-COAD PML
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 6 2.69 4.07 6.75
strata=LOW 11 1 4.31 2.54 6.75
Chisq= 6.8 on 1 degrees of freedom, p= 0.009
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.30627 0.09963 1.08628 -2.123 0.0337
Likelihood ratio test=6.85 on 1 df, p=0.008882
n= 22, number of events= 7
============================
TCGA-COAD AEBP2
Call:
survdiff(formula = Surv(overall_survival, deceased) ~ strata,
data = gene_df)
N Observed Expected (O-E)^2/E (O-E)^2/V
strata=HIGH 11 3 1.31 2.17 3.89
strata=LOW 11 1 2.69 1.06 3.89
Chisq= 3.9 on 1 degrees of freedom, p= 0.05
Call:
coxph(formula = Surv(overall_survival, deceased) ~ strata, data = gene_df)
coef exp(coef) se(coef) z p
strataLOW -2.151e+01 4.565e-10 2.360e+04 -0.001 0.999
Likelihood ratio test=4.99 on 1 df, p=0.02547
n= 22, number of events= 4
============================
De La Salle University, Manila, Philippines, gonzales.markedward@gmail.com↩︎
De La Salle University, Manila, Philippines, anish.shrestha@dlsu.edu.ph↩︎
---
title: "Survival Analysis"
subtitle: "Colorectal Cancer | Ferroptosis | Unique Genes per RCD Type | Gene Expression of Normal Samples"
author: 
  - Mark Edward M. Gonzales^[De La Salle University, Manila, Philippines, gonzales.markedward@gmail.com]
  - Dr. Anish M.S. Shrestha^[De La Salle University, Manila, Philippines, anish.shrestha@dlsu.edu.ph]
output: html_notebook
---

## I. Preliminaries

### Loading libraries

```{r, warning=FALSE, message=FALSE}
library("tidyverse")
library("tibble")
library("msigdbr")
library("ggplot2")
library("TCGAbiolinks")
library("RNAseqQC")
library("DESeq2")
library("ensembldb")
library("purrr")
library("magrittr")
library("vsn")
library("matrixStats")
library("dplyr")
library("grex")
library("survminer")
library("survival")
```

## II. Downloading the TCGA gene expression data 

Create a function for downloading TCGA gene expression data. 

For more detailed documentation, refer to `2. Differential Gene Expression Analysis - TCGA.Rmd`.

```{r}
query_and_filter_samples <- function(project) {
  query_tumor <- GDCquery(
    project = project,
    data.category = "Transcriptome Profiling",
    data.type = "Gene Expression Quantification",
    experimental.strategy = "RNA-Seq",
    workflow.type = "STAR - Counts",
    access = "open",
    sample.type = "Primary Tumor"
  )
  tumor <- getResults(query_tumor)

  query_normal <- GDCquery(
    project = project,
    data.category = "Transcriptome Profiling",
    data.type = "Gene Expression Quantification",
    experimental.strategy = "RNA-Seq",
    workflow.type = "STAR - Counts",
    access = "open",
    sample.type = "Solid Tissue Normal"
  )
  normal <- getResults(query_normal)

  submitter_ids <- inner_join(tumor, normal, by = "cases.submitter_id") %>%
    dplyr::select(cases.submitter_id)
  tumor <- tumor %>%
    dplyr::filter(cases.submitter_id %in% submitter_ids$cases.submitter_id)
  normal <- normal %>%
    dplyr::filter(cases.submitter_id %in% submitter_ids$cases.submitter_id)

  samples <- rbind(tumor, normal)
  unique(samples$sample_type)

  query_project <- GDCquery(
    project = project,
    data.category = "Transcriptome Profiling",
    data.type = "Gene Expression Quantification",
    experimental.strategy = "RNA-Seq",
    workflow.type = "STAR - Counts",
    access = "open",
    sample.type = c("Solid Tissue Normal", "Primary Tumor"),
    barcode = as.list(samples$sample.submitter_id)
  )

  # If this is your first time running this notebook (i.e., you have not yet downloaded the results of the query in the previous block),
  # uncomment the line below

  # GDCdownload(query_project)

  return(list(samples = samples, query_project = query_project))
}
```

Download the TCGA gene expression data for colorectal cancer (TCGA-COAD).

```{r, echo = TRUE, message = FALSE, results="hide"}
projects <- c("TCGA-COAD")

with_results_projects <- c()

samples <- list()
project_data <- list()

for (project in projects) {
  result <- tryCatch(
    {
      result <- query_and_filter_samples(project)
      samples[[project]] <- result$samples
      project_data[[project]] <- result$query_project

      with_results_projects <- c(with_results_projects, project)
    },
    error = function(e) {

    }
  )
}
```

Running the code block above should generate and populate a directory named `GDCdata`.

## III. Data preprocessing

Construct the RNA-seq count matrix for each cancer type.

```{r, echo = TRUE, message = FALSE, results="hide"}
tcga_data <- list()
tcga_matrix <- list()

projects <- with_results_projects
for (project in projects) {
  tcga_data[[project]] <- GDCprepare(project_data[[project]], summarizedExperiment = TRUE)
}
```

```{r}
for (project in projects) {
  count_matrix <- assay(tcga_data[[project]], "unstranded")

  # Remove duplicate entries
  count_matrix_df <- data.frame(count_matrix)
  count_matrix_df <- count_matrix_df[!duplicated(count_matrix_df), ]
  count_matrix <- data.matrix(count_matrix_df)
  rownames(count_matrix) <- cleanid(rownames(count_matrix))
  count_matrix <- count_matrix[!(duplicated(rownames(count_matrix)) | duplicated(rownames(count_matrix), fromLast = TRUE)), ]

  tcga_matrix[[project]] <- count_matrix
}
```
Format the `samples` table so that it can be fed as input to DESeq2.

```{r}
for (project in projects) {
  rownames(samples[[project]]) <- samples[[project]]$cases
  samples[[project]] <- samples[[project]] %>%
    dplyr::select(case = "cases.submitter_id", type = "sample_type")
  samples[[project]]$type <- str_replace(samples[[project]]$type, "Solid Tissue Normal", "normal")
  samples[[project]]$type <- str_replace(samples[[project]]$type, "Primary Tumor", "tumor")
}
```

DESeq2 requires the row names of `samples` should be identical to the column names of `count_matrix`.

```{r, echo = TRUE, results="hide"}
for (project in projects) {
  colnames(tcga_matrix[[project]]) <- gsub(x = colnames(tcga_matrix[[project]]), pattern = "\\.", replacement = "-")
  tcga_matrix[[project]] <- tcga_matrix[[project]][, rownames(samples[[project]])]

  # Sanity check
  print(all(colnames(tcga_matrix[[project]]) == rownames(samples[[project]])))
}
```

## IV. Differential gene expression analysis

For more detailed documentation on obtaining the gene set, refer to `7. Differential Gene Expression Analysis - TCGA - Pan-cancer - Unique Genes.Rmd`.

```{r}
RCDdb <- "temp/unique_genes/necroptosis_ferroptosis_pyroptosis/"
```

Write utility functions for filtering the gene sets, performing differential gene expression analysis, plotting the results, and performing variance-stabilizing transformation.

```{r}
filter_gene_set_and_perform_dgea <- function(genes) {
  tcga_rcd <- list()

  for (project in projects) {
    rownames(genes) <- genes$gene_id
    tcga_rcd[[project]] <- tcga_matrix[[project]][rownames(tcga_matrix[[project]]) %in% genes$gene_id, ]
    tcga_rcd[[project]] <- tcga_rcd[[project]][, rownames(samples[[project]])]
  }

  dds_rcd <- list()
  res_rcd <- list()

  for (project in projects) {
    print(project)
    print("=============")
    dds <- DESeqDataSetFromMatrix(
      countData = tcga_rcd[[project]],
      colData = samples[[project]],
      design = ~type
    )
    dds <- filter_genes(dds, min_count = 10)
    dds$type <- relevel(dds$type, ref = "normal")
    dds_rcd[[project]] <- DESeq(dds)
    res_rcd[[project]] <- results(dds_rcd[[project]])
  }

  deseq.bbl.data <- list()

  for (project in projects) {
    deseq.results <- res_rcd[[project]]
    deseq.bbl.data[[project]] <- data.frame(
      row.names = rownames(deseq.results),
      baseMean = deseq.results$baseMean,
      log2FoldChange = deseq.results$log2FoldChange,
      lfcSE = deseq.results$lfcSE,
      stat = deseq.results$stat,
      pvalue = deseq.results$pvalue,
      padj = deseq.results$padj,
      cancer_type = project,
      gene_symbol = genes[rownames(deseq.results), "gene"]
    )
  }

  deseq.bbl.data.combined <- bind_rows(deseq.bbl.data)
  deseq.bbl.data.combined <- dplyr::filter(deseq.bbl.data.combined, abs(log2FoldChange) >= 1.5 & padj < 0.05)

  return(deseq.bbl.data.combined)
}
```

```{r}
plot_dgea <- function(deseq.bbl.data.combined) {
  sizes <- c("<10^-15" = 4, "10^-10" = 3, "10^-5" = 2, "0.05" = 1)

  deseq.bbl.data.combined <- deseq.bbl.data.combined %>%
    mutate(fdr_category = cut(padj,
      breaks = c(-Inf, 1e-15, 1e-10, 1e-5, 0.05),
      labels = c("<10^-15", "10^-10", "10^-5", "0.05"),
      right = FALSE
    ))

  top_genes <- deseq.bbl.data.combined %>%
    group_by(cancer_type) %>%
    mutate(rank = rank(-abs(log2FoldChange))) %>%
    dplyr::filter(rank <= 10) %>%
    ungroup()

  ggplot(top_genes, aes(y = cancer_type, x = gene_symbol, size = fdr_category, fill = log2FoldChange)) +
    geom_point(alpha = 0.5, shape = 21, color = "black") +
    scale_size_manual(values = sizes) +
    scale_fill_gradient2(low = "blue", mid = "white", high = "red", limits = c(min(deseq.bbl.data.combined$log2FoldChange), max(deseq.bbl.data.combined$log2FoldChange))) +
    theme_minimal() +
    theme(
      axis.text.x = element_text(size = 9, angle = 90, hjust = 1)
    ) +
    theme(legend.position = "bottom") +
    theme(legend.position = "bottom") +
    labs(size = "Adjusted p-value", fill = "log2 FC", y = "Cancer type", x = "Gene")
}
```

```{r}
perform_vsd <- function(genes) {
  tcga_rcd <- list()

  for (project in projects) {
    rownames(genes) <- genes$gene_id
    tcga_rcd[[project]] <- tcga_matrix[[project]][rownames(tcga_matrix[[project]]) %in% genes$gene_id, ]
    tcga_rcd[[project]] <- tcga_rcd[[project]][, rownames(samples[[project]])]
  }

  vsd_rcd <- list()

  for (project in projects) {
    print(project)
    print("=============")
    dds <- DESeqDataSetFromMatrix(
      countData = tcga_rcd[[project]],
      colData = samples[[project]],
      design = ~type
    )
    dds <- filter_genes(dds, min_count = 10)

    # Perform variance stabilization
    dds <- estimateSizeFactors(dds)
    nsub <- sum(rowMeans(counts(dds, normalized = TRUE)) > 10)
    vsd <- vst(dds, nsub = nsub)
    vsd_rcd[[project]] <- assay(vsd)
  }

  return(vsd_rcd)
}
```


#### Ferroptosis

Fetch the gene set of interest.

```{r}
genes <- read.csv(paste0(RCDdb, "Ferroptosis.csv"))
print(genes)
genes$gene_id <- cleanid(genes$gene_id)
genes <- distinct(genes, gene_id, .keep_all = TRUE)
genes <- subset(genes, gene_id != "")
genes
```

Filter the genes to include only those in the gene set of interest, and then perform differential gene expression analysis.

```{r}
deseq.bbl.data.combined <- filter_gene_set_and_perform_dgea(genes)
deseq.bbl.data.combined
```

Plot the results.

```{r}
plot_dgea(deseq.bbl.data.combined)
```
Perform variance-stabilizing transformation for further downstream analysis (i.e., for survival analysis).

```{r, warning=FALSE}
vsd <- perform_vsd(genes)
```

## V. Downloading the clinical data

Download clinical data from TCGA, and perform some preprocessing:
- The `deceased` column should be `FALSE` if the patient is alive and `TRUE` otherwise
- The `overall_survival` column should reflect the follow-up time if the patient is alive and the days to death otherwise

```{r}
download_clinical_data <- function(project) {
  clinical_data <- GDCquery_clinic(project)
  clinical_data$deceased <- ifelse(clinical_data$vital_status == "Alive", FALSE, TRUE)
  clinical_data$overall_survival <- ifelse(clinical_data$vital_status == "Alive",
    clinical_data$days_to_last_follow_up,
    clinical_data$days_to_death
  )

  return(clinical_data)
}
```

```{r}
tcga_clinical <- list()
for (project in projects) {
  tcga_clinical[[project]] <- download_clinical_data(project)
}
```

## VI. Performing survival analysis

Write utility functions for performing survival analysis.


```{r}
construct_gene_df <- function(gene_of_interest, project) {
  gene_df <- vsd[[project]] %>%
    as.data.frame() %>%
    rownames_to_column(var = "gene_id") %>%
    gather(key = "case_id", value = "counts", -gene_id) %>%
    left_join(., genes, by = "gene_id") %>%
    dplyr::filter(gene == gene_of_interest) %>%
    dplyr::filter(case_id %in% rownames(samples[[project]] %>% dplyr::filter(type == "normal")))

  q1 <- quantile(gene_df$counts, probs = 0.25)
  q3 <- quantile(gene_df$counts, probs = 0.75)
  gene_df$strata <- ifelse(gene_df$counts >= q3, "HIGH", ifelse(gene_df$counts <= q1, "LOW", "MIDDLE"))
  gene_df <- gene_df %>% dplyr::filter(strata %in% c("LOW", "HIGH"))
  gene_df$case_id <- paste0(sapply(strsplit(as.character(gene_df$case_id), "-"), `[`, 1), '-',
                          sapply(strsplit(as.character(gene_df$case_id), "-"), `[`, 2), '-', 
                          sapply(strsplit(as.character(gene_df$case_id), "-"), `[`, 3))
  gene_df <- merge(gene_df, tcga_clinical[[project]], by.x = "case_id", by.y = "submitter_id")
  
  return(gene_df)
}
```

```{r}
compute_surival_fit <- function(gene_df) {
  return (survfit(Surv(overall_survival, deceased) ~ strata, data = gene_df))
}
```

```{r}
compute_cox <- function(gene_df) {
  return (coxph(Surv(overall_survival, deceased) ~ strata, data=gene_df))
}
```

```{r}
plot_survival <- function(fit) {
  return(ggsurvplot(fit,
    data = gene_df,
    pval = T,
    risk.table = T,
    risk.table.height = 0.3
  ))
}
```

```{r}
compute_survival_diff <- function(gene_df) {
  return(survdiff(Surv(overall_survival, deceased) ~ strata, data = gene_df))
}
```

Perform survival analysis by testing for the difference in the Kaplan-Meier curves using the G-rho family of Harrington and Fleming tests: https://rdrr.io/cran/survival/man/survdiff.html

Our genes of interest are the differentially expressed genes.

```{r}
significant_projects <- c()
significant_genes <- c()

ctr <- 1
for (project in projects) {
  for (gene in c(genes$gene)) {
    cat(project, gene, "\n\n")
    error <- tryCatch (
      {
        gene_df <- construct_gene_df(gene, project)
      },
      error = function(e) {
        cat("\n\n============================\n\n")
        e
      }
    )
    
    if(inherits(error, "error")) next

    if (nrow(gene_df) > 0) {
      fit <- compute_surival_fit(gene_df)
      tryCatch (
        {
          survival <- compute_survival_diff(gene_df)
          cox <- compute_cox(gene_df)
          print(ctr)
          ctr <- ctr + 1
          print(survival)
          cat("\n")
          print(cox)
          print(plot_survival(fit))
          if (pchisq(survival$chisq, length(survival$n)-1, lower.tail = FALSE) < 0.05) {
            significant_projects <- c(significant_projects, project)
            significant_genes <- c(significant_genes, gene)
          }
        },
        error = function(e) {
        }
      )
      
    }
    
    cat("\n\n============================\n\n")
  }
}
```

Display the results only for genes where a significant difference in survival has been reported.

```{r}
significant_genes
```

```{r}
num_significant_genes <- length(significant_genes)

if (num_significant_genes > 0) {
  for (i in 1 : num_significant_genes) {
    project <- significant_projects[[i]]
    gene <- significant_genes[[i]]
    
    cat(project, gene, "\n\n")
    gene_df <- construct_gene_df(gene, project)
    
    fit <- compute_surival_fit(gene_df)
    survival <- compute_survival_diff(gene_df)
    cox <- compute_cox(gene_df)
    print(survival)
    cat("\n")
    print(cox)
    print(plot_survival(fit))
    
    cat("\n\n============================\n\n")
  } 
}
```